Aligning Measurement, Scoring, and Interpretation in Survey-Based NSSI Research [0.03%]
基于调查的NSSI研究中测量、评分和解释的一致性问题探究
Kenjiro Shiraishi
Kenjiro Shiraishi
This graphical abstract highlights the central interpretive point of the Letter: the survey measured public views about possible functions of NSSI, not the actual motives of people who engage in NSSI. Clearer alignment between measurement t...
Hydrogen Gas Therapy in Schizophrenia: Potential Neuroprotective Effects From an Animal Study [0.03%]
氢气气体疗法在精神分裂症中的潜在神经保护作用：一项动物研究的结果
Nobumi Miyake,Toshiaki Haga,Shin-Ichi Hirano et al.
Nobumi Miyake et al.
Aims: Oxidative stress has recently emerged as a key factor in the pathophysiology of schizophrenia. This study investigated whether inhalation therapy with hydrogen gas, a selective antioxidant, could reduce oxidative st...
Beyond Diagnosis: Transdiagnostic Cognitive Subgroups in Mood Disorders Linked to Work-Related Disability [0.03%]
超越诊断：情绪障碍中与工作相关残疾相连的跨诊断认知亚群
Ryo Sawagashira,Takuro Tsutsumi,Hayato Watanabe et al.
Ryo Sawagashira et al.
Aim: Cognitive dysfunction is a transdiagnostic feature of mood disorders and a key determinant of functional outcomes. This study aimed to identify transdiagnostic cognitive heterogeneity among patients with mood disorde...
Effects of Histamine H3 Receptor Antagonist/Inverse Agonist Pitolisant on Temporal Prediction, Spatial Switching, and Spontaneous Locomotion in Mice [0.03%]
新型组胺H3受体拮抗剂/反向激动剂Pitolisant对小鼠时间预测、空间转换和自发运动的影响研究
Shohei Kaneko,Kazuko Hayashi,Kota Yamada et al.
Shohei Kaneko et al.
Histamine receptors contribute to a wide range of brain functions, including arousal, motivation, attention, and memory, but their causal involvement in switching behavior remains insufficiently understood. Here, we examined the effects of ...
Clinical Characteristics of Over-The-Counter Drug Misusers in Psychiatric Practice in Japan: Comparison by Type of Drug Misused for the First Time [0.03%]
日本精神医学实践中滥用非处方药患者的临床特征：首次滥用的药物类型比较
Soichiro Omiya,Yuko Tanibuchi,Takashi Usami et al.
Soichiro Omiya et al.
Purpose: This study aimed to understand the clinical characteristics of individuals who misuse over-the-counter (OTC) drugs in psychiatric clinical settings in Japan, and to reconsider approaches to current drug misuse pr...
Comparative Study
Neuropsychopharmacology reports. 2026 Jun;46(2):e70108. DOI:10.1002/npr2.70108 2026
Japanese Cohort Study and Meta-Analysis Demonstrate Significant Association Between Serotonin Transporter-Linked Polymorphic Region and Schizophrenia [0.03%]
日本前瞻性队列研究和Meta分析证实5-HTTLPR与精神分裂症显著相关
Masao Miyachi,Toshiyuki Shirai,Shohei Okada et al.
Masao Miyachi et al.
Schizophrenia is a prevalent psychiatric disease that substantially affects health and increases mortality risk. The 5-hydroxytryptamine system has been implicated in its pathogenesis. The SLC6A4 gene encodes the serotonin transporter, whic...
Association Between Psychiatrists' Subjective Clinical Behavior Scores and Objective Quality Indicators Based on Discharge Prescriptions: A Nationwide Multicenter Study Based on the EGUIDE Project [0.03%]
基于出院处方的客观质量指标的精神科医生主观临床行为评分的相关性研究：EGUIDE项目多中心全国研究
Kazuhiko Yamamuro,Naomi Hasegawa,Yusuke Arai et al.
Kazuhiko Yamamuro et al.
Aim: Psychiatrists often perceive their clinical practices as guideline-concordant; however, discrepancies frequently exist between perceived and actual prescribing behaviors. To explore this gap, we examined the associat...
Observational Study
Neuropsychopharmacology reports. 2026 Jun;46(2):e70110. DOI:10.1002/npr2.70110 2026
Differential Neuronal Development in iPSC-Derived Neural Stem Cells From Monozygotic Twin Cases With Treatment-Resistant Schizophrenia and Discordant Responses to Clozapine [0.03%]
来自难治性精神分裂症单卵双胞胎病例的诱导多能干细胞来源的神经干细胞发育差异及对氯氮平的不同反应
Shotaro Kawano,Sayaka Katayama,Masaya Ogawa et al.
Shotaro Kawano et al.
Treatment-resistant schizophrenia (TRS) affects 20%-30% of individuals diagnosed with schizophrenia and is effectively managed with clozapine. However, the molecular and cellular mechanisms that underlie its efficacy remain largely unclear....
Combination Versus Monotherapy in Acute Anti-LGI1 Encephalitis: A Real-World Dose Optimization Analysis [0.03%]
急性抗LGI1脑炎联合疗法与单药治疗的疗效对比：真实世界剂量优化分析
Yao Tan,Ming Sun,Qinqin Liu et al.
Yao Tan et al.
Background: Anti-leucine-rich-glioma-inactivated 1 encephalitis (LGI1e) predominantly affects older adults, who frequently present with chronic comorbidities. Given their heightened susceptibility to adverse effects, opti...
Comparative Study
Neuropsychopharmacology reports. 2026 Jun;46(2):e70112. DOI:10.1002/npr2.70112 2026
Serum Amyloid β Oligomer May Predict Treatment Response in Middle-Aged and Late-Life Patients With Depression [0.03%]
血清淀粉样β寡聚体或可预测中年和老年人抑郁患者的治疗反应
Kentaro Shimizu,Seita Yasuda,Hitoshi Maeshima et al.
Kentaro Shimizu et al.
Aim: Late-life patients with depression are reportedly less responsive to antidepressant treatment than younger patients. Additionally, patients who have depression comorbid with Alzheimer's disease (AD) and those with an...
Observational Study
Neuropsychopharmacology reports. 2026 Jun;46(2):e70109. DOI:10.1002/npr2.70109 2026