Lisa E Smilan
Lisa E Smilan
Biobanks and health data repositories provide rich reservoirs of information for use in biomedical research. These repositories depend on participants donating identifiable health data and biospecimens that may be used in perpetuity by unli...
Informed Consent for Placebo-Controlled Trials: Do Ethics and Science Conflict? [0.03%]
安慰剂对照试验中的知情同意：伦理与科学冲突吗？
Hope A Feldman,James A Feldman,Charles C Miller et al.
Hope A Feldman et al.
The use of a placebo has been considered the best method for controlling bias in a prospective randomized clinical trial and provides the most rigorous test of treatment efficacy for evaluating a medical therapy. Placebos commonly produce c...
Randomized Controlled Trial
Ethics & human research. 2022 Sep;44(5):42-48. DOI:10.1002/eahr.500142 2022
Laura A Levit,Julie Kaneshiro,Jeffrey Peppercorn et al.
Laura A Levit et al.
Research biopsies included in cancer clinical trials have the goal of advancing scientific understanding of the biological bases of cancer and its treatments, but may offer no prospect of direct benefit to participants and often pose more t...
Published Erratum
Ethics & human research. 2022 Sep;44(5):21. DOI:10.1002/eahr.500138 2022
Ethical Considerations during the Informed Consent Process for Acute Ischemic Stroke in International Clinical Trials [0.03%]
国际卒中临床试验中知情同意的伦理问题
Tiffany Bellomo,Jennifer Fokas,Noah Tsao et al.
Tiffany Bellomo et al.
We sought to investigate the experiences of researchers in existing active-control trials in acute ischemic stroke comparing investigational therapy to tissue plasminogen activator (tPA) in order to identify the approaches and challenges in...
Privacy Risks in Microbiome Research: Public Perspectives before and during a Global Pandemic [0.03%]
宏基因组研究中的隐私风险：全球大流行病前后的公众看法
Andrea Shin,Huiping Xu
Andrea Shin
We assessed public perspectives of microbiome research privacy risks before and after a nationwide emergency was declared in the United States regarding the Covid-19 pandemic. From January to July of 2020, we conducted an online survey of p...
Developing and Implementing Electronic Consent Procedures in Response to Covid-19 Restrictions [0.03%]
新冠肺炎疫情期间电子版知情同意书的制定与实施
Julie R Bromberg,Evelyn Nimaja,Andrew W Kiragu et al.
Julie R Bromberg et al.
The Covid-19 pandemic resulted in unprecedented restrictions on many public, private, and workplace activities throughout the United States and elsewhere. When restrictions were imposed, we were conducting a type III hybrid effectiveness-im...
Perspectives from a Predominantly African American Community about Biobank Research and a Biobank Consent Form [0.03%]
一个以非裔美国人为主的社区对生物银行研究及知情同意书的观点
Laura K Sedig,E Hill De Loney,Sarah B Bailey et al.
Laura K Sedig et al.
Minority populations have been underrepresented in clinical trials, as well as in research biobanks that are created to conduct research with participants' biospecimens and related medical and research data. Biobank research raises issues a...
Megan Doerr,Sara Meeder
Megan Doerr
Much of precision medicine is driven by big health data research-the analysis of massive datasets representing the complex web of genetic, behavioral, environmental, and other factors that impact human well-being. There are some who point t...
Marion Danis
Marion Danis
Published Erratum
Ethics & human research. 2022 Jul;44(4):33. DOI:10.1002/eahr.500131 2022