A narrative review of therapy-induced senescence in cancer: mechanisms, immune interplay, and therapeutic opportunities [0.03%]
癌症治疗诱导衰老的叙事性综述：机制、免疫相互作用和治疗机会
Henry Sutanto,Alfan Ahkami,Deasy Fetarayani et al.
Henry Sutanto et al.
Prognostic value of tumor budding in muscle-invasive urothelial carcinoma of the bladder [0.03%]
肌层浸润性膀胱尿路上皮癌中肿瘤芽的预后价值
Ahlem Bdioui,Asma Mahmoudi,Zaineb Lajmi et al.
Ahlem Bdioui et al.
A case-control study investigating the impact of gradient pressure therapy on chemotherapy-induced peripheral neuropathy symptoms and daily activities in paclitaxel-treated patients [0.03%]
一项关于梯度压力疗法对紫杉醇治疗患者化疗诱发的外周神经毒性症状和日常生活活动影响的病例对照研究
Dongxue Guo,Fangfei Zhao,JiWei Hu et al.
Dongxue Guo et al.
Purpose: Paclitaxel chemotherapy is known to induce peripheral neuropathy, significantly impacting patients' daily activities. Effective interventions to alleviate these symptoms are crucial for improving patient quality ...
Randomized Controlled Trial
Journal of the Egyptian National Cancer Institute. 2025 Nov 24;37(1):75. DOI:10.1186/s43046-025-00331-w 2025
New insights into the effects of microbiome and its derived metabolites on targeted immunotherapy [0.03%]
微生物组及其衍生代谢物对免疫治疗的影响机制研究新见解
Maged Tharwat Elghannam,Moataz Hassan Hassanien,Yosry Abdel Rahman Ameen et al.
Maged Tharwat Elghannam et al.
The significance of gut bacteria and their byproducts is gaining greater recognition, especially in the realm of immunotherapy. An imbalance in gut bacteria or their byproducts is intricately linked to the onset, progression, and treatment ...
Charlène G S Soro,Sara Benchikh,Adil El Hamouchi et al.
Charlène G S Soro et al.
Background: Whole-genome sequencing has enabled the development of a wide range of analytical tools to search for abnormalities associated with tumors. As classic myeloproliferative neoplasms (MPNs) are associated with ge...
Adhi Kesava Naidu Neelam
Adhi Kesava Naidu Neelam
Background: The convergence of biology and nanomaterials has propelled technological progress in biomedical sciences, offering transformative applications in diagnostics and therapy. Among these advancements, quantum dots...
The role of stem cells in precision medicine: next-generation cancer treatment [0.03%]
精准医疗中的干细胞角色：下一代癌症治疗方案
Hafsa Iqbal,Bibi Khadija
Hafsa Iqbal
Background: Precision medicine has transformed oncology by tailoring treatments to the molecular and genetic characteristics of individual tumors. Stem cell-based strategies hold unique potential to complement these appro...
Zahraa Isam Jameel,Halla Abdul-Hadi Chabuk
Zahraa Isam Jameel
Long non-coding ribonucleic acids (LncRNAs) are larger than 200 nucleotides and resemble messenger ribonucleic acids (mRNAs), but they do not code for proteins. In both cell development and physiological cell function, LncRNAs have crucial ...
Dual-modality treatment using gamma radiation and ZnO nanoparticles: effects on normal and malignant lung cells [0.03%]
使用γ射线和ZnO纳米粒子的双模态治疗及其对正常和恶性肺癌细胞的影响
Naglaa M Ismail,Soheir Korraa,Amira Abdel Rehim Qotb
Naglaa M Ismail
This study primarily aims to investigate the effects of gamma (γ) radiation, both independently and in combination with zinc oxide nanoparticles (ZnO NPs), on normal and lung cancer cell lines. Lung cancer continues to be a major cause of ...
Comprehensive evaluation of high dose methotrexate therapy: a retrospective observational trial [0.03%]
高剂量甲氨蝶呤治疗的全面评估：一项回顾性观察研究
Hadeer Ehab Barakat,Kholood Ashraf El Bahy,Sandy Victor Labib et al.
Hadeer Ehab Barakat et al.
Background: Methotrexate (MTX) is a commonly prescribed drug with both chemotherapeutic and immunosuppressive applications. However, when administered in high doses (HDMTX ≥ 500 mg/m2), it can lead to serious side effect...