Detection of activating mutations in liquid biopsy of Egyptian breast cancer patients using targeted next-generation sequencing: a pilot study [0.03%]
针对埃及乳腺癌患者液态活检样本中激活突变的检测:一项基于靶向高通量测序的小规模研究
Neemat Kassem,Hebatallah Kassem,Loay Kassem et al.
Neemat Kassem et al.
Background: Breast cancer (BC) is the 2nd most prevalent malignancy worldwide and is the most prevalent cancer among Egyptian women. The number of newly described cancer-associated genes has grown exponentially since the ...
Retrospective study of Dana Farber Consortium Protocol in newly diagnosed Egyptian adolescents and young adults with acute lymphoblastic leukemia: Tanta experience [0.03%]
戴娜法伯联盟计划治疗新诊断的埃及青少年及年轻成人急性淋巴细胞白血病患者:塔anta经验回顾性研究
Hossam Eldin A Elashtokhy,Heba E Elgohary,Basant B Eldeep et al.
Hossam Eldin A Elashtokhy et al.
Background: Intensive acute lymphoblastic leukemia (ALL) regimens in children improve the 5-year event-free survival (EFS) to reach ~ 90%. Adolescents and young adults (AYA) have EFS (30% to 45%). Young AYA ALL patients t...
Mariah Farrugia,Catriona Cutajar,Jean Calleja Agius et al.
Mariah Farrugia et al.
Background: In 2018, leukaemia accounted for 2.6% of all new cancers, it being the 13th most common cause of cancer and the 10th most common cause of cancer death. Glucocorticoids are commonly used in lymphoid leukaemia t...
Kamal Bandhu Klanidhi,S Ashwin Monian,Avinash Chakrawarty
Kamal Bandhu Klanidhi
Background: Acral vascular syndrome clinically presents as digital ischemia with Raynaud's phenomenon and erythromelalgia but can be rarely seen in the malignant condition. Patients may present pain, permanent digital bla...
The implications of a pathological complete response of the primary tumour after neoadjuvant chemotherapy for breast cancer on axillary surgery [0.03%]
新辅助化疗后乳腺癌原发灶病理完全缓解对腋窝手术的含义
Mina M G Youssef,Ahmed A Metwally,Tamer M Manie
Mina M G Youssef
Background: Management of the node-positive axilla after neoadjuvant chemotherapy is controversial. The aim of this study is to predict the group of patients who may require a less invasive approach for axillary managemen...
Drug delivery nanocarriers and recent advances ventured to improve therapeutic efficacy against osteosarcoma: an overview [0.03%]
药物输送纳米载体及近期致力于提高治疗效果的骨肉瘤研究进展综述
Sujit Arun Desai,Arehalli Manjappa,Preeti Khulbe
Sujit Arun Desai
Background: Osteosarcoma (OS) is one of the key cancers affecting the bone tissues, primarily occurred in children and adolescence. Recently, chemotherapy followed by surgery and then post-operative adjuvant chemotherapy ...
Medulloblastoma: clinicopathological parameters, risk stratification, and survival analysis of immunohistochemically validated molecular subgroups [0.03%]
髓母细胞瘤的临床病理参数、风险分层及免疫组化验证的分子亚群生存分析
Asmaa Mustafa Eid,Nehal Abd El-Ghaffar Heabah
Asmaa Mustafa Eid
Background: Medulloblastoma (MB) is a heterogeneous disease, displaying distinct genetic profiles with specific molecular subgroups. This study aimed to validate MB molecular subgrouping using surrogate immunohistochemist...
Vaginal metastasis in solid tumours: our four cases and review of the literature [0.03%]
实体肿瘤的阴道转移:四例报道及文献复习
Mustafa Korkmaz,Melek Karakurt Eryılmaz,Ülkü Kerimoğlu et al.
Mustafa Korkmaz et al.
Background: Vaginal metastasis should be kept in mind when evaluating the staging tests of all cancers, especially endometrial cancer. Case presentation: ...
Renal angiomyoadenomatous tumor (RAT): a rare distinct entity with diagnostic challenges-a case report [0.03%]
肾血管肌脂肪瘤(RAT):一种罕见且具有诊断挑战的特殊实体——病例报告
Ankur Majumder,Ravi Hari Phulware,Arvind Ahuja et al.
Ankur Majumder et al.
Background: Renal angiomyoadenomatous tumor (RAT) is a recently described rare renal neoplasm with variations in the presentation, gross, and microscopic findings, and having a benign course and good prognosis. It is char...
Feasibility of Monte-Carlo algorithm in comparison with collapse-cone dose calculation algorithm of a commercial treatment planning system in the presence of high-density metallic implant: a dosimetric study [0.03%]
含高密度金属植入物情况下蒙特卡洛算法与商业治疗计划系统坍缩锥束剂量计算算法对比的可行性研究:一项剂量学研究
Manindra Bhushan,Deepak Tripathi,Girigesh Yadav et al.
Manindra Bhushan et al.
Background: The number of people with implanted hip prosthesis has grown worldwide. For radiotherapy planning of patients with hip implants, few main challenges are encountered. The aim of the present study was to evaluat...