gPPIpred: A User-Friendly PPI Predictor Based on Protein Molecular Graphs [0.03%]
基于蛋白质分子图的用户友好的PPI预测工具gPPIpred
Cleverson C Matiolli,Joana Marques,Isabel A Abreu
Cleverson C Matiolli
Protein-protein interactions (PPIs) govern essential cellular processes but remain challenging to characterize experimentally due to high cost and labor intensity. We present gPPIpred, a scalable computational framework leveraging graph neu...
Antimicrobial activity of Janthinobacterium, Pseudomonas , and Pseudoclavibacter bacterial soil isolates [0.03%]
芽囊链丝菌、节细菌和土壤分离细菌的抗菌活性
Kelena Snipes,Logan Angelillo,Julia Fugate et al.
Kelena Snipes et al.
Healthcare, and the world at large, are currently facing an antibiotic crisis caused by the increase in antibiotic resistant bacterial pathogens, combined with divestment in the drug discovery pipeline for new antibiotics. The Tiny Earth Pr...
Characterization of the Complete Genome of Arthrobacter globiformis Cluster FF Bacteriophage QuinnAvery [0.03%]
芽抱杆菌群FF菌株QuinnAvery噬菌体的全基因组特征分析
Elaine P Akst,Demelash Areda,Eric J Battaglioli et al.
Elaine P Akst et al.
Phage QuinnAvery produces turbid plaques in Arthrobacter globiformis B-2979 lawns, displays a siphovirus morphology, and is clustered with FF actinobacteriophages. The 43,177 bp genome of QuinnAvery is predicted to contain a tRNA-Arg(TCT) g...
Cynaropicrin inhibits pancreatic cancer cell viability and disrupts cellular redox homeostasis [0.03%]
苍术素抑制胰腺癌细胞活力和干扰细胞氧化还原稳态
Heather R Leek,Abby L Oberhelman,Sam R Rew et al.
Heather R Leek et al.
Pancreatic cancer accounts for approximately 8% of all cancer-related deaths. The compound cynaropicrin (CNP) has been investigated recently in several cancer models and has been shown to decrease cell viability. We used sulforhodamine B an...
Genome Sequences of Streptomyces griseus Phages Destructrice and Rikishi [0.03%]
灰链霉菌噬菌体Destructrice和Rikishi的基因组序列
Elizabeth A Powell,Allison O Wortman,Kathryn E Tyler et al.
Elizabeth A Powell et al.
This paper describes the complete genome sequences of two novel bacteriophages isolated using Streptomyces griseus . Destructrice is a podovirus bacteriophage with a 45,548 bp genome assigned to the actinobacteriophage cluster BF. In contra...
Long-term quantification and brief-pulse optogenetic perturbation of nucleocytoplasmic GtaC dynamics during Dictyostelium development [0.03%]
Dictyostelium发育过程中长时间量化和短暂脉冲光遗传扰动核质GtaC动态过程
Kensuke Yamashita,Tetsuya Muramoto
Kensuke Yamashita
Transcription factor nucleocytoplasmic dynamics play a key role in developmental gene regulation. In Dictyostelium , the transcription factor GtaC exhibits nucleocytoplasmic shuttling, but its shuttling trajectory across multicellular aggre...
Complete Genome Sequence of two Gordonia rubripertincta cluster CS4 Bacteriophages, Vitaenoii and Philon9 [0.03%]
两种戈登菌群CS4噬菌体Vitaenoii和Philon9的完整基因组序列
Joshua T McMenemy,Amanda I Acra,Elisabeth A Alexander et al.
Joshua T McMenemy et al.
We report the discovery and genome sequences of bacteriophages Vitaenoii and Philon9, isolated from soil samples collected in Durham, North Carolina using the host Gordonia rubripertincta NRRL B-16540. The phages have siphoviral morphology ...
Paige Alexander,Maggie Blair,Emma Boyen et al.
Paige Alexander et al.
Lethe, a predicted lytic bacteriophage with myovirus morphology, was isolated using Mycobacterium smegmatis mc²155 in North Georgia. Lethe has a genome of 155,828 base pairs with 230 predicted ORFs, 34 tRNAs, 1 tmRNA, and 64.70% GC content...
Carapics: A Web-based Platform for Semi-quantitative Analysis of Structural Change in Biological Samples [0.03%]
Carapics：一种用于分析生物样本结构变化的半定量web平台
Gary H Dickinson,Sejong Yoon,Nate Sorvino et al.
Gary H Dickinson et al.
Environmental stress can alter and damage biological structures with functional consequences. Inspired by observations of Tanner crabs after 2-year exposure to ocean acidification, we observed that crabs held at low pH appeared to have dama...
Valeria Dountcheva,Athanasios Bubulya,Labib Rouhana
Valeria Dountcheva
T/A cloning is a popular method for generating recombinant DNA plasmids. This method relies on single A:T nucleotide base pairs between PCR product ends and vector. Theoretically, the directionality of insert ligation with relation to the v...