Stakeholder Reflections on Implementing the National Institutes of Health's Policy on Single Institutional Review Boards [0.03%]
美国国立卫生研究院单一机构审查委员会政策的实施情况及各利益相关者观点
Amy Corneli,Kevin McKenna,Emily Hanlen-Rosado et al.
Amy Corneli et al.
The National Institutes of Health (NIH) requires use of a single institutional review board (sIRB) for multisite, nonexempt, NIH-funded research with human participants. The Clinical Trials Transformation Initiative (CTTI) conducted in-dept...
Gershom Chongwe,Joseph Ali,Dan Kabonge Kaye et al.
Gershom Chongwe et al.
Over recent decades, adaptive trial designs have been used more and more often for clinical trials, including randomized controlled trials (RCTs). This rise in the use of adaptive RCTs has been accompanied by debates about whether such tria...
Jon F Merz
Jon F Merz
Amy Karle
Amy Karle
Factors Associated with IRB Review Time in a Non-Federally Funded Study Using an sIRB of Record [0.03%]
非联邦资助研究中使用记录sIRB的因素与IRB审查时间的相关性分析
Erin Lamers-Johnson,Vanessa K Will,Julie M Long et al.
Erin Lamers-Johnson et al.
From 2018 to 2020, U.S. federal mandates began requiring the use of a single institutional review board (sIRB) of record for federally funded, multisite studies. With an interest in the efficiency of site activation, we compared the frequen...
Multicenter Study
Ethics & human research. 2023 Jul-Aug;45(4):16-29. DOI:10.1002/eahr.500173 2023
The Essential Need for Trust When Transmission Risk Cannot Be Eliminated in HIV-Remission Trials [0.03%]
当无法消除传播风险时艾滋缓解试验中所需的信任因素分析
Stuart Rennie,Gail Henderson,Nittaya Phanuphak et al.
Stuart Rennie et al.
Analytic treatment interruption (ATI) is scientifically necessary in HIV-remission ("cure") studies to test the effects of new interventions. However, stopping antiretroviral treatment poses risks to research participants and their sexual p...
John H Evans
John H Evans
Translational science is justified as advancing the public's interests but has no mechanism for determining these interests. Standard social science approaches would produce either unrepresentative descriptions or a cacophony of data not ea...
Antiracist Structural Intervention at the Emory University Institutional Review Board [0.03%]
埃默里大学机构审查委员会的反种族主义结构干预措施
Francois Rollin,Vanessa Van Doren,Jessica Alvarez et al.
Francois Rollin et al.
Although racial and ethnic categories are social constructs without inherent biologic or genetic meaning, race and ethnicity impact health outcomes through racism. The use of racial categories in biomedical research often misattributes the ...
Making an Advance Research Directive: An Interview Study with Adults Aged 55 and Older with Interests in Dementia Research [0.03%]
关于痴呆症研究有兴趣的55岁以上成年人制定预先医疗指示的研究访谈报告
Nola M Ries,Briony Johnston
Nola M Ries
Many people with dementia are interested in taking part in research, including when they no longer have capacity to provide informed consent. Advance research directives (ARD) enable people to document their wishes about research participat...