glorund functions in the Drosophila intestine to regulate triglyceride storage and the expression of lipid transport protein genes [0.03%]
果蝇肠道中的Glorund通过调节甘油三酯的储存及脂质转运蛋白基因的表达来控制脂肪酸摄取
Roman Voskoboynikov,Justin R DiAngelo
Roman Voskoboynikov
The intestine acts as the primary site for absorption of dietary lipids. These lipids are packaged and transported via lipoprotein complexes, whose altered levels correlate with metabolic disease. The Drosophila splicing factor glorund (gl...
Reduced expression of the electron transport chain component ATPsynβL in glutamate neurons changes Drosophila melanogaster sleep patterns through adulthood [0.03%]
线粒体电子传递链组分ATPsynβL在谷氨酸能神经元中的表达量降低可改变果蝇成年期的睡眠模式
Abigail Forrest,Maria Longenecker,Marciella V Shallomita et al.
Abigail Forrest et al.
A physiological marker of human aging is a decline in sleep patterns, a behavior also found in Drosophila melanogaster . To understand the connection between aging and sleep, we monitored sleep in long-lived flies. RNAi targeting the electr...
Cyanobacterial Bloom and Toxin Identification in Austin, TX, USA Creeks [0.03%]
美国德克萨斯州奥斯汀市溪流中蓝藻水华与毒素的鉴定
Hanan Brower,Sahar Mahmood,Joana Ruiz-Escobar et al.
Hanan Brower et al.
Cyanobacterial harmful algal blooms (cyanoHABs) can form in freshwater, and their toxins are harmful to flora and fauna, including humans. To assess the extent of cyanoHABs in urban waterways, seven creeks and Lady Bird Lake in Austin, TX U...
Stress-associated High Production of Large Extracellular Vesicles in the Parent Generation is Not Inherited by C. elegans F1 Progeny [0.03%]
压力相关的大量细胞外囊泡的产生不会在秀丽隐杆线虫亲本和其后代之间传递
Guoqiang Wang,Anna Joelle Smart,Jason F Cooper et al.
Guoqiang Wang et al.
Parental stress can influence stress responses in offspring. In C. elegans neurons, proteostress can induce the extrusion of aggregates and organelles in large extracellular vesicles called exophers. Under mild proteostress, ~20% of ALMR ...
The N-terminal α helix domain of the mitochondrial VDAC protein Por2 is dispensable for promoting the nuclear localization of yeast AMPK [0.03%]
线粒体电压依赖性阴离子通道蛋白Por2的N端α-螺旋结构域对于酿酒酵母AMPK核定位是非必需的
Kerry Brown,Hemanth Singuluri,Frank Perkins et al.
Kerry Brown et al.
In yeast, the mitochondrial voltage-dependent anion channel (VDAC) proteins Por1 and Por2 play regulatory roles in the regulation of Snf1, an ortholog of AMP-activated protein kinase (AMPK). An important question is whether Por1 and Por2 se...
Neurod2 knockdown in Xenopus laevis tadpole brain retains cells in a proliferating, progenitor-like state [0.03%]
Xenopus laevis蝌蚪脑中神经干细胞基因Neurod2被敲低后细胞处于增殖的、类似干细胞的状态
Caroline W Beck,Sulagna Banerjee,Robert C Day
Caroline W Beck
Neurogenic differentiation factor 2, encoded by the NEUROD2 gene, is a proneural transcription factor required for neuronal differentiation and survival. Haploinsufficiency of NEUROD2 can cause neurodevelopmental disorders with or without s...
Wormtrails: a python package for viewing C. elegans movement [0.03%]
Wormtrails：用于查看秀丽隐杆线虫运动的 Python 包
Christopher Dante Ashih,Yuyan Xu,Javier Apfeld
Christopher Dante Ashih
Wormtrails is a python package designed to create images and videos depicting the motion of C. elegans on solid media. Darkfield or brightfield images may be converted into stills or movies, with time encoded by color. This package was prim...
Variable deep learning training horizons reveal the temporal complexity of biological systems [0.03%]
可变深度学习训练地平线揭示了生物系统的时空复杂性
Po-Hao Chiu,Jacob I Evarts,Patrick Feng et al.
Po-Hao Chiu et al.
The increasing quantity of time-series images presents new opportunities for extracting biological insights from data. Here, we introduce a deep learning framework with a variable input sequence length to predict cell and colony morphologie...
Neha Tiwari,Madhu Tapadia
Neha Tiwari
Endoreplication drives polyploidy in metabolically active epithelial tissues. Here we show that loss of Drosophila Tau increases nuclear size and DAPI fluorescence in principal and stellate cells of the Malpighian tubule, indicative of elev...
The conserved microtubule-associated protein Mini Spindles promotes dendrite branching and limits terminal branch elongation in Drosophila class III and IV dendritic arborization neurons [0.03%]
保守的微管相关蛋白Mini Spindles促进果蝇III类和IV类树突神经元的树突分支并限制末端分支的伸长
Claire Kittock,Noor Anvery,Mala Misra
Claire Kittock
Microtubule dynamics influence neuron morphogenesis. We investigated the role of the conserved microtubule-associated protein Mini Spindles (Msps) in the morphogenesis of branched dendrite arbors using Drosophila melanogaster larval class I...