Metal-Phenolic Coordination mediated Nanoemulsions for All-in-One Drug Delivery [0.03%]
金属-酚类配位介导的纳米乳液用于药物一体输送体系
Yeji Jeon,Jun Woo Park,Su Jin Lee et al.
Yeji Jeon et al.
Combination chemotherapy is a promising strategy for cancer treatment, enhancing antitumor efficacy while minimizing drug resistance and mitigating the risk of single-drug overdose toxicity. Polymeric drug delivery carriers for combination ...
Regulation of Brain Metastatic Breast Cancer Cell Dormancy versus Proliferation on Hyaluronic Acid Hydrogels via Laminin and Laminin-Derived Peptides [0.03%]
通过层粘连蛋白和层粘连蛋白衍生的肽在透明质酸水凝胶上调节脑转移性乳腺癌细胞休眠与增殖
Kasra Goodarzi,Paromita Sarker,Shreyas S Rao
Kasra Goodarzi
Among the secondary target organs for metastatic breast cancer, brain metastasis is extremely aggressive in nature, resulting in lower survival rates. These metastatic cancer cells have the potential to enter a dormant state in the brain, a...
RmZHD Surface-Displayed Escherichia coli for High Efficiency and Low-Cost Degradation of Zearalenone [0.03%]
高效的低成本降解玉米赤霉烯酮的RmZHD表面展示大肠杆菌
Haoxiang Chen,Xiaoyu Wang,Hui Ge et al.
Haoxiang Chen et al.
Zearalenone (ZEN) is one of the most prevalent mycotoxins in the world, with estrogenic toxicity leading to significant annual economic losses and environmental pollution. RmZHD, a novel ZEN hydrolase, surpasses the efficiency of its predec...
Aggregation-Induced Photosensitization of Long-Chain-Substituted Osmium Complexes for Lysosomes Targeting Photodynamic Therapy [0.03%]
长链取代的锇配合物聚集诱导光敏化作用在溶酶体靶向光动力疗法中的应用
Ziyu Zhou,Shuo Li,Xiuqian Ding et al.
Ziyu Zhou et al.
Photodynamic therapy (PDT) has been demonstrated to be an effective tool for cancer treatment. Seeking organelle-targeting photosensitizers (PSs) with robust reactive oxygen species (ROS) production is extremely in demand. Herein, we propos...
Poly(vinyl alcohol)/Polycaprolactone Nanofiber Enriched with Lichenysin against Multidrug-Resistance Bacterial Infection in Wound Healing: In Vitro Studies and In Vivo Evaluation in Wistar Rats [0.03%]
富含苔苯素的聚乙烯醇/己内酯纳米纤维在伤口愈合中对抗多药耐药细菌感染：体外研究和体内评价在大鼠中的应用
Swati Yadav,Dilip Kumar Arya,Shubham Kanaujiya et al.
Swati Yadav et al.
Multidrug resistance (MDR) infectious wounds are a major concern due to drug resistance, leading to increased patient morbidity. Lichenysin (LCN), a lipopeptide and biosurfactant obtained from certain strains of Bacillus licheniformis, has ...
Fabrication of Folic Acid-Derived Carbon Dot-Conjugated Chitosan Nanospheres as Theragnostic Agents for pH-Responsive Anticancer Drug Delivery [0.03%]
叶酸衍生碳点介导的纳米壳结构的构建作为智能诊疗体系用于肿瘤的靶向治疗及检测
Trisita Ghosh,Madhurima Mandal,Moumita Shee et al.
Trisita Ghosh et al.
The favorable success rate in cancer treatment predominantly depends on precise diagnosis with target-specific drug delivery, which can regulate the patient survival outcome rate. Moreover, proper tracking of the system's pH is very much cr...
Robust Acid-Responsive AILE Luminescence Effect Nanoparticle for Drug Release Monitoring and Induction of Apoptosis in Cancer Cells [0.03%]
robust acid-responsive AILE luminescence effect nanoparticle 用于药物释放监测及诱导癌细胞凋亡中的应用研究
Chang Cao,Wen Wang,Shuo Zhu et al.
Chang Cao et al.
Through the PFOEP-SO3(-) + multidrug molecules constructed nanoparticle (NP) experiments and validated by molecular simulation docking experiments, we propose a molecular interaction principle for inducing aggregation-induced locally excite...
Advanced Exosome Isolation through Electrophoretic Oscillation-Assisted Tangent-Flow Ultrafiltration with a PVDF-Fiber-Coated SiNx Nanofilter [0.03%]
基于PVDF纤维涂层的SiNx纳米过滤器电泳振荡切向流超滤技术高效分离外泌体
Hansol Lee,Jaehyuk Lee,Minji Ko et al.
Hansol Lee et al.
This study introduces a comprehensive approach to enhancing SiNx nanofilters for exosome isolation from bovine milk using the electrophoretic oscillation-assisted tangent-flow ultrafiltration (EPOTF) process. Reinforcing the nanofilter with...
Copper and Nitrogen Codoped CDs for Alleviating the Damage of Reactive Oxygen Species for Cucumber Seedlings under Salt Stress [0.03%]
铜/氮共掺杂的CDs通过缓解盐胁迫下黄瓜幼苗的活性氧损伤来提高其耐盐性
Chen Li,Jieqiang Tan,Zhiwei Zhang et al.
Chen Li et al.
Dramatic changes in climate and soil environments have made growing conditions for crops more challenging. These crops are subject to a range of abiotic stresses in different environments, which can lead to significant yield losses, resulti...
Enhanced In Vitro and In Vivo Autophagy Suppression via LC3 siRNA-Loaded "Smart" Nanoparticles and Doxorubicin Combination Therapy in Triple Negative Breast Cancer [0.03%]
通过LC3 siRNA负载的"智能"纳米粒子和多西他赛联合治疗增强三阴性乳腺癌的体外和体内自噬抑制作用
Nada Walweel,Venhar Cinar,Osman Mersin et al.
Nada Walweel et al.
Autophagy plays a complex role in cancer progression, serving as both a tumor suppressor and a promoter, depending on the context. In triple-negative breast cancer (TNBC), a particularly aggressive subtype with limited therapeutic options, ...