Pregnant Women in Trials of Covid-19: A Critical Time to Consider Ethical Frameworks of Inclusion in Clinical Trials [0.03%]
新冠肺炎试验中的孕妇受试者:思考临床试验包容性伦理框架的关键时刻
Ruth Farrell,Marsha Michie,Rachel Pope
Ruth Farrell
Ethical issues abound during this unprecedented international public health crisis of Covid-19. While the trade-off between societal and individual interests that occurs at the intersection of public health ethics and clinical ethics affect...
Why Challenge Trials of SARS-CoV-2 Vaccines Could Be Ethical Despite Risk of Severe Adverse Events [0.03%]
为何新冠病毒疫苗挑战试验可能具有伦理性尽管存在发生严重不良事件的风险
Nir Eyal
Nir Eyal
Human challenge trials to test the efficacy of vaccine candidates against SARS-CoV-2, the novel coronavirus behind Covid-19, could save considerable time and many lives. But they may initially seem unethical because they expose healthy volu...
Deborah R Barnbaum
Deborah R Barnbaum
IRB Policies for Obtaining Informed Consent from Non-English-Speaking People [0.03%]
获取非英语人群知情同意的伦理审查委员会政策
Gianna McMillan
Gianna McMillan
United States regulations for the protection of human research subjects prescribe parameters for documentation of valid informed consent, which include the stipulation that the process be in a "language understandable to the subject." While...
Adolescent and Parent Perceptions about Participation in Biomedical Sexual Health Trials [0.03%]
青少年和家长对参与生物医学性健康试验的看法
Sara E Landers,Jenny K R Francis,Marilyn C Morris et al.
Sara E Landers et al.
Given the burden of HIV and other sexually transmitted infections among adolescents who are legal minors, it is critical that they be included in biomedical sexual health trials to ensure that new prevention and treatment interventions are ...
Genomics and Infectious Diseases: Expert Perspectives on Public Health Considerations regarding Actionability and Privacy [0.03%]
基因组学和传染病:关于行动性和隐私性的公共卫生行动及专家视角
Alexis Walker,Angie Boyce,Priya Duggal et al.
Alexis Walker et al.
There is growing evidence that human genetics plays a significant role in shaping human responses to infectious diseases. For instance, individuals' genetic susceptibility or resistance to infectious disease is likely to affect disease tran...
The Importance of Engaging Children in Research Decision-Making: A Preliminary Mixed-Methods Study [0.03%]
一项初步混合研究法研究:儿童参与决策的重要性
Erin Talati Paquette,Hannah Palac,Elizabeth Bair et al.
Erin Talati Paquette et al.
Studies demonstrate deficiencies in parents' and children's comprehension of research and lack of child engagement in research decision-making. We conducted a cross-sectional and interview-based study of 31 parent-child dyads to describe de...
Nancy M P King
Nancy M P King
Equitably Sharing the Benefits and Burdens of Research: Covid-19 Raises the Stakes [0.03%]
公平地分享研究的成果与负担:新冠疫情加大了挑战
Carl H Coleman
Carl H Coleman
Jessica Mozersky,Meredith Parsons,Heidi Walsh et al.
Jessica Mozersky et al.
We found no studies in the United States that explored research participants' perspectives about sharing their qualitative data. We present findings from interviews with 30 individuals who participated in sensitive qualitative studies to ex...