Mitochondrial polarization and redox homeostasis couple glycolysis-to-OXPHOS metabolic rewiring to lifespan extension in C. elegans [0.03%]
线粒体去极化和氧化还原稳态通过寿命worm耦合糖酵解至三羧酸循环的代谢重排
Anwaar Ali,Shanmuganathan Balakrishnan,Jiayu Xiang et al.
Anwaar Ali et al.
Mitochondria are essential for maintaining cellular homeostasis throughout life. Here, we investigated the differential effects of glucose and galactose, as well as glycolytic inhibition, on C. elegans lifespan in relation to mitochondrial ...
Cysteine rich intestinal protein 2 links copper homeostasis to translational regulation in primary myoblasts [0.03%]
半胱氨酸丰富的肠蛋白2在原发性肌管中的铜稳态和翻译调节之间的关联作用
Odette Verdejo-Torres,Teresita Padilla-Benavides
Odette Verdejo-Torres
Copper (Cu) is an essential trace element for cellular metabolism, yet its roles in development are not fully defined. We identified murine cysteine-rich intestinal protein 2 (mCrip2) as a novel Cu-binding protein required for myoblast diff...
AgBioDatabase Finder: an online tool to help researchers find and submit agricultural genomic, genetic, and breeding data [0.03%]
AgBioDatabase Finder：一个在线工具，可帮助研究人员查找和提交农业基因组、遗传和育种数据
Leyla Cabugos,Katheryn Buble,Jenna Daenzer et al.
Leyla Cabugos et al.
To improve the FAIRness of agricultural genomic, genetic, and breeding ( GGB ) data, the AgBioData FAIR Scientific Literature Working Group developed a free search tool that helps researchers identify appropriate databases for submitting th...
Genome Sequences of Cluster A Mycobacteriophages Dorothea and LappelDuVide, Isolated on Mycobacterium smegmatis mc 2 155 [0.03%]
麦氏分枝杆菌(Dorothea和LappelDuVide菌株)A群分枝杆菌噬菌体基因组序列测定分析
Nicole Pasterczyk,Claire Wilson,Zoe Broker et al.
Nicole Pasterczyk et al.
Genome annotation of Mycobacterium smegmatis phages Dorothea and LappelDuVide revealed genomic features/organization common to cluster A mycobacteriophages; they are assigned to subclusters A6 and A4, respectively. Both genomes encode a put...
Measurement of NAD(H) concentration using BCA dye and applications to assays of dehydrogenases [0.03%]
利用BCA染料测定NAD(H)浓度及其在脱氢酶活性检测中的应用
Umanga Rupakheti,Derian Andrew,Sara E Scanlan et al.
Umanga Rupakheti et al.
Dehydrogenases are a widespread enzyme family that play essential roles in all metabolic processes. We observe that one of the substrates of many dehydrogenases, the coenzyme NAD(H), reacts with copper in the bicinchoninic acid assay to pro...
Zoe A Long,Benjamin S Ramage
Zoe A Long
Commercial potting soil mixes are typically dominated by peat moss, a nonrenewable resource. Here, we explore the potential of a novel alternative growth medium: dog fur waste collected from retail grooming salons. We evaluated three common...
Null Mutant mig-15(udn323) Shows Touch Receptor Neuron Migration Defects in C. elegans [0.03%]
芽胞突变体mig-15(udn323)导致秀丽隐杆线虫感觉神经元迁移缺陷
Sara DaCunha,Gary A Silverman,Tim Schedl et al.
Sara DaCunha et al.
The C. elegansmig-15 gene is an essential driver of Q-neuroblast polarization and migration. mig-15 mutations alter the migration of Q-neuroblast descendants. However, the effects of complete loss-of-function of mig-15 on C. elegans Touch R...
The Microbiota of Homemade Tepache Includes Antibiotic-Resistant Microorganisms [0.03%]
家庭自制塔帕奇中的微生物群包含耐抗生素微生物
Timothy Allshouse,Myleen Amendano,Becky Caruso et al.
Timothy Allshouse et al.
Tepache is a traditional, homemade Mexican drink made by fermenting pineapple rinds. The natural probiotic bacteria in tepache are said to promote a healthy gut microbiome. This study assessed the microbial community in homemade tepache for...
Savannah E Sojka,Fletcher M Hammond,Denise M Ferkey
Savannah E Sojka
Cyclic nucleotides (cAMP, cGMP) are critical second messengers that transduce diverse signaling events within cells, ranging from developmental processes and neuronal signaling to roles in cellular growth (Fajardo et al., 2014; Galande & Co...
GABA A α4 is expressed in cerebrospinal fluid-contacting neurons and regulates swim behavior in developing zebrafish [0.03%]
GABA A α4表达于接触脑脊液的神经元中并调控发育斑马鱼的游泳行为
Wayne Barnaby,Sydney O&#x;Malley,Gerald B Downes
Wayne Barnaby
GABA A receptors are present in hindbrain and spinal cord networks, playing a pivotal role in regulating locomotion. In this study, we demonstrate that mutations in the gabra4 gene, which encodes the α4 subunit of GABA A receptors, result ...