Larger Lumbar Vertebral Body Osteophyte Volume Is Associated With Older Age and a More Caudal Vertebral Level in Individuals With Chronic Low Back Pain [0.03%]
较大的腰椎骨体积与慢性下背痛患者的年龄较大和较低的椎体水平有关
Clarissa LeVasseur,Sabreen Megherhi,Matthew Mesoros et al.
Clarissa LeVasseur et al.
Background: Chronic low back pain (cLBP) is often accompanied by changes in lumbar spine bony morphology, including osteophyte growth. Knowledge of the volume and location of osteophytes could provide insight into habitua...
From Concept to Clinic: Pre-Clinical Testing and Regulatory Considerations in Spine Implant Development [0.03%]
从概念到临床：脊柱植入物开发的前临床测试和监管考量
Amit Benady,Jerrin Thadathil Varghese,Ryan David Quarrington et al.
Amit Benady et al.
Background: Spinal implant development demands integration of biomechanical rigor with regulatory compliance. For surgeons, researchers, and biomedical engineers engaged in translational research, understanding the regula...
A Decade of Leadership and Impact: Celebrating 10 Years of the ORS Spine Section [0.03%]
脊柱节段十年来的发展与影响：庆祝ORS脊柱节段成立十周年纪念日
Neharika Bhadouria,Rahul Gawri,Gabriela Graziani et al.
Neharika Bhadouria et al.
Editorial
JOR spine. 2026 Apr 13;9(2):e70180. DOI:10.1002/jsp2.70180 2026
Inhibition of PLA2G15 Alleviates Palmitic Acid-Induced Lysosomal Membrane Permeabilization in Human Nucleus Pulposus Cells During Intervertebral Disc Degeneration [0.03%]
PLA2G15抑制缓解棕榈酸诱导的人髓核细胞椎间盘退变过程中溶酶体膜渗透性增高现象
Liqun Duan,Jiang Jiang,Shuangshuang Tu et al.
Liqun Duan et al.
Objective: Intervertebral disc degeneration (IDD) imposes substantial economic and healthcare burdens, yet its mechanisms remain incompletely understood and effective pharmacological treatments are lacking. This study aim...
Severity Prediction of Traumatic Cervical Spinal Cord Injury With an AI Model Based on MRI Radiomics [0.03%]
基于MRI影像组学的AI预测创伤性颈椎脊髓损伤严重程度
Chunshuai Wu,Chaochen Li,Guanhua Xu et al.
Chunshuai Wu et al.
Background: Traumatic cervical spinal cord injury (TCSCI) often leads to significant patient paralysis. Current clinical diagnosis relies heavily on empirical interpretation of magnetic resonance imaging (MRI) and the Ame...
Mechanosensitive Ion Channel PIEZO1 Suppresses BMP2-Induced Ossification of the Annulus Fibrosus Cells [0.03%]
机械敏感性离子通道PIEZO1通过抑制BMP2诱导的纤维环细胞骨化发挥止痛作用
Hisakazu Shitozawa,Ryo Nakamichi,Aki Yoshida et al.
Hisakazu Shitozawa et al.
Objective: Major cause of low-back pain is intervertebral disc degeneration (IVDD), with mechanical stress playing a crucial role in its progression. A mechanosensitive ion channel, PIEZO1, is involved in various musculos...
Chondroitinase Versus Papain Digestion Leads to Different Outcome for In Vitro Simulation of Degenerated Discs [0.03%]
chondroitinase与木瓜蛋白酶消化法体外模拟退变椎间盘的不同作用
Jan Ulrich Jansen,Graciosa Quelhas Teixeira,Elias Salzer et al.
Jan Ulrich Jansen et al.
Background: Biomaterials play an increasing role in intervertebral disc regeneration and require preclinical testing, typically performed using organ culture and in vitro models. Native human discs are limited, and animal...
Comparing Movement Patterns and Physical Function Between Chronic Low Back Pain Patients With Nociplastic and Nociceptive Pain Categories [0.03%]
比较 nociplastic 和 nociceptive慢性下腰痛患者的运动模式和物理功能特征
Erin Archibeck,Nicholas Harris,Patricia Zheng et al.
Erin Archibeck et al.
Background: Individuals with chronic low back pain (LBP) often present with significant physical dysfunction. The underlying cause is difficult to diagnose due to the heterogeneous nature of LBP categories. ...
Advancing Basic and Preclinical Spine Research: Highlights From the ORS PSRS 7th International Spine Research Symposium [0.03%]
第六届ORS-PSRS国际脊柱研究研讨会报告：推动基础和临床前期脊柱疾病的研究进展
Chitra L Dahia,Lachlan J Smith,Makarand V Risbud et al.
Chitra L Dahia et al.
The seventh biennial ORS-PSRS International Spine Research Symposium was held from November 10-14, 2024, at Skytop Lodge in Pennsylvania, USA. Jointly organized by the PSRS and ORS, the meeting brought together over 195 participants from 13...
Editorial
JOR spine. 2026 Feb 19;9(1):e70161. DOI:10.1002/jsp2.70161 2026
Reliability of Ultrasonography to Assess Spinal Compression During Heavy Load Carriage [0.03%]
超声检查评估负重时脊柱压缩可靠性的研究
Sherrilyn Walters,Ben Hoffman,Celeste E Coltman et al.
Sherrilyn Walters et al.
Background: Back pain and spinal injury are leading contributors to premature retirement, particularly in physically demanding occupations. Direct and practical methods of spinal assessment are needed to evaluate interven...