A prospective development and evaluation of a 2D convolutional neural network-based auto-segmentation model for cervical cancer radiotherapy [0.03%]
一种基于二维卷积神经网络的宫颈癌放射治疗自动勾画模型的构建及评价
Sidharth Satish Menon,Mahak Gupta,Aakriti Bhardwaj et al.
Sidharth Satish Menon et al.
Background: Accurate delineation of target volumes and organs at risk (OAR) is essential in radiotherapy planning for cervical cancer. Deep learning (DL)-based auto-segmentation has the potential to improve contouring eff...
Global burden of multiple myeloma(1990-2021) and projections up to 2035: a methodical analysis leveraging the global burden of disease 2021 study and Mendelian randomization [0.03%]
多发性骨髓瘤的全球疾病负担（1990-2021）及至2035年的预测：基于全球疾病负担研究2021和孟德尔随机化的方法学分析
Run Qu,Xin Zhang,Jing Zou et al.
Run Qu et al.
Objective: Multiple myeloma (MM), being the second-most frequently occurring hematologic malignancy, is comprehensively assessed for its global disease burden and risk factors using the Global Burden of Disease (GBD) data...
Prospective evaluation of dose rate effects on acute radiation toxicities and quality of life in head and neck cancer [0.03%]
剂量率对头颈部肿瘤急性和生活质量影响的前瞻性评估研究
Ahmed Adel Ahmed,Wahib M Attia,O ELemary et al.
Ahmed Adel Ahmed et al.
Purpose: This study evaluates the influence of different dose rates on the radiation-related adverse events. Materials and methods: The...
Immune checkpoint inhibitors in advanced cholangiocarcinoma: a systematic review of efficacy, safety, and emerging biomarkers [0.03%]
晚期胆管癌免疫检查点抑制剂治疗的疗效、安全性及潜在生物标志物的系统评价
Faiz Un Nisa,Moeez Ali,Talha Khan et al.
Faiz Un Nisa et al.
Background: Cholangiocarcinoma (CCA) is an aggressive biliary tract malignancy often diagnosed at an advanced stage. For over a decade, gemcitabine-cisplatin (GemCis) remained the standard of care with limited survival be...
Silver-loaded nanoemulsion of Nepeta glomerulosa extract enhances cytotoxicity and induces apoptosis in A549 and AGS cancer cells [0.03%]
负载纳米乳制剂的唇形科glomerulosa提取物增强细胞毒性和诱导A549和AGS癌细胞凋亡
Sepideh Sahebi,Golaleh Mostafavi,Seyyedeh Mahdokht Maddah
Sepideh Sahebi
The global rise in cancer occurrence, together with the spread of multidrug resistance, highlights the critical demand for innovative treatment strategies. Nano-delivery approaches have emerged as promising solutions that enhance bioavailab...
Bidirectional mendelian randomization identifies plasma proteins associated with cervical cancer risk [0.03%]
双向孟德尔随机化识别出与宫颈癌风险相关的血浆蛋白
Yan-Hong Zhao,Qing-Fen Ruan,Jing-Hua Ning et al.
Yan-Hong Zhao et al.
Background: Cervical cancer continues to pose a considerable challenge to global health, necessitating innovative approaches for improved diagnostics and personalized treatment strategies. Prior investigations have sugges...
Decoding the functional landscape of long non-coding RNAs in hepatocellular carcinoma: molecular mechanisms, clinical implications, and therapeutic prospects [0.03%]
肝癌中长非编码RNA功能景观的解析：分子机制、临床意义及治疗前景
Humera Naveed,Zain-Ul Abidien,Kaleem Maqsood et al.
Humera Naveed et al.
Hepatocellular carcinoma (HCC) remains the third leading cause of cancer-related mortality worldwide, with limited treatment efficacy and poor prognosis, particularly in advanced-stage disease. Despite progress in diagnostic imaging and sys...
Navigating toxicity in lung cancer immunotherapy: challenges and advances in Nano medicine drug delivery [0.03%]
肺癌免疫治疗中的毒性及其纳米药物递送应对策略挑战与进展
Rishab Jain,Ananda Kumar Chettupalli,Sarad Pawar Naik Bukke et al.
Rishab Jain et al.
Lung cancer is still among the most malignant cancers, with immunotherapy becoming a ground-breaking treatment option. The ICIs and other immunotherapeutic drugs usually cause severe immune-related adverse effects curtailing their therapeut...
Wenbin Tan
Wenbin Tan
Objective: To systematically analyze the global research landscape, collaboration patterns, knowledge flow pathways, and frontier trends in the synergistic effects between the microbiome and cancer immunotherapy. ...
Tissue engineering driven regeneration in oral squamous cell carcinoma: from biomaterials to precision gene editing [0.03%]
组织工程驱动的口腔鳞状细胞癌再生：从生物材料到精确基因编辑
B Deva Darshinii,N Subhapradha,S Raghavi et al.
B Deva Darshinii et al.
Oral cancer is a significant global health challenge, ranking as the sixth most prevalent cancer worldwide, with approximately 377,000 new cases diagnosed annually. The high morbidity and mortality rates are largely attributed to tobacco an...