Victoria Higgins,Mikayla Steinbach,Fahed Elian et al.
Victoria Higgins et al.
Background: Early detection of monoclonal gammopathies is challenging, as they often remain undiagnosed until morbidity develops. Monoclonal proteins (M-proteins), particularly IgM, can interfere with the lipemia index (L...
Using ddPCR to Identify Large Deletions of Complement Factor H-Related Genes in Atypical Hemolytic Uremic Syndrome [0.03%]
应用ddPCR技术鉴别解体型溶血性尿毒综合征患者补体因子H相关基因的大片段缺失变异
Yu-Wei Cheng,Zhen Wang,Zheng Jin Tu et al.
Yu-Wei Cheng et al.
Background: Atypical hemolytic uremic syndrome (aHUS) is a rare, complement-mediated disorder. Disease-associated variants have been found in complement factor H-related genes and complement regulatory genes. Particularly...
Analytical and Clinical Validity of a High-Throughput, Fully Automated Immunoassay for Plasma Neurofilament Light Chain [0.03%]
高通量全自动免疫测定法检测血浆神经丝轻链的分析及临床有效性
Dusten Unruh,Jeff Todtleben,Kara Johnson et al.
Dusten Unruh et al.
Background: Neurofilament light chain (NfL) has emerged as a promising blood-based biomarker for neuroaxonal damage across neurological disorders. Clinical utility has been correlated with disease activity, treatment resp...
Development of a Low-Cost Spectrometer for Hemolysis Detection in Emergency Blood Gas Samples [0.03%]
低成本血气样本溶血检测光谱仪的开发研究
Qian Dai,Jia-Yin Tu,Kou-Qiong Wang et al.
Qian Dai et al.
Background: Hemolysis is a major cause of sample rejection in blood gas analysis. We aimed to develop a low-cost spectrometer for hemolysis detection in emergency laboratories. ...
Clinical Implications of the Duffy-Null Genotype in Patients on Azathioprine or Methotrexate in the All of Us Cohort [0.03%]
Duffy-Null基因型在美国全民队列中使用硫唑嘌呤或甲氨蝶呤的患者中的临床意义
Edgar Asiimwe,Donglei Hu,Jing Cheng et al.
Edgar Asiimwe et al.
Background: The Duffy null variant (CC genotype) is associated with lower absolute neutrophil count (ANC) and increased risk of early discontinuation or ineligibility for certain treatments. Our primary objective was to e...
Improved Precision of Point-of-Care Analyzers with Automation of Sample Processing [0.03%]
自动化样本处理提高POCT检测精密度研究
Alan H B Wu,Chui Mei Ong,Melissa Alamillo et al.
Alan H B Wu et al.
Huini Zheng,Li Zou,Junge Zhang
Huini Zheng
Evaluation of a Publicly Available Artificial Intelligence Model for Interpretation of Stains and Smears for Infectious Diseases Diagnosis [0.03%]
评估一种用于感染性疾病诊断的公开人工智能模型在染色和涂片解释方面的性能
Siham Hattab,Stevephen Hung,Deneen Nault et al.
Siham Hattab et al.
Total Serum Calcium Spike-Recovery Experiments to Investigate Bones of Contention in Clinical Laboratories [0.03%]
临床实验室中骨骼争议的总血清钙尖峰恢复实验调查研究
Sarah L Davies,Rachel Marrington,Iryna Mikheenko et al.
Sarah L Davies et al.
Background: To help assess patient safety risks associated with ongoing differences in total calcium assays following bias shifts, we performed spike-recovery experiments within our clinical chemistry external quality ass...