Lucas Tang,Aseel AlKaabi,Damon Meyer
Lucas Tang
Saccharomyces cerevisiae has several unique open reading frames that contribute to overall fitness. This study examined ICS3 , a contributor of Cu 2+ homeostasis. Our results successfully replicate previous work by the Monteiro laboratory u...
Y45G5AL.1 is a potential Kinesin-1 Interacting Protein on the Surface of Yolk Granules [0.03%]
Y45G5AL.1可能是蛋黄颗粒表面结合的动力蛋白-1相互作用蛋白
Denisa Lazureanu,Francis McNally
Denisa Lazureanu
In C. elegans , kinesin/ KCA-1 on the surface of yolk granules is thought to drive outward migration of the meiotic spindle by transporting membranous organelles inward on microtubules with minus ends at the cortex. Here we used BioID to id...
Biological significance of sperm-independent calcium oscillations in immature oocytes of mice [0.03%]
小鼠未成熟卵母细胞中与精子无关的钙离子振荡的生物学意义
Sae Horiike,Woojin Kang,Minoru Ichinose et al.
Sae Horiike et al.
Sperm-independent Ca 2+ oscillations are induced in immature oocytes, and presumably contribute to oocyte quality; however, its physiological role remains unclear. We studied the significance of Ca 2+ oscillations in ovarian functions using...
The immunoglobulin domain of C. elegans IGEG-2/EGF is required for its function [0.03%]
线虫IGEG-2/表皮生长因子的免疫球蛋白结构域对其功能是必需的
Darlene Mendez,Marine Barsegyan,Cheryl Van Buskirk
Darlene Mendez
Epidermal Growth Factor (EGF) family ligands mediate signaling events in development and physiology across species. These ligands are transmembrane proteins that undergo ectodomain shedding to release the soluble EGF domain, which mediates ...
Ce -NeRV3D - a C. elegans Neuron RNA-seq Visualization tool in 3D [0.03%]
Ce -NeRV3D - 一个用于三维可视化秀丽隐杆线虫神经元RNA测序的工具
Luca Golinelli,Majdulin Nabil Istiban,Jan Watteyne et al.
Luca Golinelli et al.
Caenorhabditis elegans provides a tractable model for neural circuit studies, with complete connectomes and single-cell transcriptomic atlases available. Here, we present Ce -NeRV3D ( C. elegans Neuron RNA-seq Visualization tool in 3D), a B...
Autism risk variants in DLG4 ortholog increase penetrance of uncommon individual behavioral trait in Caenorhabditis elegans [0.03%]
自闭症风险变异在DLG4同源物中增加秀丽隐杆线虫罕见个体行为特征的易感性
Grace Wulffraat,Lauren Rosta,Paula Hernández et al.
Grace Wulffraat et al.
Autism is a largely neurogenetic condition characterized by atypical behaviors, including increased prevalence of motor stereotypies. We used Caenorhabditis elegans to model the T611I variant in the DLG4 ortholog dlg-1 . During phenotyping,...
Synthetic Manihot esculenta Rubisco activase proteins with increased thermotolerance identified via machine learning [0.03%]
基于机器学习鉴定的热稳定性增强的木薯Rubisco活化酶合成蛋白
Clayton Dilks,Rhiannon LaVine,Claire Buchanan et al.
Clayton Dilks et al.
Adaptation to increasing environmental temperatures is essential to plant survival and human food production. Thermal tolerance is controlled by a complex network of factors in plants including but not limited to genetic variation and envir...
The protein-protein interaction between two spliced leader trans -splicing factors is mediated by two interlinked α-helical domains [0.03%]
两个拼接引导转-splicing因子之间的蛋白-蛋白相互作用由两个相连的α-螺旋结构域介导
Peter Eijlers,Jonathan Pettitt,Berndt Müller
Peter Eijlers
SNA-1 and SNA-2 proteins are involved in spliced leader trans -splicing in Caenorhabditis elegans . They are components of the SL1 snRNP that donates the spliced leader 1 RNA which replaces the 5' end of most pre-mRNAs. SNA-1 and SNA-2 bind...
Bisphenol S impairs courtship, grooming, and locomotor behaviors in Drosophila melanogaster [0.03%]
双酚S通过干扰果蝇的求偶、梳妆和运动行为而影响其行为表现
Zubair Mahyar,Connor Spann,Chloe J Welch et al.
Zubair Mahyar et al.
Bisphenol S (BPS), a common substitute for bisphenol A (BPA) in "BPA-free" products, is a potential developmental neurotoxicant. To investigate the developmental consequences of BPS exposure, we used Drosophila melanogaster as a model organ...
A 300 bp non-coding repeat sequence has co-evolved with the ced-2/CRKII-set-23/SETMAR genes of nematodes [0.03%]
一个300个碱基对的非编码重复序列与线虫的ced-2/crkk和set-23/setmar基因共同进化
Yeshaswi Pulijala,Victoria Brown,Martha Soto
Yeshaswi Pulijala
Highly conserved non-coding repeats may encode sequences with regulatory functions. We report a ~300 nucleotide non-coding repeat found four times in C. elegans , and exclusively at the ced-2 /CRKII- set-23 /SETMAR operon. Comparative analy...