Hypoxia-Responsive Polymersomes for Stemness Reduction in Patient-Derived Solid Tumor Spheroids [0.03%]
用于患者衍生的实体瘤球体干性降低的低氧响应型聚合物囊osomes
Connor Edvall,Narendra Kale,Sakurako Tani et al.
Connor Edvall et al.
Aggressive solid tumors are associated with rapid growth, early hypoxia, a lack of targeted therapies, and a poor prognosis. The hypoxic niches within the rapidly growing solid tumors give rise to a stem-cell-like phenotype with higher meta...
Twisted Molecular Core Conjugated Oxo-Ether as a Fluorescent Probe for Lipid-Droplets Bioimaging and Live Cancer Cell Discrimination [0.03%]
扭曲的分子骨架连接氧乙酰化物用作脂滴生物成像和活癌细胞鉴别的荧光探针
Shouvik Bhuin,Purbali Chakraborty,Perumal Yogeeswari et al.
Shouvik Bhuin et al.
In quest of a new working design for a photostable lipid-droplets (LDs) bioimaging probe, we herein unveil and demonstrate a twisted donor(naphthalene)-π-acceptor(dicyano) architecture linked with oxo/thioether functionality, where the pro...
From Unprintable Peptidic Gel to Unstoppable: Transforming Diphenylalanine Peptide (Fmoc-FF) Nanowires and Cellulose Nanofibrils into a High-Performance Biobased Gel for 3D Printing [0.03%]
从无法打印的肽凝胶到无坚不摧:将双苯丙氨酸肽(Fmoc-FF)纳米线和纤维素纳米纤维转化为高性能生物基3D打印凝胶
Feras Dalloul,J Benedikt Mietner,Dhanya Raveendran et al.
Feras Dalloul et al.
The growing interest in gel-based additive manufacturing, also known as three-dimensional (3D) gel-printing technology, for research underscores the crucial need to develop robust biobased materials with excellent printing quality and repro...
Enzyme-Mimetic Zwitterionic Microgel Coatings for Antifouling and Enhanced Antithrombosis [0.03%]
仿酶型两亲性微凝胶涂层在防污和抗血栓中的应用
Xueyu Wang,Zhuojun Yan,Mengmeng Yao et al.
Xueyu Wang et al.
Blood-contacting devices serve as a mainstay in clinical treatment, yet thrombosis remains a major cause of device failure and poses risks to patient health. In this study, we developed a diselenide cross-linker, N,N'-bis(methacryloyl)selen...
Anti-inflammatory Effect of Microwave-Assisted Opuntia humifusa Extract (MA-OHE) against DSS-Induced Colitis [0.03%]
微波辅助仙人掌提取物(MA-OHE)对DSS诱导的结肠炎的抗炎作用
Jeong-Yun Youn,Ju-Young Moon,Young-Chul Lee
Jeong-Yun Youn
Ulcerative colitis (UC), including chronic colitis, is characterized by severe inflammation and oxidative stress in the colon. This study investigated the therapeutic potential of microwave-assisted Opuntia humifusa extract (MA-OHE), prepar...
Self-Assembled of Multifunctional Fluorescent Copper-DNA Nanoflowers for Cell-Specific-Target MicroRNA Imaging [0.03%]
多功能荧光铜-DNA纳米花的自组装用于细胞特异性靶microRNA成像
Wenhao Dai,Tongtong Zhang,Fan Zhang et al.
Wenhao Dai et al.
The development of simple and versatile approaches for the fabrication of DNA-based composite nanomaterials, endowed with defined morphologies and specific functionalities, is of paramount importance for various applications. Herein, we rep...
Impact of Transportation on the Suitability of Cryopreserved Corneal Lenticule for Implantation [0.03%]
运输对冷冻保存的角膜透镜植入适应性的影响
Jenetta Y W Soo,Gabriel Tan,Evelina Han et al.
Jenetta Y W Soo et al.
Corneal lenticules can be deposited and retrieved for vision-restoring surgeries. Extended transportation logistical delays from the lenticule bank to the clinic could be a concern. To investigate this, corneal lenticules were cryopreserved...
Antianemic Activity, Inhibition of Oxidative Stress, and Iron Supplementation in Mice with Iron-Deficiency Anemia through HG-Hawthorn Pectin-Iron(III) Complexes [0.03%]
HG-山 Hawthorn果胶-铁(III)复合物通过抗贫血活性,抑制氧化应激和铁补充小鼠缺铁性贫血
Haocheng Zhang,Wenxian Sun,Jiawei Qi et al.
Haocheng Zhang et al.
In this study, we initially assessed the antioxidant activities of various HG-type hawthorn pectin-iron(III) complexes, which were synthesized in our previous research, utilizing methods such as reducing assay, 2,2-azino-bis-3-ethylbenzothi...
Transparent Biomaterial-Based Nonvolatile Bioelectronic Memory with Excellent Endurance [0.03%]
具有优异 endurance 的透明生物材料非易失性生物电子记忆体
Dimpal Kumari,Anurag Gupta,Karuna Kumari et al.
Dimpal Kumari et al.
With the recent upsurge of data-driven technology, the demand for storage elements has pushed the researchers to explore design of nobel nonvolatile memory devices with diverse functionalities. However, the management of electronic waste ha...
Maria V Shestovskaya,Anna L Luss,Olga A Bezborodova et al.
Maria V Shestovskaya et al.
This research aimed to evaluate the potency of preparation based on heparinized iron oxide nanoparticles (hIONPs) in combination with radiation therapy, including magnetic delivery via the applied magnetic field (AMF), in sarcoma and cervic...