Reem Elzaghir,Kailah C Collins,Alaa Abdulshafi et al.
Reem Elzaghir et al.
Minoxidil (MX) is a common treatment for androgenetic alopecia (AGA). While there are many proposed mechanisms through which MX may increase hair growth, a clear connection to sex-hormone pathways has yet to be established. With recent evid...
Development of A Spectrometric Enzyme-Coupled Assay for 11-Aminoundecanoic Acid Transaminase and Its Detection in Pseudomonas Strain JG-B Cell Lysate [0.03%]
用于十一氨基十一酸转氨酶的分光光度酶耦联测定法的发展及其在假单胞菌JG-B细胞裂解物中的检测
Sophia Yager-Motl,Lana Segizbayeva,Hisako Masuda
Sophia Yager-Motl
11-aminoundecanoic acid is a photochemical degradation product of the synthetic plastic nylon 11. With increasing plastic waste in the environment, understanding the fates of nylon 11 degradation product is important. Previously, a bacteria...
Klf2 as a potential regulator of the signaling Enos/Nhe3/Nherf2 axis in the early adaptive response to MSG-induced renal injury [0.03%]
Klf2作为调节MSG诱导的肾损伤早期适应性反应中的信号通路Enos/Nhe3/Nherf2轴的潜在调节因子
Itzel S Salmon-Cabrales,Luis M Palomino Martínez,Gerardo R Padilla-Rivas et al.
Itzel S Salmon-Cabrales et al.
Oxidative stress-induced renal impairment can result from an overconsumption of monosodium glutamate (MSG). In this context, we analyzed the expression of Krüpple-like factors (KLFs) to identify regulators of ionic homeostasis. Our results...
Gap junctional communication in the intestine affects social feeding behavior via FLP-21 and the NPR-1 mediated signaling pathway [0.03%]
肠道连接蛋白通讯通过FLP-21和NPR-1介导的信号通路影响社交摄食行为
Lisa Calabro,Maureen Peters
Lisa Calabro
Communication between the gut and the nervous system coordinates aspects of behavior and responses to stressors. When actively feeding, C. elegans executes a digestive motor program triggered by a calcium wave that requires gap junctional ...
Genome Sequence and Host Range Investigation of Cluster CV Phage Spink [0.03%]
Spink噬菌体的基因组序列及宿主范围研究
Ethan Smith,Ailanys E Cordero-Morales,Elizabeth Padilla-Crespo et al.
Ethan Smith et al.
Bacteriophage Spink was isolated using host bacterium Gordonia terrae 3612. Spink's host range was investigated across six other bacterial strains; however, its host range appeared restricted to G. terrae , as all expansion host pairings re...
The Drosophila l(3)tb mutant as a model to study stress-inducible Hsp70-expressing brain tumor [0.03%]
用于研究应激诱导的Hsp70表达性脑肿瘤的果蝇l(3)tb突变体模型
Abhijit Biswas,Devanjan Sinha
Abhijit Biswas
Brain tumors remain among the most aggressive cancers due to their ability to adapt to microenvironmental stress to sustain malignancy and resist therapy. We propose Drosophila lethal(3) tumorous brain [ l(3)tb ] mutant, which develops rapi...
Identification of Drosophila melanogaster Strain-Specific Sequence Variations in the Nepl15 Transcript of Oregon-R relative to FlyBase Data [0.03%]
通过与Flybase数据库比较鉴定模式生物果蝇Oregon-R品系Neprilysin 15基因转录本的序列特异性差异
Chase Drucker,Surya Jyoti Banerjee
Chase Drucker
According to FlyBase, the Drosophila melanogaster (fruit fly) Neprilysin-like 15 (Nepl15) gene has only one annotated transcript and a 686-amino acid-long protein. However, Nepl15 transcripts exhibit organ- and sex-specific differential exp...
Screening Atg11, a central organizer of yeast selective autophagy, for residues involved in the Atg11-Atg9 interaction [0.03%]
筛选参与Atg11-Atg9相互作用的Atg11残基：Atg11是酵母选择性自噬的核心组织者
Chimi Dolker Sherpa,Patricia Woghiren,Erin Leonello et al.
Chimi Dolker Sherpa et al.
The yeast protein Atg11, whose structure is not fully solved, is a central organizer of autophagosome formation that recruits Atg9 during selective autophagy. Although the residues in Atg9 responsible for this interaction are known, those i...
Senescent-associated β-galactosidase accumulation does not correlate with lifespan in different strains of Nothobranchius furzeri but does respond to intermittent fasting to extend lifespan [0.03%]
无尾粘贴鱼不同品系的衰老相关β-半乳糖苷酶积累与寿命无关，但能响应间歇性禁食以延长寿命
Israel Akinrotimi Akinola,Tyrone Genade
Israel Akinrotimi Akinola
Senescent cell (SC) accumulation theoretically causes aging-related tissue malfunction. We examined SC burden in short-lived and long-lived Nothobranchius furzeri fish strains, and fasting's effects on SCs. Despite different lifespans, SC a...
Microinjected dsRNA triggers a robust RNAi response in Stentor coeruleus [0.03%]
微量注射的dsRNA可触发粗大变形虫中的高效RNA干扰反应
Makenna Kuecks,Preeti Arra,Sarah Hoffmann-Weitsman et al.
Makenna Kuecks et al.
Stentor coeruleus is an emerging model system for the study of morphogenesis and regeneration as well as behaviors like habituation and photosensation. While Stentor 's genome has been sequenced, genetic tools are currently limited to RNA i...