The Ethical Implications of Big Data Research in Public Health: "Big Data Ethics by Design" in the UK-REACH Study [0.03%]
英国公共卫生大数据研究的伦理影响——UK-REACH研究中的“设计伦理学”
Ruby Reed-Berendt,Edward S Dove,Manish Pareek;UK-REACH Study Collaborative Group
Ruby Reed-Berendt
In this article, we analyze legal and ethical issues raised in Big Data health research projects in the Covid-19 era and consider how these issues might be addressed in ways that advance positive values (e.g., furtherance of respect for per...
Published Erratum
Ethics & human research. 2022 Jan;44(1):17. DOI:10.1002/eahr.500113 2022
How Scientists Perceive CRISPR's Translational Promise and the Implications for Individuals with Genetic Conditions [0.03%]
科学家如何看待CRISPR的转化应用前景及其对遗传疾病患者的影响
Jodi Halpern,Sharon E O&#x;Hara,Aleksa L Owen et al.
Jodi Halpern et al.
CRISPR (clustered regularly interspaced short palindromic repeats) somatic genome editing, an important promissory technology, presents a case study of the movement of basic scientists into translational research. In this paper, we explore ...
An Approach to Reviewing Local Context for Exception from Informed Consent Trials Using a Single IRB [0.03%]
使用单一机构审查委员会对知情同意例外试验的局部环境进行审查的方法
Ann R Johnson,Lisa M Rigtrup,John VanBuren et al.
Ann R Johnson et al.
In the context of emergency research, researchers can ask the institutional review board (IRB) to waive the regulatory requirement that individuals provide informed consent when enrolling in research studies. A requirement of the waiver of ...
Physician Perspectives on Including Pregnant Women in Covid-19 Clinical Trials: Time for a Paradigm Change [0.03%]
医生对将孕妇纳入COVID-19临床试验的态度：是时候改变理念了
Marie-Julie Trahan,Annabelle Cumyn,Matthew P Cheng et al.
Marie-Julie Trahan et al.
Excluding pregnant people from Covid-19 clinical trials may lead to unintended harmful consequences. For this study, an online questionnaire was sent to physicians belonging to Canadian professional medical associations in order to evaluate...
Steps toward a System of IRB Precedent: Piloting Approaches to Summarizing IRB Decisions for Future Use [0.03%]
迈向IRB先例体系的步骤：试点总结IRB决策的方法以供将来使用
Andrea Seykora,Carl Coleman,Stephen J Rosenfeld et al.
Andrea Seykora et al.
Institutional review boards (IRBs) have been criticized for inconsistency and lack of transparency in decision-making, problems that undermine both trust in their ability to protect human research participants and respect for their decision...
A Call for Better, Not Faster, Research Ethics Committee Reviews in the Covid-19 Era [0.03%]
新冠疫情时期的伦理审查：质量而非速度
Leonardo Tamariz,Fred J Hendler,John M Wells et al.
Leonardo Tamariz et al.
With the rapid spread of SARS-CoV2 has come a rapid proliferation of clinical research studies, resulting in considerable strain on research ethics committees (RECS), which need to review study proposals. RECs are pressured to move through ...
Opt-Out Design for an Observational Toxicology Study Involving Intoxicated Patients at a Dance Music Event [0.03%]
音乐节醉酒患者参与的观察性毒理学研究退出设计
Paul Calle,Peter Blanckaert,Sabine Lemoyne et al.
Paul Calle et al.
At electronic dance music events in Belgium in 2013 to 2015, seemingly intoxicated patients were included without their informed consent in an observational toxicology study when the attending physicians determined that they needed treatmen...
IRB Decision-Making about Minimal Risk Research with Pregnant Participants [0.03%]
涉及孕妇受试者的最小风险研究的伦理审查决策问题
Amina White,Christine Grady,Margaret Little et al.
Amina White et al.
Pregnant individuals are often excluded from research without clear justification, even when the research poses minimal risk of harm to the fetus. Little is known about institutional review board (IRB) decision-making practices when reviewi...
Making Metrics Meaningful: How Human Research Protection Programs Can Efficiently and Effectively Use Their Data [0.03%]
质量指标：如何高效利用数据保护人类研究项目
Kimberley Serpico
Kimberley Serpico
Human research protection programs (HRPP) generate an abundance of data on performance, capacity, and compliance. When used effectively, this information can be instrumental in helping HRPPs meet programmatic and institutional goals, demons...