Tissue engineering driven regeneration in oral squamous cell carcinoma: from biomaterials to precision gene editing [0.03%]
组织工程驱动的口腔鳞状细胞癌再生：从生物材料到精确基因编辑
B Deva Darshinii,N Subhapradha,S Raghavi et al.
B Deva Darshinii et al.
Oral cancer is a significant global health challenge, ranking as the sixth most prevalent cancer worldwide, with approximately 377,000 new cases diagnosed annually. The high morbidity and mortality rates are largely attributed to tobacco an...
Metabolic and nutritional impact of gastrectomy and perioperative treatment in gastric cancer: a prospective cohort study [0.03%]
胃癌手术及围手术期处理的代谢和营养影响：前瞻性队列研究
Tomasz Muszyński,Tomasz Jędrychowski,Adrianna Witalewska et al.
Tomasz Muszyński et al.
Background: Gastrectomy due to gastric cancer leads to metabolic alterations in body composition, significantly affecting nutritional status. This prospective study aimed to investigate the metabolic effects of gastrectom...
Metformin enhances methylene blue-mediated photodynamic therapy in oral squamous cell carcinoma [0.03%]
二甲双胍增强亚甲蓝介导的光动力疗法治疗口腔鳞状细胞癌
Mohamed A Osman,Marwa Sharaky,Hesham Abdel-Fattah et al.
Mohamed A Osman et al.
Background: Head and neck squamous cell carcinoma (HNSCC) is the most common malignancy of the head and neck region with relatively low survival rate and response and high resistance to treatment. Tongue and floor of the ...
Programmed cell death protein 1 (PD-1) / programmed cell death ligand 1 (PD-L1) in multiple myeloma [0.03%]
程序性细胞死亡蛋白1(PD-1)/程序性细胞死亡配体1(PD-L1)与多发性骨髓瘤关系的研究进展
Shimaa El-Garf,Reham Hammad,Eman Kandeel et al.
Shimaa El-Garf et al.
Background: The bone marrow microenvironment in multiple myeloma (MM) is characterized by complex immune dysregulation involving multiple inhibitory pathways. Among these, the programmed cell death protein 1 (PD-1)/progra...
Immune checkpoint crosstalk between LAG-3 and CD39/CD73 in glioblastoma: dual-pathway regulation of metabolic exhaustion and therapeutic reversal strategies [0.03%]
LAG-3和CD39/CD73在胶质母细胞瘤中的免疫检查点交叉对话：代谢耗竭的双通路调节及治疗逆转策略
Arpita Mukherjee
Arpita Mukherjee
Glioblastoma (GBM) represents an immunologically "cold" and metabolically suppressive tumor characterized by profound T-cell exhaustion, hypoxia-induced adenosinergic signaling, and resistance to checkpoint blockade. Converging evidence ide...
In-vitro effects of the urotensin-II peptide and its receptor antagonists on mcf-7 breast cancer cell line [0.03%]
乌拉斯坦-II肽及其受体拮抗剂对MCF-7乳腺癌细胞系的体外作用
Murat Olukman,Ezgi Olukman,Kutay Bulut et al.
Murat Olukman et al.
Background: Urotensin-II is a powerful vasoconstrictor peptide. Both the peptide and its receptor, GPR14, affect central nervous system, cardiovascular system, and kidney functions. Urotensin-II was found to be involved i...
The role of the microbiome in uterine cancer: insights into tumorigenesis, therapeutic implications, and clinical prospects [0.03%]
子宫癌中微生物组的作用：肿瘤发生、治疗意义及临床应用的启示
Yating Zhang,Xiaochuan Yu,Li Shi et al.
Yating Zhang et al.
Malignant tumors of the uterine cavity are a leading cause of cancer-related mortality in women worldwide. In recent years, the tumor microenvironment, as a novel biological concept, has garnered increasing attention. The microenvironment p...
Radiosensitizing effect of astaxanthin on radiation-induced cytotoxicity in breast cancer cells [0.03%]
虾青素对乳腺癌细胞放射增敏作用及机制研究
Bothaina Al-Awady,Abdel-Moneim Osman,Diana Hanna et al.
Bothaina Al-Awady et al.
Background: Radiotherapy (RT) is a primary treatment for cancer, including breast cancer, but its effectiveness is limited by severe side effects. Radiosensitization using natural products can enhance efficacy while reduc...
Cholecystectomy-associated gut microbiota dysbiosis promotes colorectal carcinogenesis: from epidemiological controversy to FXR-centered mechanistic insights [0.03%]
胆囊切除术相关肠道微生态失调促进结直肠癌发生：从流行病学争议到法尼醇受体介导的机制研究
Zhongqin Huang
Zhongqin Huang
Background and objective: Cholecystectomy is one of the most common surgeries worldwide, yet its association with colorectal cancer (CRC) risk remains controversial. Recent advances have linked gut microbiota and bile aci...
A real-world study of the effectiveness and safety of low-dose immunotherapy in addition to oral metronomic chemotherapy in recurrent and metastatic head and neck squamous cell carcinoma [0.03%]
低剂量免疫治疗联合口服节律化疗治疗复发和转移性头颈部鳞癌的疗效及安全性研究
Rushabh Kothari,Avinash Khadela,Gaurang Modi et al.
Rushabh Kothari et al.