The Essential Need for Trust When Transmission Risk Cannot Be Eliminated in HIV-Remission Trials [0.03%]
当无法消除传播风险时艾滋缓解试验中所需的信任因素分析
Stuart Rennie,Gail Henderson,Nittaya Phanuphak et al.
Stuart Rennie et al.
Analytic treatment interruption (ATI) is scientifically necessary in HIV-remission ("cure") studies to test the effects of new interventions. However, stopping antiretroviral treatment poses risks to research participants and their sexual p...
John H Evans
John H Evans
Translational science is justified as advancing the public's interests but has no mechanism for determining these interests. Standard social science approaches would produce either unrepresentative descriptions or a cacophony of data not ea...
Antiracist Structural Intervention at the Emory University Institutional Review Board [0.03%]
埃默里大学机构审查委员会的反种族主义结构干预措施
Francois Rollin,Vanessa Van Doren,Jessica Alvarez et al.
Francois Rollin et al.
Although racial and ethnic categories are social constructs without inherent biologic or genetic meaning, race and ethnicity impact health outcomes through racism. The use of racial categories in biomedical research often misattributes the ...
Making an Advance Research Directive: An Interview Study with Adults Aged 55 and Older with Interests in Dementia Research [0.03%]
关于痴呆症研究有兴趣的55岁以上成年人制定预先医疗指示的研究访谈报告
Nola M Ries,Briony Johnston
Nola M Ries
Many people with dementia are interested in taking part in research, including when they no longer have capacity to provide informed consent. Advance research directives (ARD) enable people to document their wishes about research participat...
A Competency Framework for Health Research Ethics Educational Programs: Results from a Stakeholder-Driven Mixed-Method Process [0.03%]
基于相关方的混合方法过程构建健康研究伦理教育项目胜任力框架的研究成果
Sean Tackett,Chirk Jenn Ng,Jeremy Sugarman et al.
Sean Tackett et al.
Educational programs are integral to building health research ethics (HRE) capacity, but no outcomes framework exists to guide them. We empirically developed a competency framework for health research ethics education-the Framework for Rese...
Offering Lottery Entry as an Incentive for Research Participation Compromises Informed Consent [0.03%]
作为研究参与激励的彩票抽奖方案会损害知情同意的有效性
Simon Paul Jenkins
Simon Paul Jenkins
This paper argues that offering entry into a lottery as an incentive to those who participate in research studies represents a challenge to the principle of informed, coercion-free consent that is considered an essential ingredient of permi...
Mark A Rothstein
Mark A Rothstein
Translational bioethics expands the scope of research ethics to include multidisciplinary analyses of the societal implications of new translational science discoveries. Novel health privacy issues are raised by the collection, use, and dis...
Remnant Blood Quantification: Informing the Definition of Minimal Risk in Clinical Research [0.03%]
余血量化：界定临床研究中的最小风险定义
Adam L Gottula,Sara Constand,Sandra Cabrera et al.
Adam L Gottula et al.
Guidelines from the Office for Human Research Protections regarding categories of research that institutional review boards (IRBs) may review through expedited procedures limit the volume of blood that can be obtained from research particip...
Jacob M Appel,Ilene Wilets
Jacob M Appel
The Covid-19 pandemic has raised a range of complex challenges for the research community in the United States. This essay uses Covid-19 as a model pandemic illness to consider two such issues that have yet to be fully explored in the ethic...
Legally Effective but Ethically Inadequate: Institutional Review Board Policies for Consent from Legally Authorized Representatives [0.03%]
合法但不道德：机构审查委员会代理人同意书政策的弊端
Robert R Harrison
Robert R Harrison
The prevailing approach to enrolling decisionally impaired adults in clinical research is to rely on permission from a default surrogate, one identified by law rather than by the prospective research participant. Reliance on a surrogate tra...