A Conceptual Review of Naturally Occurring Toxins and Venoms as Peptide Blockers to Combat Chronic Low Back Pain [0.03%]
天然毒素和毒液中肽阻滞剂的理论回顾及其在慢性下背痛治疗中的应用
James Melrose,Stone Sima,Neha Chopra et al.
James Melrose et al.
Background: One of the significant putative causes of low back pain (LBP) is degeneration of the intervertebral disc (IVD). Degenerated discs exhibit loss of proteoglycans, notably aggrecan, leading to mechanical dysfunct...
Relationship Between Quantitative MRI and Radiological, Histological, and Biochemical Measures of Intervertebral Disc Health in Client-Owned, Nonchondrodystrophic-Breed Dogs [0.03%]
定量磁共振成像与客户拥有的非软骨发育不良犬种椎间盘健康放射学、组织学和生化测量之间的关系
Alaina L Falck,Erick O Buko,Kayla L Chase et al.
Alaina L Falck et al.
Background: Client-owned dogs presenting clinically with intervertebral disc disease (IVDD) are a potential comparative animal model to help advance the understanding of disc degeneration and its treatment. To utilize dog...
Patient-Reported Outcomes Among an Observational Cohort of Individuals With Chronic Low Back Pain [0.03%]
慢性下腰痛患者的结局指标：观察性队列中的结果分析
Carol M Greco,Nathan E Dodds,Amanda M Acevedo et al.
Carol M Greco et al.
Background: Chronic low back pain (cLBP) is complex, disabling, and costly to patients and to society. Patients' social circumstances, beliefs, and behaviors interact in a dynamic way with biomedical factors and have the ...
Comments on "Exploring the Therapeutic Potential of Puerarin on Intervertebral Disc Degeneration by Regulating Apoptosis of Nucleus Pulposus Cells" [0.03%]
有关“探究地奥茋治疗椎间盘退变的作用机制及对髓核细胞凋亡的调控作用”的几点评论
Ji Jin,Miao Liu,Jiajie Guo et al.
Ji Jin et al.
Editorial
JOR spine. 2025 Aug 12;8(3):e70099. DOI:10.1002/jsp2.70099 2025
Feasibility of Physical Exam and Performance-Based Tests in Individuals With Chronic Low Back Pain: A Descriptive Study [0.03%]
慢性下腰痛患者体格检查和基于表现测试的可行性：一项描述性研究
Sara R Piva,Zakiy Alfikri,William Anderst et al.
Sara R Piva et al.
Background: Despite the wide utilization of physical tests and pain assessments to evaluate individuals with chronic low back pain (cLBP), there is limited information about their feasibility in terms of test duration, th...
Central Pattern Generators in Spinal Cord Injury: Mechanisms, Modulation, and Therapeutic Strategies for Motor Recovery [0.03%]
脊髓损伤中的中央模式发生器：运动恢复的机制、调控和治疗策略
Hao Su,Longfei Jing,Dongmei Lv et al.
Hao Su et al.
Background: Spinal cord injury (SCI) compromises the communication between the brain and spinal circuits involved in locomotion, resulting in severe motor dysfunction. However, currently available therapies have limited e...
Gait Analysis During Paralysis Recovery in a Rat Incomplete Spinal Cord Injury Model [0.03%]
不完全性脊髓损伤大鼠模型的偏瘫恢复期步态分析研究
Misa Toyota,Shion Masuda,Daiki Nohara et al.
Misa Toyota et al.
Background: In this study, we aimed to create a rat model of incomplete spinal cord injury and to determine the relationship between muscle tone and gait characteristics during recovery from paralysis. This necessity stem...
Spatial and Diurnal Variations in Sodium Content Within Intervertebral Disc Tissue [0.03%]
椎间盘组织中钠含量的时空变化规律
Jordin T Marshall,Anthony D Lutton,Mark W Grinstaff et al.
Jordin T Marshall et al.
Background: Daily cycles in tissue osmolarity within the intervertebral disc (IVD) are a biophysical signal that regulates cellular metabolism and arise from deformation of the charged and hydrated extracellular matrix (E...
Comparative Performance of Calcium Phosphate Grafts and Iliac Crest Autograft in Posterolateral Spinal Fusion in Rabbits [0.03%]
兔腰椎后外侧融合中磷酸钙骨替代材料与髂骨自体移植的比较研究
William R Walsh,Rema A Oliver,Matthew H Pelletier et al.
William R Walsh et al.
Background: Calcium phosphate (CaP) biomaterials are widely used in surgical applications such as spinal fusion to substitute for or extend autogenous bone graft. Preclinical testing in standardized animal models is usefu...
Development and Validation of a Machine Learning-Based Online Prognostic Model for Cervical Spondylosis Patients After Anterior Cervical Discectomy and Fusion: A Multicenter Study [0.03%]
基于机器学习的颈椎病患者前路颈椎间盘切除融合术后在线预后模型的开发与验证：一项多中心研究
Sitan Feng,Shengsheng Huang,Zhongxian Zhou et al.
Sitan Feng et al.
Background: Cervical spondylosis (CS) is a degenerative condition often requiring surgical intervention, such as anterior cervical discectomy and fusion (ACDF), to alleviate symptoms. However, postoperative outcomes can v...