Benefit Sharing for Human Genomics Research: Awareness and Expectations of Genomics Researchers in Sub-Saharan Africa [0.03%]
撒哈拉以南非洲基因组学研究人员的利益共享意识及其期望：基因组研究利益分享机制探究
Nchangwi Syntia Munung,Jantina de Vries
Nchangwi Syntia Munung
Benefit sharing is an ethical issue that underscores the need to find a balance between access to genetic resources and the provision of fair benefits in exchange for access. The Human Genome Organisation (HUGO) is one of the few initiative...
Ethical and Practical Concerns about IRB Restrictions on the Use of Research Data [0.03%]
伦理学和实践中的IRB对研究数据使用限制的担忧
Mark Barnes,Judith Carrithers,Jeremy Sugarman
Mark Barnes
In response to researcher noncompliance with ethical and regulatory provisions governing research with humans, protocol deviations, and unanticipated problems with research, institutional review boards (IRBs) or institutions sometimes impos...
Thought Leader Comparisons of Risks in Precision Medicine Research [0.03%]
精准医学研究中的风险比较及相关性——思想领导者的观点
Laura M Beskow,Catherine M Hammack-Aviran,Kathleen M Brelsford
Laura M Beskow
Biomedical research is increasingly capitalizing on an array of data to illuminate the interplay between "omics," lifestyle, and health. Leveraging this information presents opportunities to advance knowledge but also poses risks to researc...
Big Data, Biomedical Research, and Ethics Review: New Challenges for IRBs [0.03%]
大数据、生物医学研究及伦理审查：IRB面临的新的挑战
Agata Ferretti,Marcello Ienca,Samia Hurst et al.
Agata Ferretti et al.
The increased use of big data in the medical field has shifted the way in which biomedical research is designed and carried out. The novelty of techniques and methods brought by big data research brings new challenges to institutional revie...
Ethical and Regulatory Concerns in Pragmatic Clinical Trial Monitoring and Oversight [0.03%]
务实临床试验监控和监管中的伦理及法规关注点
Michelle K Roberts,Dylan M Fisher,Lea E Parker et al.
Michelle K Roberts et al.
The implementation of pragmatic clinical trials (PCTs) can be accompanied by unique regulatory challenges. In this paper, we describe the experience and management of regulatory noncompliance during a 25-site acute care PCT. During the tria...
Published Erratum
Ethics & human research. 2020 Sep;42(5):16. DOI:10.1002/eahr.500063 2020
Person-Oriented Research Ethics to Address the Needs of Participants on the Autism Spectrum [0.03%]
面向参与者的伦理研究以满足自闭症谱系参与者的需求
M Ariel Cascio,Jonathan A Weiss,Eric Racine
M Ariel Cascio
Research ethics scholarship often attends to vulnerability. People with autism may be vulnerable in research, but are also vulnerable to unjust exclusion from participation. Addressing the needs of participants with autism can facilitate in...
Published Erratum
Ethics & human research. 2020 Jul;42(4):16. DOI:10.1002/eahr.500057 2020
The Pathway Forward: Insights on Factors that Facilitate Research with Pregnant Women [0.03%]
展望未来：关于促进孕产妇研究因素的见解
Anna C Mastroianni,Robert Franceschini,Sarah L Wicks et al.
Anna C Mastroianni et al.
The near-routine exclusion of pregnant women from clinical research has resulted in evidence gaps that endanger the health of pregnant women and their future offspring. Although existing literature documents numerous obstacles along the cli...
Advantages of Using Lotteries to Select Participants for High-Demand Covid-19 Treatment Trials [0.03%]
关于高需求新冠治疗试验受试者选拔的彩票制度的优点
Alexander A Iyer,Saskia Hendriks,Annette Rid
Alexander A Iyer
As hospitals have experienced a surge of Covid-19 patients, investigators of Covid-19 treatment trials face a difficult problem: when an institution has more eligible and interested patients than trial slots, who should be enrolled? Definin...