Current State and Needs of Clinical Laboratories in Selected Countries in Africa [0.03%]
撒哈拉以南非洲国家的临床实验室现状及需求调查
Merih Tesfazghi,Anne E Tebo,Roa Harb et al.
Merih Tesfazghi et al.
The Africa Working Group, under the auspices of the Global Laboratory Quality Initiative of the Association for Diagnostics & Laboratory Medicine (ADLM), conducted several educational workshops in Africa to promote laboratory quality in the...
A Dynamic, Continuous Model for Age-Specific Anemia Classification in Children and Non-Pregnant Women [0.03%]
儿童和非孕妇动态连续年龄特异性贫血分类模型
Charles P Wakim,Carla A El-Mallah,James P Wirth et al.
Charles P Wakim et al.
Background: Fixed hemoglobin cutoffs are commonly used to define anemia, yet hemoglobin concentration varies physiologically with age. Rigid thresholds may therefore misclassify individuals, particularly in early childhoo...
A Large-Scale Study Identifies a TgAb Interference Threshold for Thyroglobulin Immunoassays Using Segmented Regression and Bootstrap Validation [0.03%]
基于分段回归和自助法验证的Tg抗体干扰阈值的研究
Qianhui Liu,Lan You,Heye Lv et al.
Qianhui Liu et al.
Background: Thyroglobulin (Tg) measurement is key for differentiated thyroid cancer (DTC) follow-up, but anti-Tg antibodies (TgAbs) can interfere with Tg immunoassays and bias Tg interpretation. Current TgAb cutoffs are h...
Sustainability through Evidence-Based Equations: A Pilot Study Modeling the Friedewald and NIH-Sampson Equations [0.03%]
基于证据的公式化可持续性研究：弗里德瓦尔德和NIH-桑普森公式的建模试点研究
Stephanie A Hart,Joesph R Wiencek
Stephanie A Hart
Assessment of TIMP1, Transgelin-2, and Procalcitonin as Protein Biomarkers for Diagnosis and Prognosis of Bloodstream Infection in a Critically Ill Cohort [0.03%]
TIMP1、transgelin-2和procalcitonin作为诊断和预测危重患者血流感染的蛋白质生物标志物的价值评估
Sajal Tiwary,Caroline A O&#x;Neil,Sydney Lawless et al.
Sajal Tiwary et al.
Background: Bloodstream infections (BSI) are a significant contributor to morbidity and mortality among hospitalized patients. Rapid diagnosis of BSI is critical for timely and appropriate clinical management, but current...
Sixth Generation High-Sensitivity Cardiac Troponin T: Will a Better Assay Make a Better Biomarker? [0.03%]
第六代高敏心肌肌钙蛋白T检测：更好的检测能否造就更佳的标志物？
Amber Pollock,Alexander J F Thurston,Andrew R Chapman et al.
Amber Pollock et al.
AI'm Here to Help: Enhancing Laboratory Genetic Counseling with Artificial Intelligence [0.03%]
“AI助您：用人工智能增强实验室遗传咨询”
Zöe Powis,Khalida Liaquat,Matthew L Tschirgi
Zöe Powis
Background: Artificial intelligence (AI) is transforming the fields of genetics and genetic counseling, enhancing both clinical and laboratory practices. The rise of AI technologies has drawn attention to their potential ...
Analytical Performance of the Sixth Generation High-Sensitivity Cardiac Troponin T Assay [0.03%]
第六代高敏肌钙蛋白T检测的性能评估分析
Mengyuan Ge,Lori B Daniels,Spencer Seely et al.
Mengyuan Ge et al.
Background: High-sensitivity cardiac troponin assays are integral to diagnosing myocardial infarction. The current Roche Elecsys® Troponin T high-sensitivity Gen 5 assay (Gen 5) received FDA clearance in 2017. A sixth-ge...
Result Interpretation in Skewed Populations-Are Common Reference Intervals Inadequate? [0.03%]
偏斜人群的结果解读-常见的参考区间是否不够用？
Dennis J Orton,Jessica L Gifford,Gregory A Kline
Dennis J Orton
Background: Reference intervals (RIs) are defined as the central 95th percentile of a healthy population, and many biomarkers exhibit a skewed result distribution. Here we demonstrate interpretive variations for results f...