Enhancement of adipose stem cell quality via Cu-MON: Transcriptome and bioinformatics analysis of normal and diabetic stem cells [0.03%]
通过Cu-MON提高脂肪干细胞的质量：正常和糖尿病干细胞的转录组和生物信息学分析
Ruixin Pang,Kaijing Liu,Biou Liu et al.
Ruixin Pang et al.
Transplanted adipose stem cells (ASC) have a low survival rate in the body, and there are not many ASC that can be effectively used, which weakens their tissue repair function. Based on this status quo, a new type of copper-based metal-orga...
The role of amylin, a gut-brain axis hormone, in metabolic and neurological disorders [0.03%]
肠道-大脑轴激素calcitonin基因相关肽在代谢和神经性疾病中的作用
Tahir Muhammad,Stephen F Pastore,Katrina Good et al.
Tahir Muhammad et al.
Amylin, also known as islet amyloid polypeptide (IAPP), is a pancreatic β-cell peptide hormone involved in satiation and control food intake. It is also produced in smaller quantities by neurons, the gastrointestinal tract, and spinal gang...
Lía Hoz Rodríguez,Maricela Santana Vázquez,Luis Fernando Ramírez González et al.
Lía Hoz Rodríguez et al.
A pentapeptide AVIFM (CAP-p5) derived from the carboxy-terminus end of cementum attachment protein was examined for its role on proliferation, differentiation, and mineralization of human periodontal ligament cells (HPLC), and for its poten...
The human-specific noncoding RNA RP11-424G14.1 functions at the intersection of sexually dimorphic pathways in inflammation, senescence, and metabolism [0.03%]
人特有的非编码RNA RP11-424G14.1在炎症、衰老和代谢的性别二态通路中发挥作用
Kameron Kennicott,Yun Liang
Kameron Kennicott
Sexual dimorphism is a fundamental characteristic of various physiological and pathological processes in humans, including immune responses, senescence, and metabolism. Most studies on the sex bias have focused on sex hormones or female-bia...
Yi Zhang,Wanlin Xie,Xicui Zong et al.
Yi Zhang et al.
Despite therapeutic improvements in prostate cancer treatment, the recurrence and mortality rates are still high, and the underlying mechanisms still need further study. Non-SMC Condensin II Complex Subunit D3 (NCAPD3) is a subunit of conde...
tPA-GFP is a reliable probe for detecting compound exocytosis in human pancreatic β-cells [0.03%]
tPA-GFP可作为检测人类胰岛β细胞化合物分泌的可靠探针
Aishwarya A Makam,Shruti Sharma,Prajwal Nagle et al.
Aishwarya A Makam et al.
Pancreatic β-cells secrete insulin stored in large dense core vesicles (LDCV) by fusion of vesicle and plasma membrane during a process called insulin exocytosis. Insulin secretion is biphasic with a fast first phase and a sustained second...
6-Nitrodopamine potentiates catecholamine-induced contractions of human isolated vas deferens [0.03%]
6-硝基多巴胺增强去甲肾上腺素对人精索平滑肌的收缩作用
Antonio Tiago Lima,Sami Jabbour,José Britto-Júnior et al.
Antonio Tiago Lima et al.
6-Nitrodopamine (6-ND) is the main catecholamine released from human isolated vas deferens and the adrenergic nervous system is known to play a major role in the contractions of the epididymal portion of the vas deferens. Here it was invest...
Diacylglycerol kinase δ is required for skeletal muscle development and regeneration [0.03%]
二酰基甘油激酶δ是骨骼肌发育和再生所必需的
Hiromichi Sakai,Chiaki Murakami,Mayumi Takechi et al.
Hiromichi Sakai et al.
Diacylglycerol kinase δ (DGKδ) phosphorylates diacylglycerol to produce phosphatidic acid. Previously, we demonstrated that down-regulation of DGKδ suppresses the myogenic differentiation of C2C12 myoblasts. However, the myogenic roles o...
Di Hu,Zisha Yang,Jun-Ai Zhang et al.
Di Hu et al.
Copper is a vital trace element crucial for mediating interactions between Mycobacterium and macrophages. Within these immune cells, copper modulates oxidative stress responses and signaling pathways, enhancing macrophage immune functions a...
Fluorescent identification of axons, dendrites and soma of neuronal retinal ganglion cells with a genetic marker as a tool for facilitating the study of neurodegeneration [0.03%]
一种遗传标志物在神经元视网膜节细胞轴突、树突和胞体的荧光鉴别中的应用：促进神经系统变性研究的新工具
Puttipong Sripinun,Wennan Lu,Sergei Nikonov et al.
Puttipong Sripinun et al.
This study characterizes a fluorescent Slc17a6-tdTomato neuronal reporter mouse line with strong labeling of axons throughout the optic nerve, of retinal ganglion cell (RGC) soma in the ganglion cell layer (GCL), and of RGC dendrites in the...