The Ethics of Repurposing Previously Collected Research Biospecimens in an Infectious Disease Pandemic [0.03%]
传染病大流行期间重新利用先前采集的研究生物样本的伦理问题
Benjamin E Berkman,Anna C Mastroianni,Leila Jamal et al.
Benjamin E Berkman et al.
In the early days of a pandemic, repurposing biospecimens from established research projects could prove to be extraordinarily useful in achieving substantial and timely public health benefits. Nonetheless, there are potential ethical and r...
Holly Fernandez Lynch,Dawn Lundin,Emma A Meagher
Holly Fernandez Lynch
Employees are often considered a vulnerable research population due to concerns about consent and confidentiality, but there is insufficient guidance regarding their ethical inclusion in research. In the context of Covid-19, frontline healt...
Should Participants in Clinical Trials Be Able to Withdraw from Passive Follow-Up? [0.03%]
临床试验受试者能否退出被动随访？
Warren H Capell,Matthew K Wynia,Elisa A Hurley et al.
Warren H Capell et al.
A research participant's right to withdraw from all research procedures is widely accepted, but there can be justifiable limits to a participant's exercise of autonomy to withdraw from some procedures. Clinical outcomes trials depend on com...
Should the Regulation of Research Misconduct Be Integrated with the Ethics Framework Promulgated in The Belmont Report? [0.03%]
应当将科研不当行为的规范纳入贝尔蒙报告中的伦理框架吗？
Barbara K Redman,Arthur L Caplan
Barbara K Redman
The federal research misconduct regulations finalized in 2005 did not incorporate important principles regarding human subjects protections articulated in The Belmont Report, yet research misconduct can involve harms to research subjects an...
Christopher Robertson
Christopher Robertson
In prospective interventional research, a treatment may provide an advantage for the recipient over other people who do not receive it. If the intervention proves successful, the treated are better able to compete for such things as a scarc...
What Factors Predict Willingness to Join Low-Risk Pragmatic Clinical Trials? [0.03%]
什么因素预测参与低风险实用临床试验的意愿？
Stephanie R Morain,Nancy E Kass,Ruth R Faden
Stephanie R Morain
Pragmatic clinical trials (PCTs) may improve the efficiency, relevance, and representativeness of research. While prior research has indicated that willingness to join a PCT is high, it is not universal among those asked in surveys explorin...
Connie M Ulrich,Christine Grady,George Demiris et al.
Connie M Ulrich et al.
Privacy and confidentiality of personal medical information are cornerstones of ethical clinical care and ethical research. But real-world research has challenged traditional ways of thinking about privacy and confidentiality of information...
Case Reports
Ethics & human research. 2021 Jan;43(1):25-31. DOI:10.1002/eahr.500076 2021
Published Erratum
Ethics & human research. 2020 Nov;42(6):20. DOI:10.1002/eahr.500070 2020
Ethical Considerations When Using a Mobile Eye Tracker in a Patient-Facing Area: Lessons from an Intensive Care Unit Observational Protocol [0.03%]
在患者区域使用移动眼动仪时的伦理考量——来自重症监护病房观察计划的经验教训
Ethan P Larsen,Jacob M Kolman,Faisal N Masud et al.
Ethan P Larsen et al.
This article describes the process of designing, approving, and conducting an investigator-initiated protocol to use an eye-tracking device in a health care setting. Participants wore the device, which resembles eyeglasses, in a front-facin...
Observational Study
Ethics & human research. 2020 Nov;42(6):2-13. DOI:10.1002/eahr.500068 2020
Loopholes in the Research Ethics System? Informed Consent Waivers in Cluster Randomized Trials with Individual-Level Intervention [0.03%]
群随机试验中免除知情同意书的现象及伦理审校系统中的漏洞？以个体层面干预为例
Alex John London,Monica Taljaard,Charles Weijer
Alex John London
Individual-cluster trials randomize groups of individuals but deliver study interventions directly to individual participants. We examine three arguments that might justify the perception that the bar for a waiver of consent should be lower...