Circulating microRNAs: a new era in early detection of oral squamous cell carcinoma (OSCC) - a systematic review and meta-analysis [0.03%]
循环miRNA在口腔鳞状细胞癌(OSCC)早期检测中的应用-系统评价和Meta分析
Roshan Mustafa Pathan,Umadevi Subramanian,Jugraj Singh et al.
Roshan Mustafa Pathan et al.
Background: The chances of oral squamous cell carcinoma (OSCC) being diagnosed at an early stage are very low, and this leads to a poor prognosis. The presence of circulating miRNAs (miRNAs) in blood or saliva is now a po...
Pooled safety profiles of bispecific antibodies targeting PD-1/CTLA-4 or PD-1/VEGF in non-small cell lung cancer: a systematic review and single-arm meta-analysis [0.03%]
PD-1/CTLA-4或PD-1/VEGF双特异性抗体在非小细胞肺癌中的汇总安全性特征：系统性回顾和单臂Meta分析
Jiayun Ma,Weixing Zhao
Jiayun Ma
Objective: This study aimed to systematically synthesize and separately quantify the pooled safety profiles of bispecific antibodies (BsAbs) targeting PD-1/CTLA-4 or PD-1/VEGF in patients with non-small cell lung cancer (...
MSA U-Net: a multi-scale attention-enhanced network for automatic segmentation of uterine lymph nodes in MRI images [0.03%]
一种用于MRI图像中子宫淋巴结自动分割的多尺度注意力增强网络方法(MSA U-Net)
Jingde Hong,Chunxia Chen,Juping Qiu et al.
Jingde Hong et al.
Objective: Lymph nodes (LNs) in medical images often have fuzzy boundaries, vary in size and shape, and have intensities similar to those of neighboring tissues, making accurate segmentation challenging. To address this i...
Real-world efficacy and safety of CDK4/6 inhibitors plus endocrine therapy in HR+/HER2 - metastatic breast cancer: a single-institution experience [0.03%]
CDK4/6抑制剂联合内分泌治疗HR+/HER2-转移性乳腺癌的疗效和安全性：单中心经验
Nawal E Hussein,Ahmed M Gad,Abeer AbdAllah et al.
Nawal E Hussein et al.
Background: Hormone receptor-positive, HER2-negative (HR+/HER2-) metastatic breast cancer is the most common type of advanced breast cancer. The addition of cyclin-dependent kinase 4/6 (CDK4/6) inhibitors to endocrine the...
The promising role of engineered T lymphocytes in immunotherapy for high-grade serous ovarian carcinoma: a review of mechanisms, clinical landscape, and future strategies [0.03%]
卵巢癌免疫治疗中工程T淋巴细胞的作用及机制、临床格局和未来策略展望综述
Dwi Faradina,Muhammad Rusda,Muhammad Fidel Ganis Siregar et al.
Dwi Faradina et al.
High-grade serous ovarian carcinoma (HGSC) demonstrates poor prognosis with approximately 80% recurrence rates and significant chemotherapy resistance. Conventional checkpoint inhibitors show limited efficacy (10-15%), necessitating alterna...
Clinical efficacy and safety outcomes of anlotinib therapy in sarcoma: a systematic review and meta-analysis [0.03%]
アンロチニブ治療の肉腫に対する臨床効果と安全性：系統レビューおよびメタアナリシス
Hasan Matar,Ahmad Melhem,Abdallah Shawwa et al.
Hasan Matar et al.
Purpose: Sarcomas are rare, aggressive and unpredictable tumors that arise from mesenchymal tissues. Despite treatment, outcomes for advanced or metastatic cases remain poor. Anlotinib is a new oral tyrosine kinase inhibi...
Efficacy and safety of antibody-drug conjugates in HER2-positive and HER2-low advanced gastric cancer: a systematic review and update [0.03%]
抗体偶联药物治疗HER2阳性和HER2低表达晚期胃癌的疗效和安全性：系统评价和更新
Lili Lei,Kun Hu,Shuangwei Xie et al.
Lili Lei et al.
Purpose: Gastric cancer is a highly prevalent malignancy of the digestive tract in China. Conventional chemotherapeutic drugs and human epidermal growth factor receptor 2 (HER2)‑targeted agents such as trastuzumab remain...
Disclosure of gynecological cancer diagnosis: a mixed-methods study from an Islamic cultural context [0.03%]
妇科癌症诊断披露：伊斯兰文化背景下的混合方法研究
Israa Malli,Hatim Al-Jifree,Farah Bakhamees et al.
Israa Malli et al.
Background: Delivering devastating news of cancer is a universal challenge, but cultural and religious contexts impact disclosure. In Saudi Arabia, family engagement frequently influences communication, yet little is know...
Liquid crystal thermography for breast cancer detection: principles, current evidence, limitations, and future directions [0.03%]
乳腺癌检测的液晶热图技术：原理、现有证据、局限性及未来发展方向
Ainnur Bazilah Mohd Sha&#x;ari,Heba Mohammed Arafat,Tengku Ahmad Damitri Al Astani Tengku Din et al.
Ainnur Bazilah Mohd Sha&#x;ari et al.
Breast cancer remains a leading cause of cancer-related mortality in women worldwide, making early and accurate detection a global clinical priority. Conventional screening modalities, including mammography, ultrasonography, and Magnetic Re...
Immune organoids for Africa: a roadmap for bridging the innovation gap in infectious diseases and cancer research [0.03%]
面向非洲的免疫器官体：弥合传染病和癌症研究创新差距的战略指南
Ahmad Onikoko Abdulgafar,Adeyemi Sallam Febilola,Catherine Rono et al.
Ahmad Onikoko Abdulgafar et al.
Background: Sub-Saharan Africa bears approximately 25% of the global disability-adjusted life-year (DALY) burden yet contributes fewer than 3% of global health research outputs. HIV/AIDS, tuberculosis (TB), and malaria co...