Insulin resistance spawns hypertriglyceridemia-induced acute pancreatitis and diabetic ketoacidosis: an evolving metabolic cascade [0.03%]
胰岛素抵抗诱发的高甘油三酯血症急性胰腺炎和糖尿病酮酸中毒代谢级联反应
Chaoneng Wu,Apoorv Tiwari,Maxim Zlatopolsky et al.
Chaoneng Wu et al.
Insulin resistance (IR) is associated with uncontrolled lipolysis, leading to the release of free fatty acids, ectopic fat accumulation, and hypertriglyceridemia (HTG). Adipose IR is the primary factor contributing to severe HTG, which inte...
High sensitivity C-reactive protein subsequent rise in urine albumin/creatinine ratio/fall in estimated glomerular filtration rate over 24 years in people with type 2 diabetes [0.03%]
2型糖尿病患者高敏C反应蛋白升高的后续尿白蛋白/肌酐比值升高/肾小球滤过率估算值下降的24年前瞻性研究
Sangeeth Veulchamy,Andreas Matheou,Orestis Zavlis et al.
Sangeeth Veulchamy et al.
Systemic inflammation, which can be measured by high-sensitivity C-reactive protein (hsCRP), may play a crucial role in the progression of chronic kidney disease (CKD) in people with type 2 diabetes (T2D). In this study, we report longitudi...
Composite risk of cardiovascular disease comorbidity in people living with diabetes in Africa [0.03%]
非洲糖尿病患者心血管疾病并发风险的综合评估
Regina Idu Ejemot-Nwadiaro,Divine-Favour Chichenim Ofili,Stephen Chukwuma Ogbodo et al.
Regina Idu Ejemot-Nwadiaro et al.
Aim: Despite the high likelihood of comorbidity from shared risk factors, the cardiovascular disease (CVD) risk, based on the combined presence of key risk factors, in people with diabetes mellitus is poorly understood. T...
Glucagon-like peptide-1 receptor agonists and obesity paradox in heart failure with preserved ejection fraction: a systematic review [0.03%]
胰高血糖素样肽-1受体激动剂与射血分数保留的心力衰竭中肥胖悖论的系统评价研究
Darshan Hullon,Karolina Janiec,Violetta Florova et al.
Darshan Hullon et al.
Heart failure with preserved ejection fraction (HFpEF) is associated with obesity, inflammation, and cardiac metabolism. While obesity contributes to HFpEF, the 'obesity paradox' suggests that higher BMI may correlate with better outcomes. ...
BRIDGE-DS study: a multicenter, observational, retrospective analysis of dapagliflozin and sitagliptin combination on modifiable cardiovascular risk factors in T2DM patients with ASCVD or high cardiovascular risk [0.03%]
BRIDGE-DS研究：二甲双胍疗效观察性研究：达格列净联合西格列汀对T2DM合并动脉粥样硬化性心血管疾病或高心血管风险患病人群的心血管危险因素的多中心、观察性、回顾性分析
Naveen Bhamri,Ashutosh Kumar,Chandrakant Mishra et al.
Naveen Bhamri et al.
Background: Atherosclerotic cardiovascular disease (ASCVD) is a major comorbidity among those with type 2 diabetes mellitus (T2DM) and requires effective management strategies. Few real-world evidence studies have establi...
Improved cardiovascular outcomes with glucagon-like peptide-1 receptor agonists - what is the role of weight reduction? [0.03%]
GLP-1受体激动剂改善心血管结局的作用与减重有关吗？
Stephan Jacob,Robert H Eckel,Andrew J Krentz
Stephan Jacob
BRIDGE-DS study: evaluating the effectiveness and safety of dapagliflozin/sitagliptin combination in type 2 diabetes mellitus patients with heart failure [0.03%]
BRIDGE-DS研究：评估达格列净/西格列汀在合并心力衰竭的2型糖尿病患者中的疗效和安全性
Kandanat Purushothaman Nair Suresh Kumar,Manikandan Thiruvanath Variam,Bala Vignesh S et al.
Kandanat Purushothaman Nair Suresh Kumar et al.
Background: Co-occurrence of type 2 diabetes mellitus (T2DM) and heart failure (HF) elevates the risk of morbidity and mortality. Recent research emphasizes treatment strategies that go beyond glycemic control to enhance ...
Genetic, neuropeptidergic, and cardiometabolic interplay in female central precocious puberty [0.03%]
中枢性女性早熟的遗传、神经肽和心血管代谢相互作用
Aygun Khaleddin Musayeva,Mahira Firudinkizi Amirova
Aygun Khaleddin Musayeva
Central precocious puberty (CPP) results from premature reactivation of the hypothalamic-pituitary-gonadal axis and is increasingly recognized as a systemic condition linked to cardiometabolic health. Genetic mutations, particularly in impr...
Effects of obstructive sleep apnea on vascular structure and function in adults with obesity and type 2 diabetes: a comparative study [0.03%]
肥胖合并2型糖尿病成人中阻塞睡眠呼吸暂停对血管结构和功能的影响：一项对比研究
Kanpiraya Nithitsutthibuta,Nuntigar Sonsuwan,Sureeporn Uthaikhup et al.
Kanpiraya Nithitsutthibuta et al.
Introduction: Obstructive sleep apnea (OSA) and type 2 diabetes (T2D) are common in adults with obesity, both contributing to vascular dysfunction and increased cardiovascular risk. In individuals with obesity, OSA is ass...
Utilizing natriuretic peptides for predicting heart failure risk following myocardial infarction [0.03%]
应用利钠肽预测心肌梗死后的心力衰竭风险
Ganchimeg Ulziisaikhan,Mungun-Ulzii Khurelbaatar,Chingerel Khorloo et al.
Ganchimeg Ulziisaikhan et al.
Background: In Mongolia, ischemic heart disease, specifically acute myocardial infarction (AMI), is a significant etiology of chronic heart failure (HF). Therefore, early recognition of the risk of HF following AMI is cri...