Probiotic supplementation and postoperative antioxidant response in patients undergoing open‑heart surgery: a randomized controlled trial [0.03%]
益生菌补充对心脏手术患者术后抗氧化反应的影响：一项随机对照试验
Fatemeh Mofidi,Sahar Kavand,Saeid Doaei et al.
Fatemeh Mofidi et al.
Background: Oxidative stress is a major contributor to postoperative complications in patients undergoing open-heart surgery. Probiotics have been suggested to enhance antioxidant defenses by modulating gut microbiota and...
Autonomic dysfunction and insulin resistance in type 2 diabetes mellitus with hypoglycemia unawareness: an observational study [0.03%]
糖尿病低血糖无觉察症的自主神经功能障碍与胰岛素抵抗：一项观察性研究
Debarshi Nandi,Supriya Gupta,Nasar Ajmera et al.
Debarshi Nandi et al.
Purpose: To evaluate the association between hypoglycemia unawareness, cardiac autonomic function, and insulin resistance in individuals with type2 diabetes, and explore potential correlations between autonomic dysfunctio...
Pulse wave velocity is elevated in people with serious mental illness with vascular age advanced in two-thirds of individuals [0.03%]
脉搏波速度升高，伴有血管年龄提前胩患者的三分之二中
Adrian H Heald,Sangeeth Veluchamy,Karen Barchetti et al.
Adrian H Heald et al.
Introduction: People with serious mental illness (SMI) have a higher than average cardiovascular event rate/shortened life expectancy by up to 20 years. The higher incidence of cardiovascular events is not sufficiently ac...
Genetic evidence for the causal relationship between metabolic diseases and primary aldosteronism: insights from Mendelian randomization analysis [0.03%]
基因证据证明代谢性疾病与原发性醛固酮增多症之间存在因果关系：来自孟德尔随机化分析的启示
Huan Zhang,Zixin Lin,Wei Tian et al.
Huan Zhang et al.
Purpose: Although the relationship between metabolic diseases and primary aldosteronism has been recognized for years, the causal relationship between them remains unclear. Therefore, our study aimed to clarify this uncer...
Insulin resistance spawns hypertriglyceridemia-induced acute pancreatitis and diabetic ketoacidosis: an evolving metabolic cascade [0.03%]
胰岛素抵抗诱发的高甘油三酯血症急性胰腺炎和糖尿病酮酸中毒代谢级联反应
Chaoneng Wu,Apoorv Tiwari,Maxim Zlatopolsky et al.
Chaoneng Wu et al.
Insulin resistance (IR) is associated with uncontrolled lipolysis, leading to the release of free fatty acids, ectopic fat accumulation, and hypertriglyceridemia (HTG). Adipose IR is the primary factor contributing to severe HTG, which inte...
High sensitivity C-reactive protein subsequent rise in urine albumin/creatinine ratio/fall in estimated glomerular filtration rate over 24 years in people with type 2 diabetes [0.03%]
2型糖尿病患者高敏C反应蛋白升高的后续尿白蛋白/肌酐比值升高/肾小球滤过率估算值下降的24年前瞻性研究
Sangeeth Veulchamy,Andreas Matheou,Orestis Zavlis et al.
Sangeeth Veulchamy et al.
Systemic inflammation, which can be measured by high-sensitivity C-reactive protein (hsCRP), may play a crucial role in the progression of chronic kidney disease (CKD) in people with type 2 diabetes (T2D). In this study, we report longitudi...
Composite risk of cardiovascular disease comorbidity in people living with diabetes in Africa [0.03%]
非洲糖尿病患者心血管疾病并发风险的综合评估
Regina Idu Ejemot-Nwadiaro,Divine-Favour Chichenim Ofili,Stephen Chukwuma Ogbodo et al.
Regina Idu Ejemot-Nwadiaro et al.
Aim: Despite the high likelihood of comorbidity from shared risk factors, the cardiovascular disease (CVD) risk, based on the combined presence of key risk factors, in people with diabetes mellitus is poorly understood. T...
Glucagon-like peptide-1 receptor agonists and obesity paradox in heart failure with preserved ejection fraction: a systematic review [0.03%]
胰高血糖素样肽-1受体激动剂与射血分数保留的心力衰竭中肥胖悖论的系统评价研究
Darshan Hullon,Karolina Janiec,Violetta Florova et al.
Darshan Hullon et al.
Heart failure with preserved ejection fraction (HFpEF) is associated with obesity, inflammation, and cardiac metabolism. While obesity contributes to HFpEF, the 'obesity paradox' suggests that higher BMI may correlate with better outcomes. ...
BRIDGE-DS study: a multicenter, observational, retrospective analysis of dapagliflozin and sitagliptin combination on modifiable cardiovascular risk factors in T2DM patients with ASCVD or high cardiovascular risk [0.03%]
BRIDGE-DS研究：二甲双胍疗效观察性研究：达格列净联合西格列汀对T2DM合并动脉粥样硬化性心血管疾病或高心血管风险患病人群的心血管危险因素的多中心、观察性、回顾性分析
Naveen Bhamri,Ashutosh Kumar,Chandrakant Mishra et al.
Naveen Bhamri et al.
Background: Atherosclerotic cardiovascular disease (ASCVD) is a major comorbidity among those with type 2 diabetes mellitus (T2DM) and requires effective management strategies. Few real-world evidence studies have establi...
Improved cardiovascular outcomes with glucagon-like peptide-1 receptor agonists - what is the role of weight reduction? [0.03%]
GLP-1受体激动剂改善心血管结局的作用与减重有关吗？
Stephan Jacob,Robert H Eckel,Andrew J Krentz
Stephan Jacob