An nhr-23::mScarlet::3xMyc knock-in allele for studying spermatogenesis and molting [0.03%]
nhr-23::mScarlet::3xMyc基因敲入等位基因在研究精子发生和蜕皮中的应用
Krista M Myles,James Matthew Ragle,Jordan D Ward
Krista M Myles
C. elegans NHR-23 is a nuclear hormone receptor transcription factor involved in molting, apical extracellular matrix structure, and spermatogenesis. To determine NHR-23 expression dynamics, we previously tagged the endogenous nhr-23 locus ...
MET exon 14 skipping is overexpressed in an allele-specific manner in lung adenocarcinoma primary samples [0.03%]
肺癌原发样本中MET外显子14跳读的等位基因特异性过表达现象
Megan Durham,Swetha Vadde,Angela N Brooks
Megan Durham
MET exon 14 skipping ( METΔ14 ) is a well-characterized oncogene in the Ras-MAPK pathway driving lung adenocarcinoma (LUAD). Previous studies on METΔ14 revealed this aberrantly spliced oncogene is expressed in LUAD primary samples and is ...
Exposure to valproic acid (VPA) reproduces hdac1 loss of function phenotypes in zebrafish [0.03%]
丙戊酸钠致斑马鱼 Hdac1 缺失功能表型的研究
Alec A Jones,Terence Willoner Jr,Lacie Mishoe Hernandez et al.
Alec A Jones et al.
Histone deacetylases are enzymes that remove acetyl groups from histone tails and are understood to act as repressors of transcriptional activity. Hdac1 has been previously shown to function in eye, pectoral fin, heart, liver, and pharyngea...
Gossypium hirsutum gene of unknown function, Gohir.A02G039501.1, encodes a potential DNA-binding ALOG protein involved in gene regulation [0.03%]
一个未知功能的陆地棉基因Gohir.A02G039501.1 编码一种潜在的DNA结合ALOG蛋白并参与基因调控
Jonathan Zirkel,Amanda M Hulse-Kemp,Amanda R Storm
Jonathan Zirkel
A protein of unknown function encoded by gene Gohir.A02G039501.1 in Gossypium hirsutum , was studied using sequence and structure bioinformatic tools leading to its proposed function as a nuclear, DNA-binding ALOG protein involved in gene r...
CP110 and CEP135 localize near the proximal and distal centrioles of cattle and human spermatozoa [0.03%]
牛和人类精子中的CP110和CEP135定位于近端中心体和远端中心体附近
Katerina A Turner,Drew L Caswell,Bryce M McGrady et al.
Katerina A Turner et al.
Centrosomes play an important role in the microtubule organization of a cell. The sperm's specialized centrosome consists of the canonical barrel-shaped proximal centriole, the funnel-shaped distal centriole, and the pericentriolar material...
The nematode parasite Steinernema hermaphroditum is pathogenic to Drosophila melanogaster larvae without activating their immune response [0.03%]
线虫寄生虫Steinernema hermaphroditum可以致病果蝇幼虫而不会激活其免疫反应
Tien Huynh,Damien OHalloran,John Hawdon et al.
Tien Huynh et al.
Entomopathogenic nematodes are commonly used to control insect pest populations in the field. They also contribute substantially to understanding the molecular basis of nematode pathogenicity and insect anti-nematode immunity. Here, we test...
Tia M Ariagno,John S Smetana,Christopher W Lennon
Tia M Ariagno
Inteins excise themselves from precursor polypeptides through protein splicing, joining N- and C-exteins with a peptide bond. Split inteins are expressed as separate polypeptides that undergo protein trans splicing (PTS). Here, we demonstra...
An easy and inexpensive method for determining the rate of individual phoretic events of nematodes [0.03%]
一种测定线虫个体 hitchcock事件速率的简便经济的方法
Benjamin Williams,Matthew Nelson,Scott McRobert et al.
Benjamin Williams et al.
Considering their limited locomotory capabilities, the cosmopolitan distribution of free-living nematodes may rely on phoretic dispersal. We describe a new, inexpensive device to investigate individual phoretic events of the nematode Caenor...
Anna Siosiou,Erin E Sparks,Ioannis T Tsialtas
Anna Siosiou
Brace roots are common in large C 4 Poaceae species, such as maize and sorghum. However, in other species, these roots were either never reported, or the existence of the trait was neglected. Here we report the presence of brace roots in a ...
Chloe N Cordes,Melissa M Gouge,Hannah Morgan et al.
Chloe N Cordes et al.
An EMS-based forward genetic screen was conducted in an apoptotic null background to identify genetic aberrations that contribute to regulation of cell growth in Drosophila melanogaster . The current work maps the genomic location of one of...