Effect of Somatic Variants Post Allogeneic Hematopoietic Cell Transplantation in Acute Myeloid Leukemia and Myelodysplastic Syndrome [0.03%]
Madiha Iqbal,Himil Mahadevia,Zhuo Li et al.
Madiha Iqbal et al.
Measurable residual disease (MRD) has established prognostic significance in patients with myeloid disorders; however, there is limited data regarding its prognostic and predictive value and the optimal technique for measurement in the sett...
Amal Aljuhani,Mohamed Aseafan,Ali Sheikh et al.
Amal Aljuhani et al.
Background and objective: Gastric and gastroesophageal junction (G/GEJ) cancers, with their poor prognosis, pose management challenges. Treatments like perioperative chemotherapy, neoadjuvant chemoradiotherapy, and adjuva...
Epidemiology and Outcomes of Hospitalized Patients with Hematological Malignancy and Acute Respiratory Failure [0.03%]
血液系统恶性肿瘤伴急性呼吸衰竭住院患者的流行病学及结局研究
Anoosha Ponnapalli,Aditya Sharma,Mariam Fatima et al.
Anoosha Ponnapalli et al.
Introduction: Patients with hematologic malignancies are at increased risk for acute respiratory failure (ARF), which is a leading cause of intensive care units admission and mortality in this population. This study aimed...
Patients with Fanconi Anemia Have an Increased Incidence of Diabetes Mellitus After Allogeneic Stem Cell Transplantation [0.03%]
Fanconi贫血症患者在异基因干细胞移植后发生糖尿病的概率增加
Mouhab Ayas,Khawar Siddiqui,Abdullah Al-Jefri et al.
Mouhab Ayas et al.
Epidemiology and Outcomes of Hepatic Veno-Occlusive Disease after Allogeneic Hematopoietic Stem Cell Transplantation: A Descriptive Analysis of the U.S. National Inpatient Sample [0.03%]
美国全国住院样本肝静脉闭塞性疾病allo-HSCT后流行病学和结局的描述性分析
Aditya Sharma,Sarvani Surapaneni,Aditi Sharma et al.
Aditya Sharma et al.
Introduction: Hepatic veno-occlusive disease (HVOD), or sinusoidal obstruction syndrome (SOS), is a potentially liefe-threatening complication following allogeneic stem cell transplantation (allo-SCT). Historically, HVOD ...
Antibody-Drug Conjugates (ADCs) for Breast Cancer Therapeutic Landscape: Concept and Mechanisms of Action [0.03%]
抗体药物偶联物(ADC)在乳腺癌治疗领域的概念及作用机制
Roberto Paz-Manrique,Joseph A Pinto,Henry L Gomez Moreno
Roberto Paz-Manrique
The concept of a "magic bullet" in oncology-first envisioned by Paul Ehrlich-has evolved into one of the most dynamic areas in precision cancer therapeutics: antibody-drug conjugates (ADCs). These biopharmaceuticals combine the selectivity ...
Myeloablative and Reduced Intensity Allogeneic Transplant in Patients with Myeloproliferative Neoplasms [0.03%]
用于骨髓增生性肿瘤患者的清髓和减低强度的异基因移植
Andrew D Trunk,Yanwen Chen,Aaron T Gerds et al.
Andrew D Trunk et al.
Background: Allogeneic hematopoietic cell transplant (allo-HCT) is the only potentially curative treatment for myelofibrosis (MF) and chronic myelomonocytic leukemia (CMML). Older age, comorbidities, and often advanced di...
Patterns of Graft-Versus-Host Disease (GvHD) Prevention Practices in the Eastern Mediterranean (EM) Region: A Worldwide Network for Blood & Marrow Transplantation (WBMT) Global Study [0.03%]
东地中海地区骨髓移植后移植物抗宿主病预防实践模式：一项全球血癌与骨髓移植协会研究项目
Ibrahim N Muhsen,Dietger Niederwieser,Laurent Garderet et al.
Ibrahim N Muhsen et al.
Background: Preventing graft vs. host disease (GvHD) after allogeneic hematopoietic stem cell transplant (allo-HSCT) is essential to improving the outcomes and quality of life of allo-HSCT recipients. Little is known abou...
Allogeneic hematopoietic cell transplantation as the standard of care for blastic plasmacytoid dendritic cell neoplasm in first complete remission [0.03%]
allo-HSCT应作为BPDCN初治完全缓解患者的标准化疗后巩固治疗手段
Mohamed A Kharfan-Dabaja
Mohamed A Kharfan-Dabaja
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic disorder derived from precursors of plasmacytoid dendritic cells, with a generally aggressive clinical course. Tagraxofusp, a first-in-class CD123-directed antibody ...
Impact of TMPRSS6 gene polymorphism on iron overload among children with sickle cell disease [0.03%]
TMPRSS6基因多态性对镰状细胞病儿童铁过载的影响
Eman A El-Bostany,Eman A Elghoroury,Eman H Thabet et al.
Eman A El-Bostany et al.
Objective/background: Iron overload is a significant problem in transfusion-dependent children with sickle cell disease (SCD). The molecular mechanisms underlying the progression to iron overload in SCD are poorly underst...