Aberrant expression of MAPK1 and MCTS1 in chronic myeloid leukemia (CML) [0.03%]
MAPK1和MCTS1在慢性髓性白血病中的异常表达
Leo Kortendick,Corinna Meyer,Stefan Nagel
Leo Kortendick
Genomic amplification may result in aberrant gene expression and support development of cancer, including chronic myeloid leukemia (CML). In CML cell line K-562, we recently reported overexpression of TBX1 located at chromosomal position 22...
Starvation-Induced Disruption of Nocturnal activity in the tropical house cricket, Gryllodes sigillatus [0.03%]
starvation诱导的热带家用蟋蟀Gryllodes sigillatus夜行性行为紊乱
Hugo Moebel,Eshani Yeragi,Isaac Jones et al.
Hugo Moebel et al.
Feeding state potently modulates foraging behavior and locomotor activity. Here, we examined activity patterns across developmental stages in the nocturnal tropical house cricket or banded cricket, Gryllodes sigillatus . Adult males and fem...
Exclusion of the endoplasmic reticulum from the C. elegans meiotic spindle controls spindle size [0.03%]
线虫细胞器排除机制控制纺锤体大小
Alma Aquino,Francis McNally
Alma Aquino
The nuclear envelope is composed of sheet-like ER that separates chromatin from tubulin during interphase. During oocyte maturation in C. elegans , a fenestrated envelope of sheet-like ER continues to envelope the meiotic spindle through me...
The chromosome complement of male Chrysoperla rufilabris (Burmeister, 1839), with evidence of distance segregation in meiosis I [0.03%]
Chrysoperla rufilabris (Burmeister, 1839)雄虫的染色体组成及其减数第一次分裂中距离分离的证据
Valoria Maslin,Allison Eisenhauer,Leocadia Paliulis
Valoria Maslin
Neuropteran insects display a phenomenon called distance segregation during male meiosis I, where the X and Y chromosomes are unconnected from prometaphase I through anaphase I. Here we investigate chromosome number and patterns of chromoso...
Melissa M Mailhot,Jesse G Jones,Dylan L Castro et al.
Melissa M Mailhot et al.
Across species, Epidermal Growth Factor (EGF) family ligands and their receptors participate in developmental and physiological cell-cell signaling events. C. elegans possesses a single EGF receptor, LET-23 /EGFR, and two characterized EGF ...
Validating and Optimizing a Drosophila Larval Model of Parkinson's Synucleopathy [0.03%]
帕金森病α-突触核蛋白病理的小鼠模型的验证与优化
Sarah Perry,Nicholas More
Sarah Perry
Parkinson's disease (PD) is a prevalent neurodegenerative disorder with complex genetic and environmental underpinnings. Misexpression of human alpha-synuclein (αSyn) in Drosophila larval dopaminergic neurons has been shown to induce PD-li...
Reduced insulin-like signaling restores motor and chemosensory neuron function in C. elegans expressing TDP-43, an ALS-associated protein [0.03%]
低胰岛素信号转导可恢复TDP-43致病蛋白表达线虫中的运动和化学感觉神经元功能
Vincent Lotesto,Cindy Voisine
Vincent Lotesto
TAR DNA-binding Protein 43 (TDP-43) is linked to the pathology of neurodegenerative diseases. We used the roundworm Caenorhabditis elegans to examine the neurotoxic impact of the pan-neuronal expression of wild-type human TDP-43 (hTDP-43) f...
The Immunoglobulin Domain of SISS-1/EGF is Required for its Function [0.03%]
SISS-1/EGF的免疫球蛋白结构域对其功能是必需的
Jesse G Jones,Cheryl Van Buskirk
Jesse G Jones
Epidermal growth factor (EGF) signaling plays roles in development and physiology across the animal kingdom. In the nematode C. elegans , a single EGF receptor (EGFR) and two EGF family ligands have been characterized. LIN-3 /EGF is require...
Graham M Jones,Natalie Ball,Alejandra Moreno et al.
Graham M Jones et al.
Presenting a gene model for the ortholog of multiple inositol polyphosphate phosphatase 2 ( Mipp2 ) in the May 2017 (Princeton ASM75419v2/DsimGB2) Genome Assembly (GenBank Accession: GCA_000754195.3 ) of Drosophila simulans . This ortholog ...
Gene model for the ortholog of dock in Drosophila ananassae [0.03%]
Drosophila ananassae的dock直向同源基因模型
Anne E Backlund,Tamica D&#x;Souza,Jaskamaldip Kaur et al.
Anne E Backlund et al.
Gene model for the ortholog of dreadlocks ( dock ) in the May 2011 (Agencourt dana_caf1/DanaCAF1) Genome Assembly (GenBank Accession: GCA_000005115.1 ) of Drosophila ananassae . This ortholog was characterized as part of a developing datase...