Regulation of MAP Kinase signaling by the insulin-like growth factor pathway during C. elegans vulval development [0.03%]
胰岛素样生长因子信号通路在秀丽隐杆线虫 vulval 发育期间对 MAP 单一激酶信号通路的调节作用
Matthew Eroglu,W Brent Derry
Matthew Eroglu
Organ development depends on multiple signaling pathways working in concert to specify cell fates. Improper activity or inactivity of specific signaling pathways such as EGF-Ras-MAPK can lead to dedifferentiation and cancer. In C. elegans ,...
Genome characteristics of cluster EA Microbacterium bacteriophages HungryHenry, CaptainRex, and ChikPic isolated from soil in Tennessee [0.03%]
田纳西州土壤中噬菌体HungryHenry、CaptainRex和ChikPic的基因组特征
Sergei Markov,Clayton Barnes,Ariel Hensley et al.
Sergei Markov et al.
Bacteriophages HungryHenry, CaptainRex, and ChikPic were isolated from soil collected in Tennessee using the bacterium Microbacterium foliorum . These bacteriophages have genomes that are 41,516 bp, 39,941 bp, and 40,333 bp in length and en...
Bone morphogenetic protein 8B (BMP8B) increases the glucose sensitivity of ventromedial hypothalamus (VMH) glucose-inhibited (GI) neurons in female mice [0.03%]
骨形态发生蛋白8B(BMP8B)通过增加雌性小鼠腹内侧下丘脑血糖抑制型神经元的糖敏感性来促进摄食行为和体重增加
Pamela R Hirschberg,Munir Rahbe,Kevin Knapp et al.
Pamela R Hirschberg et al.
In female, but not male, mice, bone morphogenetic protein (BMP) 8B affects energy homeostasis by inhibiting AMP activated protein kinase (AMPK) in the ventromedial hypothalamus (VMH). VMH glucose-inhibited (GI) neurons that express neuronal...
A commonly used anti-SOX15 antibody fails to demonstrate specificity in mouse embryos [0.03%]
一种常用的抗SOX15抗体在小鼠胚胎中缺乏特异性
Farina Aziz,Bin Gu,Amy Ralston
Farina Aziz
SOX15 is a broadly conserved transcription factor involved in many critical processes, including mammalian cell fate specification and pluripotency. We investigated the specificity of a commercially available, polyclonal anti-SOX15 antibody...
SR Protein Kinase is expressed in Drosophila ovarian germline stem cells but is not essential for their self-renewal [0.03%]
泛素连接酶SRS6在卵泡发育中的功能研究
Victoria E Garrido,William G Outlaw,Amanda M Powell et al.
Victoria E Garrido et al.
Germline stem cells (GSCs) are necessary for oocyte production in Drosophila . GSC maintenance is regulated by intrinsic factors that promote their self-renewal. One such factor, the beta-importin, Transportin-Serine/Arginine rich , mediate...
Genome Sequence of Gordonia rubripertincta Phage DoobyDoo of the DV Cluster [0.03%]
DV簇Gordonia rubripertincta噬菌体DoobyDoo的基因组序列
Ibrahim Abdulrehman,Nathaly Angeles,Alexis Bostock et al.
Ibrahim Abdulrehman et al.
Novel bacteriophage DoobyDoo was isolated and characterized utilizing host Gordonia rubripertincta NRRL B-16540. DoobyDoo has a siphoviral morphology and a 66,343 bp genome with a GC content of 58.3%. The genome contains 97 protein coding g...
Biocultural conservation trail system reduces bryophyte richness but not diversity in the southernmost miniature forest of the world [0.03%]
生物文化保护小径系统减少了世界最南端微型森林的苔藓植物丰富度但没有减少其多样性
Morghan McCool,Clarissa Molina,Lucas Oyarzún Contreras et al.
Morghan McCool et al.
The Cape Horn region of southern Chile is one of the remaining bryophyte (mosses, liverworts, and hornworts) hotspots in the world. The Omora Ethnobotanical Park on Navarino Island contains impressive examples of the region's bryophyte dive...
Complete genome sequences of Rhodococcus equi phages CoffeeBean, Dorin, Francesca, Madraxi, and Tonitrus [0.03%]
Rhodococcus equi噬菌体CoffeeBean、Dorin、Francesca、Madraxi和Tonitrus的完整基因组序列
Orin R Daspit,Andrew C Slagter,Drew VanWoerkom et al.
Orin R Daspit et al.
We report genomes of five phages isolated using the actinobacterium Rhodococcus equi NRRL B-16538 . Based on gene content similarity, one phage is assigned to actinobacteriphage cluster CF, one to cluster CR, two to cluster CG, and one that...
rab-33 is not required for cuticle integrity in Caenorhabditis elegans [0.03%]
rab-33对_caenorhabditis_elegans_的外骨骼完整性并非必需条件
Emily Williams,Nico Pinzon,Grace Semrau et al.
Emily Williams et al.
Rab GTPases are master regulators of intracellular transport. We previously showed that a rab-6.2 deletion leads to a compromised cuticle, glycosylation defects, and increased axon regeneration. Mammalian orthologs of rab-6.2 and rab-33 hav...
Analysis of a cancer-associated mutation in the budding yeast Nuf2 kinetochore protein [0.03%]
酿酒酵母Nuf2染色体蛋白的一个与癌症相关的突变的分析
Angelica Andrade Latino,Sue Biggins
Angelica Andrade Latino
The kinetochore is a highly conserved megadalton protein complex that ensures proper chromosome segregation via microtubule attachments. The NDC80 complex is one of the major conserved microtubule binding complexes in the kinetochore. NUF2,...