Apoptotic pathway protein expression variance in metal oxide and quantum dot treated HeLa cells [0.03%]
金属氧化物和量子点处理的HeLa细胞中凋亡途径蛋白表达差异分析
Seth Harris,Kyoungtae Kim
Seth Harris
Using the HeLa cell line as a cancerous model, apoptotic protein expression was assessed upon various nanoparticle treatments. Utilizing a known chemotherapeutic agent, cisplatin, as a positive control for induction of apoptosis, several me...
Disruption of GRR1 in Saccharomyces cerevisiae rescues tps1Δ growth on fermentable carbon sources [0.03%]
Saccharomyces cerevisiae中破坏GRR1可使tps1Δ在发酵碳源上生长恢复正常
Anqi Chen,Patrick A Gibney
Anqi Chen
In Saccharomyces cerevisiae , trehalose-6-phosphate synthase (Tps1) catalyzes the formation of trehalose-6-phophate in trehalose synthesis. Deletion of the TPS1 gene is associated with phenotypes including inability to grow on fermentable c...
sut-2 loss of function mutants protect against tau-driven shortened lifespan and hyperactive pharyngeal pumping in a C. elegans model of tau toxicity [0.03%]
sut-2功能丧失型突变体通过保护秀丽隐杆线虫tau毒性模型中的tau驱动的缩短寿命和过度活跃的咽泵运动来发挥作用
Heather N Currey,Brian C Kraemer,Nicole F Liachko
Heather N Currey
Expression of human tau in C. elegans neurons causes progressive, age-associated loss of motor coordination, selective neurodegeneration, and shortened lifespan. Loss of function (LOF) mutations in the conserved gene sut-2 protects against ...
Jessica R Lucas,Brittany Dupree
Jessica R Lucas
Stomatal pores are adjustable microscopic holes on the surface of photosynthetic tissues that help regulate multiple aspects of plant physiology. Stomatal pores facilitate gas exchange necessary for photosynthesis, water transport, and temp...
Saccharomyces cerevisiae NRE1 and IRC24 Encode Paralogous Benzil Oxidoreductases [0.03%]
Saccharomyces cerevisiae NRE1和IRC24编码同源的苯甲酰羟基氧化还原酶
Brandon Garcia,Kasandra J Riley
Brandon Garcia
Irc24p is a benzil oxidoreductase encoded on chromosome IX of Saccharomyces cerevisiae . We identified a putative paralog, Nre1p, encoded 284 bp downstream. Both proteins are small, cytoplasmic, and are 52% identical (70% similar). PANTHER ...
Mutations in the NXF-1:NXT-1 mRNA export complex affect gene-expression driven by the hsp-16.41 promoter [0.03%]
NXF-1:NXT-1的突变影响hsp-16.41启动子驱动的基因表达及mRNA输出复合体的功能
Michael W Crawford,Galen Posch,Jerôme Cattin-Ortolá et al.
Michael W Crawford et al.
The NXF-1 : NXT-1 heterodimer is essential for the nuclear export of mRNA. Here we describe three new alleles of nxf-1 and one allele of nxt-1 isolated from a forward genetic screen. These mutations cause no apparent phenotype under normal ...
Gossypium hirsutum gene of unknown function Gohir.A03G0737001 encodes a potential Chaperone-like Protein of protochlorophyllide oxidoreductase (CPP1) [0.03%]
一个未知功能的Gossypium hirsutum基因Gohir.A03G0737001编码叶绿素原氧化还原酶(chlorophyllide oxidoreductase)辅助蛋白(CPP1)
Alana N Osborne,Andrew Osagiede,Amanda R Storm et al.
Alana N Osborne et al.
A gene of unknown function identified in Gossypium hirsutum , Gohir.A03G0737001.1, was studied using sequence and bioinformatic tools. The encoded protein (referred to here as GhCPP1-A0A1U8HKT6) was predicted to function as a Chaperone-like...
53bp1 mutation enhances brca1 and bard1 embryonic lethality in C. elegans [0.03%]
53BP1突变增强秀丽隐杆线虫BRCA1和BARD1的胚胎致死性
Sara Hariri,Qianyan Li,JoAnne Engebrecht
Sara Hariri
In mice, mutation of brca1 results in embryonic lethality, which is partially suppressed by 53bp1 mutation. In contrast, mutation of the C. elegans BRCA1 ortholog, brc-1 , or its binding partner, brd-1 , lead to only mild embryonic lethalit...
SHE9 deletion mutants display fitness defects during diauxic shift in Saccharomyces cerevisiae [0.03%]
∆SHE9突变株在Saccharomyces cerevisiae中经历二次利用期时表现出适应性缺陷
Shane J Kowaleski,Christina S Hurmis,Carvin N Coleman et al.
Shane J Kowaleski et al.
Saccharomyces cerevisiae protein She9 is localized to the inner mitochondrial membrane and is required for normal mitochondrial morphology. While deletion mutants of SHE9 ( she9Δ ) are viable and display large ring-like mitochondrial struc...
Complete sequences of conjugal helper plasmids pRK2013 and pEVS104 [0.03%]
完整的接合辅助质粒pRK2013和pEVS104的序列信息
Ashley Hall,Timothy Donohue,Jason Peters
Ashley Hall
We present the complete sequences of two commonly used conjugal helper plasmids: pRK2013 and pEVS104. These sequences will enable engineering of custom helper plasmids, for example, with different antibiotic markers or origins of replicatio...