Modulating Cytotoxicity in HeLa Cells via Aromatic Ring Variation in Cu(I) Complexes [0.03%]
通过调控Cu(I)配合物的芳环结构来调节其在HeLa细胞中的毒性大小
Riya Kumari,Swati Singh,Shivendra Kumar Pandey et al.
Riya Kumari et al.
The persistent global burden of cancer underscores the need for alternative therapeutic strategies beyond conventional chemotherapeutics, with metal-based agents offering distinct advantages due to their structural tunability and diverse bi...
Curcumin-Integrated Smart Nanocarriers: A Multi-Stimuli-Responsive Platform for Targeted Delivery of 5-Fluorouracil in Cancer Therapy [0.03%]
具有姜黄素的智能纳米载体：癌症治疗中用于递送5-氟尿嘧啶的多刺激响应型靶向平台
Twara Kikani,Aarti Odedara,Sonal Thakore
Twara Kikani
Conventional chemotherapy for cancer treatment often suffers from limitations such as non-specificity, multidrug resistance (MDR), poor drug circulation, and rapid metabolism. Designing a nanocarrier system with a targeting ability may aid ...
Host-Guest Interaction-Instructed In Situ Self-Assembly of Therapeutic Peptides for Enhancing Antitumor Efficacy [0.03%]
主客体相互作用指导的治疗肽原位自组装用于增强抗肿瘤功效
Minghui Yu,Wujuan Zhu,Taoli Sun et al.
Minghui Yu et al.
Therapeutic peptides have played a huge role in chemotherapy due to their excellent biological activity and biocompatibility. However, therapeutic peptides are vulnerable to enzymatic digestion, which makes them with fast elimination in viv...
Bioinspired Engineering of Bombyx mori Silk Fibroin: Solution Blow-Spun Nanofibers Hybridized with (3-Aminopropyl)triethoxysilane [0.03%]
受生物启发的家蚕丝素纳米纤维素与（3-氨丙基）三乙氧基硅烷的工程学研究：溶液喷射纺纳米纤维
Amanda R Sorigotti,Rafaella T Paschoalin,Robson Rosa da Silva et al.
Amanda R Sorigotti et al.
The development of bioinspired nanofibrous scaffolds with adjustable functions is essential for a range of applications, from tissue engineering to sustainable materials that exploit the hierarchical architectures of Bombyx mori silks. In t...
Core-Shell Electrospun Membranes Enable Antimicrobial and Immunomodulatory Local Therapy for Periodontitis [0.03%]
核壳静电纺丝膜可同时实现抗菌和免疫调节局部治疗以修复牙周组织损伤
Angeliki Koimtzidou,Konstantina Chachlioutaki,Foteini Machla et al.
Angeliki Koimtzidou et al.
Periodontitis is a chronic inflammatory disease that progressively destroys periodontal tissues and can lead to tooth loss, affecting more than one billion people worldwide. Here, we developed coaxial electrospun core-shell scaffolds design...
Covalent Immobilization of Hydrogels on Carbon Fiber Microelectrodes for the Determination of Dopamine in the Living Mouse Brain [0.03%]
用于活体小鼠脑内多巴胺检测的碳纤维微电极上固定水凝胶的研究
Jiatao Chen,Fuyun Xia,Xinxin Zhao et al.
Jiatao Chen et al.
Real-time and in situ monitoring of dynamic changes in brain neurotransmitters is of significant importance for understanding their pathophysiological regulatory mechanisms. This study employed an in situ hydrogel covalent immobilization st...
Gold Nanoparticles Combine with Radiation Therapy to Drive Immunogenic Macrophage Reprogramming [0.03%]
金纳米颗粒与放射疗法结合驱动免疫性巨噬细胞重编程
Shalini Iyer,Tijani Tabarrant,Benjamin Ledoux et al.
Shalini Iyer et al.
Heavy-metal-based nano-objects have been recently shown to act as radiosensitizers. One possible underlying mechanism causing this effect is the amplification of reactive oxygen species (ROS) production upon irradiation. This reaction could...
Multifunctional Hemostatic Hydrogels Based on Natural Ionic Polymers: Dual Crosslinking Strategy for Rapid Bleeding Control and Infected Wound Management [0.03%]
基于天然离子聚合物的多功能止血水凝胶：快速止血和感染伤口管理的双交联策略
Runxuan Liu,Sadaqat Ali Chattha,Qingshuang Song et al.
Runxuan Liu et al.
Uncontrolled hemorrhage remains a critical challenge in emergency and trauma scenarios, with limited options that combine rapid hemostasis, robust wet-tissue adhesion, and infection prevention in a single platform. Herein, this study report...
Bifunctional Composite Biomaterials Integrating Bacteriophages and Phytoextracts for Chronic Wound Healing [0.03%]
集细菌噬菌体和植物提取物于一体的双功能复合生物材料促进慢性伤口愈合
Rutwik Gawas,Nidhi Sapre,Santosh Koratkar et al.
Rutwik Gawas et al.
Chronic wounds are complex and dynamic environments that pose challenges due to impaired healing and bacterial infections, which are increasingly difficult to address because of antimicrobial resistance. Therefore, the infected and damaged ...
Design and Evaluation of Gellan/Boron-dipyrromethene as a Photoactive Hydrogel and Efficiency as Antiyeast Activity [0.03%]
海藻酸/硼二吡咯甲烷的 design 和评价及抗酵母活性效率研究
Shubhankar Ghorai,Pijus Ghorai,Dipankar Bera et al.
Shubhankar Ghorai et al.
The development of fluorescent sugar hydrogels has addressed robust challenges in health safety, low cost, versatile functionality, and bio-inspired utilization for application purposes. Here, we introduce a fluorescent sugar hydrogel prepa...