rol-6 and dpy-10C. elegans mutants have normal mitochondrial function after normalizing to delayed development [0.03%]
Rol-6和Dpy-10突变线虫的发育延迟表型不影响其线粒体功能
A Clare Sparling,Dillon E King,Joel N Meyer
A Clare Sparling
Collagen mutations are commonly used in the creation of Caenorhabditis elegans transgenic strains, but their secondary effects are not fully characterized . We compared the mitochondrial function of N2, dpy-10, rol-6, and PE255 C. elegans ....
sart-3 functions to regulate germline sex determination in C. elegans [0.03%]
sart-3调控秀丽隐杆线虫性别决定路径中的生殖细胞性别分化
Tokiko Furuta,Swathi Arur
Tokiko Furuta
Caenorhabditis elegans gene sart-3 was first identified as the homolog of human SART3 ( S quamous cell carcinoma A ntigen R ecognized by T -cells 3). In humans, expression of SART3 is associated with squamous cell carcinoma, thus most of th...
Characterization of the tilt (tt) phenotype in Drosophila melanogaster [0.03%]
模式生物果蝇中tt这一新性状的鉴定及初步分析
Arno Houtman,Samuel Gruber,Hailey Reisert et al.
Arno Houtman et al.
In the early 20th century, Calvin Bridges and Thomas Morgan identified a number of spontaneous mutations that displayed visible phenotypes in adult flies and subsequent analysis of these mutations over the past century have provided fundame...
François Bertaux,Istvan T Kleijn,Samuel Marguerat et al.
François Bertaux et al.
Steady-state cell size and geometry depend on growth conditions. Here, we use an experimental setup based on continuous culture and single-cell imaging to study how cell volume, length, width and surface-to-volume ratio vary across a range ...
First report of Tarantula-parasitic nematode Tarantobelus jeffdanielsi from Los Angeles, California [0.03%]
美国加利福尼亚州洛杉矶市首次报道狼蛛寄生线虫属的物种Tarantobelus jeffdanielsi n. sp.
Anil Baniya,Julie Ngov,Kyle Anesko et al.
Anil Baniya et al.
Tarantobelus jeffdanielsi is a recently described nematode parasite of tarantulas, originally isolated from a tarantula breeder in Virginia Beach, VA. We describe a new case of this parasite infecting tarantulas at a breeding facility in Lo...
Dry-freezing Steinernema carpocapsae infective juveniles for robust preservation of stocks [0.03%]
通过干燥冷冻异尖线虫侵染幼虫来稳健保存寄生线虫品种群
Patrick McClanahan,Tuan Anh Le,Bram Cockx et al.
Patrick McClanahan et al.
Cryopreservation allows strains to be stored, eliminating genetic drift and maintenance costs. Existing cryopreservation methods for the economically-important entomopathogenic nematode Steinernema carpocapsae involve multiple incubation an...
Agr Regulation of Streptococcal Pyrogenic Exotoxin A in Staphylococcus aureus [0.03%]
金黄色葡萄球菌对链球菌致热源性外毒素A的调控
Patrick Schlievert,Samuel Kilgore,Donald Leung
Patrick Schlievert
Group A streptococcal pyrogenic exotoxins (SPEs A, B, and C) are superantigens. SPE A shares high sequence similarity with Staphylococcus aureus enterotoxins (SEs) B and C. Since SPE A is bacteriophage-encoded, we hypothesized that its gene...
Conjugation and transposon mutagenesis of Xenorhabdus griffiniae HGB2511, the bacterial symbiont of the nematode Steinernema hermaphroditum (India) [0.03%]
Xenorhabdus griffiniae HGB2511（印度）的结合和转座子诱变，它是线虫Steinernema hermaphroditum的细菌内共生菌
Omar S Alani,Mengyi Cao,Heidi Goodrich-Blair et al.
Omar S Alani et al.
Symbiosis, the beneficial interactions between two organisms, is a ubiquitous feature of all life on Earth, including associations between animals and bacteria. However, the specific molecular and cellular mechanisms which underlie the dive...
Chemical Genetics Screen of EVP4593 Sensitivity in Budding Yeast Identifies Effects on Mitochondrial Structure and Function [0.03%]
化学遗传筛选酵母EVP4593敏感性鉴定出线粒体结构和功能的作用机制
Lexie Hiestand,Stella Shen,Willough Sloan et al.
Lexie Hiestand et al.
Mitochondria are essential eukaryotic organelles. Mitochondrial dysfunction can lead to mitochondrial myopathies and may contribute to neurodegenerative diseases, cancer, and diabetes. EVP4593, a 6-aminoquinazoline derivative with therapeut...
Low-Density Lipoprotein Receptor LRP-2 regulates GLR-1 glutamate receptors and glutamatergic behavior in C. elegans [0.03%]
低密度脂蛋白受体LRP-2通过调节C. elegans中的GLR-1谷氨酸受体控制谷氨酸相关行为
Bethany J Rennich,Eric S Luth,Julia Hofer et al.
Bethany J Rennich et al.
We identified the Low-Density Lipoprotein (LDL) Receptor Related Protein-2 (LRP-2) in a RNAi screen for genes that regulate glutamatergic behavior in C. elegans . lrp-2 loss-of-function mutants have defects in glutamatergic mechanosensory n...