The Guatemalan Syphilis Trials, Community Engagement, and the Common Rule [0.03%]
危地马拉梅毒实验、社区参与和《共同规则》
Emma Z L Richardson,Mylini Saposan,Eric M Meslin et al.
Emma Z L Richardson et al.
The Role of Inclusion Benefits in Ethics Committee Assessment of Research Studies [0.03%]
伦理委员会评估研究中包容性惠益的作用
Stuart Rennie,Suzanne Day,Allison Mathews et al.
Stuart Rennie et al.
The relationship between risks and benefits is central to the ethics of research involving human participants. Traditionally, to be ethically justifiable, risks should be reasonable in relation to anticipated benefits (if any) to subjects a...
Jeri S Burr,Ann R Johnson,Valeriya Vasenina et al.
Jeri S Burr et al.
Implementing the National Institutes of Health's (NIH's) new single institutional review board (IRB) policy has caused a paradigm shift in IRB review across the country. IRBs and human research protection programs are looking more closely a...
Barbara E Bierer,Luke Gelinas
Barbara E Bierer
Susan E Lederer
Susan E Lederer
Strength through Structure: Defending a Structured Approach to Contraceptive Mandates in Clinical Research [0.03%]
避孕措施的结构化方法：临床研究中的防御策略
Toby L Schonfeld,Joseph S Brown,N Jean Amoura et al.
Toby L Schonfeld et al.
Burden or Opportunity? Parent Experiences When Approached for Research in a Pediatric Intensive Care Unit [0.03%]
负担还是机会？儿科重症监护室的研究招募家长经历探究
Erin Paquette,Avani Shukla,Jacob Davidson et al.
Erin Paquette et al.
Despite an ongoing need for pediatric research, low study enrollment may impede study completion, particularly in critical care. We conducted a prospective cross-sectional survey and chart review study to assess parent experiences with rese...
A Framework for Assessing Scientific Merit in Ethical Review of Clinical Research [0.03%]
临床研究伦理审查中评估科学价值的框架
Ariella Binik,Spencer Phillips Hey
Ariella Binik
Ethics guidelines and commentary suggest that a central function of research ethics committees is to assess the scientific merit of the protocols they review. However, some commentators object to this role, and evidence suggests that the as...
U.S. Public Health Service STD Experiments in Guatemala (1946-1948) and Their Aftermath [0.03%]
美国公共卫生部在危地马拉进行的性病实验（1946—1948）及其后续事件
Kayte Spector-Bagdady,Paul A Lombardo
Kayte Spector-Bagdady
The U.S. Public Health Service's sexually transmitted disease (STD) experiments in Guatemala are an important case study not only in human subjects research transgressions but also in the response to serious lapses in research ethics. This ...
Jane A Hartsock,Peter H Schwartz,Amy C Waltz et al.
Jane A Hartsock et al.
As pediatric biobank research grows, additional guidance will be needed about whether researchers should always obtain consent from participants when they reach the legal age of majority. Biobanks struggle with a range of practical and ethi...