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期刊名:Jor spine

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ISSN:2572-1143

e-ISSN:2572-1143

IF/分区:3.9/Q1

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共收录本刊相关文章索引526条
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Haiyan Sun,Mingwei He,Jinlei Pang et al. Haiyan Sun et al.
Background: Intervertebral disc degeneration (IDD) is a widespread issue associated with chronic lumbar pain and disability. This study aimed to identify lactate metabolism-related genes in IDD and elucidate their mechani...
Neharika Bhadouria,Justin Tiao,Angelica Baburova et al. Neharika Bhadouria et al.
Background: Intervertebral disc degeneration (IVDD) is a major cause of global disability that increases with age. IVD age may affect its injury susceptibility, yet few studies examine spine biomechanical changes with age...
Ippei Watanabe,Ko Takeda,Taiichi Shirogane Ippei Watanabe
Background: Condoliase is a treatment for lumbar disc herniation. This enzyme exerts its medicinal effects by digesting chondroitin sulfate (CS), which is abundant in the nucleus pulposus. However, the behavior of adminis...
Andrea Cina,Miklovana Tuci,Ferran Pellisé et al. Andrea Cina et al.
Background: Accurate computation of radiological parameters related to spinal alignment is clinically crucial for diagnosing and managing conditions, such as adolescent idiopathic scoliosis and adult spinal deformities. K...
Anja Stirnimann,Leon Schlagenhof,Benjamin Gantenbein et al. Anja Stirnimann et al.
Background: Intervertebral disc (IVD) degeneration (IDD) contributes to global disability and involves incompletely understood molecular processes. Recent advances in omics technologies help to unravel the complex biology...
Taylor J Bader,Manmeet Dhiman,Lucas Lo Vercio et al. Taylor J Bader et al.
Background: Stability of the spine and intervertebral disc (IVD) integrity is enabled by the highly organized fibrocartilaginous annulus fibrosus (AF). The shear properties of the AF are important in maintaining IVD integ...
Madison M Buckles,Abdulkadir Nur,Nada H Warda et al. Madison M Buckles et al.
Background: The nucleus pulposus (NP) in the intervertebral disc (IVD) is the first structure to exhibit degenerative changes during IVD degeneration (IDD). Currently, micro-computed tomography (micro-CT) imaging of the N...
Ravij Mehta,Sarthak Mohanty,Andrew Parker Hallmark et al. Ravij Mehta et al.
Background: Aging is a major risk factor for IVD degeneration and chronic lower back pain. Comparing degenerative patterns in human and mice, a commonly used pre-clinical model, is crucial for validating it in preclinical...
Richard D Bell,Evie C Reddick,David J Lillyman et al. Richard D Bell et al.
Background: Preclinical models of disc degeneration are important tools to discover disease pathology. Histopathology is often used to understand these changes, but analyses remain reliant on pathologists or graders using...