Chloroform extract and acetyl-11-keto-beta-boswellic acid from Boswellia dalzielii stem bark induce apoptosis and cell cycle blockage in AW8507 cells [0.03%]
乳香树干皮氯仿提取物和乙酰-11-κ-β-波斯宁酸通过诱导凋亡及细胞周期阻滞抑制AW8507细胞生长
Akinbobola Peace Otitoju,Ishaya Yohanna Longdet,Taiwo Emmanuel Alemika et al.
Akinbobola Peace Otitoju et al.
Background: Globally, head and neck cancer is the sixth most common cancer. Despite the advancement in treatment, drug resistance remains a major cause for setback. In an earlier work, the authors reported that Boswellia ...
The integrative bioinformatic analysis deciphers the predicted molecular target gene and pathway from curcumin derivative CCA-1.1 against triple-negative breast cancer (TNBC) [0.03%]
整合生物信息学分析解码了 curry 衍生物 CCA-1.1 针对三阴性乳腺癌的作用分子靶基因和通路
Dhania Novitasari,Riris Istighfari Jenie,Jun-Ya Kato et al.
Dhania Novitasari et al.
Background: The poor outcomes from triple-negative breast cancer (TNBC) therapy are mainly because of TNBC cells' heterogeneity, and chemotherapy is the current approach in TNBC treatment. A previous study reported that C...
Intussusception in a child with Acute Lymphoblastic Leukemia: a remarkable presentation with literature review - a case report [0.03%]
急性淋巴细胞白血病患儿肠套叠一例并文献复习
Ankur Majumder,Sunayana Misra,Vijay Kumar et al.
Ankur Majumder et al.
Background: Gastrointestinal complications are not uncommon in patients of Acute Leukemia. Intussusception as a complication in leukemia, although described, is exceedingly rare. Also, it is usually seen after chemotherap...
Green tea catechins in combination with irinotecan attenuates tumorigenesis and treatment-associated toxicity in an inflammation-associated colon cancer mice model [0.03%]
绿茶儿茶素联合伊立替康在炎症相关结肠癌小鼠模型中抑制肿瘤发生及治疗相关毒性的作用研究
Gaurab Borah,Manuj Kumar Bharali
Gaurab Borah
Background: Administration of green tea (GT) catechins has been reported to ensue antitumor activity in combination with chemotherapeutic drugs against different cancer types. Irinotecan (IRN) is a highly effective chemot...
Programmed death ligand-1 and CD8 tumor-infiltrating lymphocytes (TILs) as prognostic predictors in ovarian high-grade serous carcinoma (HGSC) [0.03%]
程序性死亡配体-1和CD8肿瘤浸润淋巴细胞(TILs)在卵巢高级别浆液性癌(HGSC)中的预后预测作用
Mayada Saad Farrag,Khaled Abdelwahab,Nesrine Saad Farrag et al.
Mayada Saad Farrag et al.
Background: P D-L1 is expressed in tumor cells and plays a crucial role in tumor immune escape. Tumor-infiltrating lymphocytes (TILs) as CD8 T cells contribute to reduced tumor growth. Few studies investigated the prognos...
Ayodipupo S Oguntade,Faez Al-Amodi,Abdullah Alrumayh et al.
Ayodipupo S Oguntade et al.
Background: Angiogenesis is the formation of new vascular networks from preexisting ones through the migration and proliferation of differentiated endothelial cells. Available evidence suggests that while antiangiogenic t...
Aberrant expression of multiple T cell markers on diffuse large B cell lymphoma: a case report [0.03%]
弥漫性大B细胞淋巴瘤中T细胞标志物的异常表达：1例报告
Anurag Mehta,Prerna Chadha,Poojan Agarwal et al.
Anurag Mehta et al.
Background: Aberrant T cell antigen expression has been well documented in diffuse large B cell lymphomas. However, co-expression of multiple T cell antigens including CD3, which has been considered a specific marker for ...
Umesh Jayarajah,Anuruddha M Abeygunasekera
Umesh Jayarajah
Background: The burden of cancer in Sri Lanka is on the rise. The overall incidence of cancer in Sri Lanka has doubled over the past 25 years with a parallel rise in cancer-related mortality. Cancer has become the second ...
Post hoc analysis of a randomized controlled trial comparing concurrent chemoradiation with cisplatin versus nimotuzumab-cisplatin, focusing on acute oral mucositis [0.03%]
顺铂与尼莫单抗-顺铂联合放化疗治疗局部区域复发性鼻咽癌的随机对照试验的事后分析：重点为急性口腔黏膜炎
Vanita Noronha,Vijay M Patil,Gunjesh Kumar Singh et al.
Vanita Noronha et al.
Background: Acute oral mucositis has been infrequently studied in the patients with head and neck squamous cell carcinoma (HNSCC) receiving once-weekly cisplatin-based chemoradiotherapy (CRT). Hence, this analysis was con...
Randomized Controlled Trial
Journal of the Egyptian National Cancer Institute. 2021 May 22;33(1):12. DOI:10.1186/s43046-021-00069-1 2021
The role of PI3K signaling pathway and its associated genes in papillary thyroid cancer [0.03%]
PI3K信号通路及其相关基因在乳头状甲状腺癌中的作用分析
Elham Amjad,Solmaz Asnaashari,Babak Sokouti
Elham Amjad
Background: One of the well-differentiated types of thyroid cancer is papillary thyroid cancer (PTC), often developed by genetic mutations and radiation. ...