Neurod2 knockdown in Xenopus laevis tadpole brain retains cells in a proliferating, progenitor-like state [0.03%]
Xenopus laevis蝌蚪脑中神经干细胞基因Neurod2被敲低后细胞处于增殖的、类似干细胞的状态
Caroline W Beck,Sulagna Banerjee,Robert C Day
Caroline W Beck
Neurogenic differentiation factor 2, encoded by the NEUROD2 gene, is a proneural transcription factor required for neuronal differentiation and survival. Haploinsufficiency of NEUROD2 can cause neurodevelopmental disorders with or without s...
Wormtrails: a python package for viewing C. elegans movement [0.03%]
Wormtrails：用于查看秀丽隐杆线虫运动的 Python 包
Christopher Dante Ashih,Yuyan Xu,Javier Apfeld
Christopher Dante Ashih
Wormtrails is a python package designed to create images and videos depicting the motion of C. elegans on solid media. Darkfield or brightfield images may be converted into stills or movies, with time encoded by color. This package was prim...
Variable deep learning training horizons reveal the temporal complexity of biological systems [0.03%]
可变深度学习训练地平线揭示了生物系统的时空复杂性
Po-Hao Chiu,Jacob I Evarts,Patrick Feng et al.
Po-Hao Chiu et al.
The increasing quantity of time-series images presents new opportunities for extracting biological insights from data. Here, we introduce a deep learning framework with a variable input sequence length to predict cell and colony morphologie...
Neha Tiwari,Madhu Tapadia
Neha Tiwari
Endoreplication drives polyploidy in metabolically active epithelial tissues. Here we show that loss of Drosophila Tau increases nuclear size and DAPI fluorescence in principal and stellate cells of the Malpighian tubule, indicative of elev...
The conserved microtubule-associated protein Mini Spindles promotes dendrite branching and limits terminal branch elongation in Drosophila class III and IV dendritic arborization neurons [0.03%]
保守的微管相关蛋白Mini Spindles促进果蝇III类和IV类树突神经元的树突分支并限制末端分支的伸长
Claire Kittock,Noor Anvery,Mala Misra
Claire Kittock
Microtubule dynamics influence neuron morphogenesis. We investigated the role of the conserved microtubule-associated protein Mini Spindles (Msps) in the morphogenesis of branched dendrite arbors using Drosophila melanogaster larval class I...
Extending Biopython to combine multiple sequence alignments with the same reference into a Multiple Sequence Alignment [0.03%]
扩展Biopython以结合具有相同参考的多个序列对齐结果为多序列对齐结果
Cassia Bastress,Michiel de Hoon,Manuel Lera-Ramirez et al.
Cassia Bastress et al.
Pairwise alignments (PWAs) are commonly used to compare sequences to a reference. Existing alignment tools provide algorithms to align multiple sequences to a single reference and to merge two sets of aligned sequences; but not to combine i...
Simulated drought with Polyethylene-Glycol (PEG) decreases above-ground performance and increases nodulation in the legume Medicago lupulina [0.03%]
聚乙二醇模拟干旱降低牻牛儿苗属植物黄花苜蓿的地上部表现，增加其根部结瘤现象
Hana Cho,Emily Glasgow,Valmic Mukund et al.
Hana Cho et al.
We investigated drought growth responses in Medicago lupulina using PEG to simulate drought stress. We grew Medicago lupulina plants inoculated with Sinorhizobium meliloti in Magenta boxes under randomly assigned treatments: a control, PEG ...
Using Experimental Evolution to Correct Mother-Daughter Separation Defects in Brewing Yeast [0.03%]
利用实验进化来纠正啤酒酵母的母细胞和子细胞分离缺陷
Lauren M Ackermann,Amanda Ro,Barbara Dunn et al.
Lauren M Ackermann et al.
Brewers have domesticated many strains of Saccharomyces cerevisiae with traits complementary to different beers, but these strains may also harbor undesirable characteristics. One example is the mother-daughter separation defect (MDSD) whic...
Basia Love,Jeffrey K Conner,Emily B Josephs et al.
Basia Love et al.
Climate change is increasing average temperature and decreasing water availability, both stressors that affect plant growth. High heat consistently decreases growth rate but plants may grow rapidly to escape drought or grow more slowly and ...
Salinity stress reduces tree reproductive allocation in coastal forests [0.03%]
盐胁迫降低了沿海森林木本植物的生殖分配比例
Juan Ignacio Martínez,Aliya Khan,Keryn Gedan
Juan Ignacio Martínez
Plants adjust reproductive allocation in response to environmental changes to maximize fitness. As sea level rise increases salinity in coastal forests, we examined its effects on seed rain in two tree species. Pinus taeda showed a median 5...