A Competency Framework for Health Research Ethics Educational Programs: Results from a Stakeholder-Driven Mixed-Method Process [0.03%]
基于相关方的混合方法过程构建健康研究伦理教育项目胜任力框架的研究成果
Sean Tackett,Chirk Jenn Ng,Jeremy Sugarman et al.
Sean Tackett et al.
Educational programs are integral to building health research ethics (HRE) capacity, but no outcomes framework exists to guide them. We empirically developed a competency framework for health research ethics education-the Framework for Rese...
Offering Lottery Entry as an Incentive for Research Participation Compromises Informed Consent [0.03%]
作为研究参与激励的彩票抽奖方案会损害知情同意的有效性
Simon Paul Jenkins
Simon Paul Jenkins
This paper argues that offering entry into a lottery as an incentive to those who participate in research studies represents a challenge to the principle of informed, coercion-free consent that is considered an essential ingredient of permi...
Mark A Rothstein
Mark A Rothstein
Translational bioethics expands the scope of research ethics to include multidisciplinary analyses of the societal implications of new translational science discoveries. Novel health privacy issues are raised by the collection, use, and dis...
Remnant Blood Quantification: Informing the Definition of Minimal Risk in Clinical Research [0.03%]
余血量化：界定临床研究中的最小风险定义
Adam L Gottula,Sara Constand,Sandra Cabrera et al.
Adam L Gottula et al.
Guidelines from the Office for Human Research Protections regarding categories of research that institutional review boards (IRBs) may review through expedited procedures limit the volume of blood that can be obtained from research particip...
Jacob M Appel,Ilene Wilets
Jacob M Appel
The Covid-19 pandemic has raised a range of complex challenges for the research community in the United States. This essay uses Covid-19 as a model pandemic illness to consider two such issues that have yet to be fully explored in the ethic...
Legally Effective but Ethically Inadequate: Institutional Review Board Policies for Consent from Legally Authorized Representatives [0.03%]
合法但不道德：机构审查委员会代理人同意书政策的弊端
Robert R Harrison
Robert R Harrison
The prevailing approach to enrolling decisionally impaired adults in clinical research is to rely on permission from a default surrogate, one identified by law rather than by the prospective research participant. Reliance on a surrogate tra...
Disclosing Conflicts of Interest to Potential Research Participants: Good for Nothing? [0.03%]
告知受试者利益冲突：毫无作用吗？
Inmaculada de Melo-Martín
Inmaculada de Melo-Martín
The growing commercialization of science has raised concerns about financial conflicts of interest (COIs). Evidence suggests that such conflicts threaten the integrity of research and the well-being of research participants. Trying to minim...
Factors That Impact Hospital-Specific Enrollment Rates for a Neonatal Clinical Trial: An Analysis of the HEAL Study [0.03%]
影响新生儿临床试验入组率的因素：HEAL研究分析
Katherine F Guttmann,Sijia Li,Yvonne W Wu et al.
Katherine F Guttmann et al.
Inconsistent enrollment among hospitals for neonatal clinical trials may lead to study populations that are not representative of the patient population in the neonatal intensive care unit. The High-Dose Erythropoietin for Asphyxia and Ence...
Randomized Controlled Trial
Ethics & human research. 2023 Jan;45(1):29-38. DOI:10.1002/eahr.500154 2023
Public Policy Experiments without Equipoise: When Is Randomization Fair? [0.03%]
无均衡的公共政策实验：随机化何时才是公平的？
Douglas MacKay,Emma Cohn
Douglas MacKay
Government agencies and nonprofit organizations have increasingly turned to randomized controlled trials (RCTs) to evaluate public policy interventions. Random assignment is widely understood to be fair when there is equipoise; however, som...
Can the Research Team-Participant Relationship Ground Ancillary-Care Obligations? [0.03%]
研究团队与参与者的关系能否成为附属医疗责任的基础？
Henry S Richardson
Henry S Richardson
Discussion of medical researcher teams' ancillary-care obligations has long been dominated by partial-entrustment theory, developed in 2004 by the author of this article, in collaboration with Leah Belsky. Critics of the limited scope of th...