A case-control study investigating the impact of gradient pressure therapy on chemotherapy-induced peripheral neuropathy symptoms and daily activities in paclitaxel-treated patients [0.03%]
一项关于梯度压力疗法对紫杉醇治疗患者化疗诱发的外周神经毒性症状和日常生活活动影响的病例对照研究
Dongxue Guo,Fangfei Zhao,JiWei Hu et al.
Dongxue Guo et al.
Purpose: Paclitaxel chemotherapy is known to induce peripheral neuropathy, significantly impacting patients' daily activities. Effective interventions to alleviate these symptoms are crucial for improving patient quality ...
Randomized Controlled Trial
Journal of the Egyptian National Cancer Institute. 2025 Nov 24;37(1):75. DOI:10.1186/s43046-025-00331-w 2025
New insights into the effects of microbiome and its derived metabolites on targeted immunotherapy [0.03%]
微生物组及其衍生代谢物对免疫治疗的影响机制研究新见解
Maged Tharwat Elghannam,Moataz Hassan Hassanien,Yosry Abdel Rahman Ameen et al.
Maged Tharwat Elghannam et al.
The significance of gut bacteria and their byproducts is gaining greater recognition, especially in the realm of immunotherapy. An imbalance in gut bacteria or their byproducts is intricately linked to the onset, progression, and treatment ...
Charlène G S Soro,Sara Benchikh,Adil El Hamouchi et al.
Charlène G S Soro et al.
Background: Whole-genome sequencing has enabled the development of a wide range of analytical tools to search for abnormalities associated with tumors. As classic myeloproliferative neoplasms (MPNs) are associated with ge...
Adhi Kesava Naidu Neelam
Adhi Kesava Naidu Neelam
Background: The convergence of biology and nanomaterials has propelled technological progress in biomedical sciences, offering transformative applications in diagnostics and therapy. Among these advancements, quantum dots...
The role of stem cells in precision medicine: next-generation cancer treatment [0.03%]
精准医疗中的干细胞角色：下一代癌症治疗方案
Hafsa Iqbal,Bibi Khadija
Hafsa Iqbal
Background: Precision medicine has transformed oncology by tailoring treatments to the molecular and genetic characteristics of individual tumors. Stem cell-based strategies hold unique potential to complement these appro...
Zahraa Isam Jameel,Halla Abdul-Hadi Chabuk
Zahraa Isam Jameel
Long non-coding ribonucleic acids (LncRNAs) are larger than 200 nucleotides and resemble messenger ribonucleic acids (mRNAs), but they do not code for proteins. In both cell development and physiological cell function, LncRNAs have crucial ...
Dual-modality treatment using gamma radiation and ZnO nanoparticles: effects on normal and malignant lung cells [0.03%]
使用γ射线和ZnO纳米粒子的双模态治疗及其对正常和恶性肺癌细胞的影响
Naglaa M Ismail,Soheir Korraa,Amira Abdel Rehim Qotb
Naglaa M Ismail
This study primarily aims to investigate the effects of gamma (γ) radiation, both independently and in combination with zinc oxide nanoparticles (ZnO NPs), on normal and lung cancer cell lines. Lung cancer continues to be a major cause of ...
Comprehensive evaluation of high dose methotrexate therapy: a retrospective observational trial [0.03%]
高剂量甲氨蝶呤治疗的全面评估：一项回顾性观察研究
Hadeer Ehab Barakat,Kholood Ashraf El Bahy,Sandy Victor Labib et al.
Hadeer Ehab Barakat et al.
Background: Methotrexate (MTX) is a commonly prescribed drug with both chemotherapeutic and immunosuppressive applications. However, when administered in high doses (HDMTX ≥ 500 mg/m2), it can lead to serious side effect...
Predictive radiomics based ensemble machine learning approach in CT lung nodule diagnosis [0.03%]
基于CT肺结节诊断的预测影像组学集成机器学习方法
Arooj Nissar,A H Mir
Arooj Nissar
Background: Computed tomography imaging, a non-invasive tool, is used around the globe by medical professionals to identify and diagnose lung cancer; a lethal disease with high rates of occurrence and mortality globally. ...
Pancreatic cancer in the era of precision medicine: challenges, advances, and the future of therapeutic strategies [0.03%]
精准医学时代的胰腺癌：挑战、进展和未来治疗策略
Heslley Machado Silva,Reginaldo Cruz Alves Rosa
Heslley Machado Silva
Background: Pancreatic cancer stands among the most aggressive and fatal malignancies, with a steadily increasing incidence worldwide. Its clinical significance lies not only in its high mortality rate but also in the cha...