Lifestyle Factors and Current Alcohol Consumption Among Japanese Adolescents During the COVID-19 Pandemic: A Nationwide Cross-Sectional Study [0.03%]
日本青少年在COVID-19大流行期间的生活方式因素和当前饮酒情况：一项全国横断面研究
Masatake Nishiwaki,Hideyuki Kanda,Keita Yoshida et al.
Masatake Nishiwaki et al.
Background: The COVID-19 pandemic may have influenced drinking behaviors in minors by disrupting daily routines and increasing psychosocial stress, although alcohol use among Japanese adolescents has declined in recent ye...
Disruption of the l-DOPA Receptor Gpr143/OA1-Gene in Mice Creates a Unique Mixed Psychosis-Like Phenotype [0.03%]
小鼠的l-多巴受体Gpr143/OA1基因受损产生了一种独特的混合精神疾病样表型
Yoshio Goshima,Haruko Nakamura,Motokazu Koga et al.
Yoshio Goshima et al.
GPR143, originally identified as the gene product of ocular albinism 1 (OA1), a G protein-coupled receptor (GPCR), can function as a receptor for l-3,4-dihydroxyphenylalanine (DOPA), a precursor of dopamine (DA). To examine the physiologica...
Pharmacologic Treatment of Kleine-Levin Syndrome: A Case Report and Comprehensive Review of Therapeutic Options [0.03%]
Kleine-Levin综合征的药物治疗：病例报告和治疗方案综合评价
Sarisa Thawongit,Vorasith Siripornpanich,Lunliya Thampratankul
Sarisa Thawongit
Kleine-Levin syndrome (KLS) is a rare disorder with limited literature on treatment options and efficacy, especially in adolescents. We report a 12-year-old patient with KLS who had a favorable response to clarithromycin therapy. In this un...
Probiotic Supplementation and Executive Function in Children With Attention-Deficit/Hyperactivity Disorder [0.03%]
益生菌补充与注意缺陷多动障碍儿童的执行功能的关系
Abdolrahman Parhiz,Pegah Samani,Majid Kamali et al.
Abdolrahman Parhiz et al.
Background: Attention Deficit Hyperactivity Disorder (ADHD) is a prevalent neurodevelopmental condition marked by inattention, hyperactivity, and impulsivity, which substantially impacts children's academic and social per...
Randomized Controlled Trial
Neuropsychopharmacology reports. 2026 Mar;46(1):e70084. DOI:10.1002/npr2.70084 2026
Safety of Vortioxetine in Patients With Depression: A Post-Marketing Surveillance Study of Intracranial Hemorrhage in a Japanese Health Insurance Claims Database [0.03%]
抗抑郁药沃替西汀颅内出血真实世界研究——日本健康保险索赔数据库的药品上市后安全性监测报告
Takeshi Inoue,Rie Otake,Tatsuya Hoshino
Takeshi Inoue
Aim: As part of a post-marketing commitment, this study evaluated the incidences of intracranial hemorrhage and serious (intracranial or gastrointestinal) hemorrhage requiring hospitalization in Japanese patients with dep...
Evaluation of GABAergic and Glutamatergic Levels in the Dorsal Anterior Cingulate Cortex of Patients With Bipolar Disorder: A Cross-Sectional 1H-MRS Study [0.03%]
双相障碍患者背内侧前额叶皮层GABA和谷氨酸水平的评估：一项横向¹H-MRS研究
Sotaro Moriyama,Yoshihiro Noda,Shiori Honda et al.
Sotaro Moriyama et al.
Background: Imbalances between excitatory and inhibitory (E/I) neurotransmitters in the brain may contribute to the pathophysiology of bipolar disorder (BD). Proton magnetic resonance spectroscopy (1H-MRS) measures glutam...
Effect of the rs7858836 Single-Nucleotide Polymorphisms of the ASTN2 Gene on Pain-Related Phenotypes in Japanese Women Who Underwent Laparoscopic Gynecologic Surgery [0.03%]
ASTN2基因rs7858836单核苷酸多态性对日本女性腹腔镜妇科手术相关疼痛表型的影响
Rie Inoue,Daisuke Nishizawa,Shoko Okahara et al.
Rie Inoue et al.
Background: In our previous study, the minor T allele of the rs7858836 C/T single-nucleotide polymorphism (SNP) in the ASTN2 gene, which encodes astrotactin 2, was associated with reduced fentanyl requirements after lapar...
Possible Effect of Governmental Restrictions of Benzodiazepine Prescriptions on Suicide Attempts by Overdose of Prescribed Psychotropic Drugs in Japan [0.03%]
日本政府限制苯二氮卓类药物处方对日本因过量服用处方精神活性药物企图自杀的影响研究
Akihisa Akahane,Kenichi Matsumura,Yukari Mashiko et al.
Akihisa Akahane et al.
Purpose: Suicide attempt by overdose medication of benzodiazepine is common. In Japan, governmental restrictions on benzodiazepine multidrug use started as of 2012, resulting in a decrease in benzodiazepine prescriptions ...
Association Study on Multi-Timepoint DNA Methylation Levels of Serotonin Transporter Gene and Adolescent Psychological-Behavioral Development [0.03%]
五羟色胺转运基因多时间点DNA甲基化水平与青少年心理行为发育关联研究
Tempei Ikegame,Miki Bundo,Daiki Nagaoka et al.
Tempei Ikegame et al.
Aims: This study aimed to investigate whether multi-timepoint DNA methylation levels at the SLC6A4 gene during early adolescence are associated with psychopathological and behavioral clusters, SLC6A4 encodes the serotonin...
Longitudinal Associations of Serum Orexin-A With Physical Activity and Sleep in Schizophrenia: A Preliminary Study [0.03%]
有关睡眠和运动对精神分裂症患者血清食欲素水平影响的纵向研究初步报告
Akira Tanaka,Yusuke Arai,Takehiko Yasaki et al.
Akira Tanaka et al.
Aim: Orexin-A (OXA) is a neuropeptide that regulates arousal, behavior, and sleep-wake rhythms. While altered OXA levels have been observed in schizophrenia, longitudinal data are limited. This study examined the relation...