Vitamin D3 Supplementation Modulates Inflammatory Protein CHI3L1/YKL-40 and Oxidative Stress Status in Multiple Sclerosis [0.03%]
维生素D3补充调节炎症蛋白CHI3L1/YKL-40和氧化应激在多发性硬化中的作用
Sevda Asadpour,Mehrdokht Mazdeh,Jamshid Karimi et al.
Sevda Asadpour et al.
Objective: Multiple sclerosis (MS) is characterized by chronic neuroinflammation and oxidative stress. Vitamin D is believed to exert immunomodulatory and antioxidant effects, yet its impact on specific inflammatory prote...
Clinical Trial
Neuropsychopharmacology reports. 2025 Dec;45(4):e70076. DOI:10.1002/npr2.70076 2025
Possible Involvement of Hallucinogenic Effects in the Aversive Effects Induced by Kappa-Opioid and 5-HT2A /2C Receptor Agonists in Mice [0.03%]
kappa-阿片受体和5-HT2A/2C受体激动剂致小鼠不良反应的幻觉效应参与作用的可能性
Hideaki Kato,Yoshimi Ichimaru,Masaaki Kurihara et al.
Hideaki Kato et al.
Aim: The regulation of new psychoactive and dangerous abused substances is very important for the prevention of drug abuse. A simple and effective evaluation method using laboratory animals is needed to regulate designate...
Gray Matter Alterations and Symptom Severity in Forensic Psychiatric Patients: An Exploratory VBM Study [0.03%]
精神症状严重程度与灰质变化在刑事精神病学病人中的相关性：一项探索性的VBM研究
Gaia Cartocci,Maddalena Boccia,Pieritalo Maria Pompili et al.
Gaia Cartocci et al.
Aim: The relationship between mental illness and criminal behavior is a critical social issue that remains under debate. This study aimed to investigate differences in cortical gray matter (GM) volume between mentally ill...
The Effectiveness of Herbal Mixture of Echium amoenum L. and Rheum ribes on Obsessive-Compulsive Disorder: A Randomized Controlled Triple-Blind Clinical Trial [0.03%]
红景天和毛脉千里光混合草药对强迫症疗效的随机对照临床试验
Ali Talaei,Ala Masiha,Fahimeh Afzaljavan et al.
Ali Talaei et al.
Objective: The use of complementary and alternative medicine has gained traction in the treatment of psychiatric disorders, including obsessive-compulsive disorder (OCD). This trial investigates the efficacy of an herbal ...
Randomized Controlled Trial
Neuropsychopharmacology reports. 2025 Dec;45(4):e70073. DOI:10.1002/npr2.70073 2025
Adrenal Insufficiency-Induced Delirium Following Gastrectomy in a Patient With Gastric Cancer Treated With Nivolumab, Immune Checkpoint Inhibitors: A Case Report [0.03%]
一例接受纳武利尤单抗免疫检查点抑制剂治疗的胃癌患者在行胃切除术后发生肾上腺功能不全性谵妄的病例报告
Kazuki Yamada,Taro Sasaki,Tamaki Owada et al.
Kazuki Yamada et al.
Background: Delirium is common after major surgery, yet endocrine causes such as adrenal insufficiency (AI) may be underrecognized, particularly in patients previously exposed to immune checkpoint inhibitors (ICIs); recen...
A Japanese Pregnant Woman With Treatment-Resistant Schizophrenia Who Continued Clozapine With Blood Concentration Monitoring During the Perinatal Period and Had a Healthy Baby: A Case Report [0.03%]
血药浓度监测下氯氮平全程不停药顺利分娩的治疗抵抗型妊娠合并精神分裂症患者一例报告
Mariko Tsukiji,Kaori Yamazaki,Yusuke Nakata et al.
Mariko Tsukiji et al.
Background: Clozapine is known to improve the social functioning of patients with treatment-resistant schizophrenia (TRS). In Japan, there are few reports on pregnancy and childbirth in patients treated with clozapine, an...
Sleep Architecture Alterations Following High-Dose Steroid Pulse Therapy: A Pilot Study Using a Portable Electroencephalogram-Based Device [0.03%]
高剂量糖皮质激素冲击治疗后的睡眠结构改变：便携式脑电图设备的试点研究
Hiroki Endo,Yuki Shigetsura,Misaki Chahara et al.
Hiroki Endo et al.
Background: Sleep disturbance is a common side effect of high-dose steroid pulse therapy (SPT). However, in clinical settings, the impact of this therapy on sleep architecture has not been objectively studied. ...
Letter to the Editor in Response to "Efficacy and Safety of Histamine H3 Receptor Antagonist/Inverse Agonist Including Betahistine for Schizophrenia: A Systematic Review and Meta-Analysis" by Nishii et al [0.03%]
写给Nishii等作者关于其系统回顾和荟萃分析论文的读者来信：贝塔司他治疗精神分裂症的疗效及安全性字母索引回应文章"Efficacy and Safety of Histamine H3 Receptor Antagonist/Inverse Agonist Including Betahistine for Schizophrenia: A Systematic Review and Meta-Analysis"
Muhammad Farhan
Muhammad Farhan
Long-Term Impact of EGUIDE Training on Facility-Wide Guideline Adherence Rate in Schizophrenia and Major Depressive Disorder: A Multicenter Study [0.03%]
EGUIDE培训对精神分裂症和抑郁症全程治疗指南依从率影响的多中心研究
Naomi Hasegawa,Hiroyuki Muraoka,Yusuke Arai et al.
Naomi Hasegawa et al.
Objective: The Effectiveness Research on the Dissemination and Education of Psychiatric Clinical Practice Guidelines (EGUIDE Project) was launched in Japan to promote guideline-adherent treatment for schizophrenia and maj...
Observational Study
Neuropsychopharmacology reports. 2025 Dec;45(4):e70067. DOI:10.1002/npr2.70067 2025
The Effect of N-Acetylcysteine (NAC) on Neurometabolites and Cognitive Function in Adults With Alcohol Use Disorder: A Preliminary Randomized Controlled Trial [0.03%]
N-乙酰半胱氨酸对成人酒精使用障碍患者神经代谢物及认知功能的影响：一项初步随机对照试验
Kristiane Yacou Dunbar,Gezelle Dali,Marilena M DeMayo et al.
Kristiane Yacou Dunbar et al.
Background and aims: Preclinical studies have demonstrated that N-acetylcysteine stabilizes levels of glutamate and glutathione and reduces alcohol-seeking behaviors, indicating it as a potential pharmacotherapy for the m...
Randomized Controlled Trial
Neuropsychopharmacology reports. 2025 Dec;45(4):e70066. DOI:10.1002/npr2.70066 2025