Internet-Based Abnormal Chromosomal Diagnosis During Pregnancy Using a Noninvasive Innovative Approach to Detecting Chromosomal Abnormalities in the Fetus: Scoping Review [0.03%]
基于互联网的妊娠期异常染色体筛查：用于检测胎儿染色体异常的创新非侵入式方法：循证卫生技术评估框架综述
Mega Obukohwo Sr Oyovwi,Ejiro Peggy Ohwin,Rume Arientare Rotu et al.
Mega Obukohwo Sr Oyovwi et al.
Background: Chromosomal abnormalities are genetic disorders caused by chromosome errors, leading to developmental delays, birth defects, and miscarriages. Currently, invasive procedures such as amniocentesis or chorionic ...
Comparison of the Neutralization Power of Sotrovimab Against SARS-CoV-2 Variants: Development of a Rapid Computational Method [0.03%]
评估赛诺菲sotrovimab抗体对SARS-CoV-2变异株中和活性的比较分析：开发快速计算方法
Dana Ashoor,Maryam Marzouq,M-Dahmani Fathallah
Dana Ashoor
Background: The rapid evolution of SARS-CoV-2 imposed a huge challenge on disease control. Immune evasion caused by genetic variations of the SARS-CoV-2 spike protein's immunogenic epitopes affects the efficiency of monoc...
Ethical Considerations in Human-Centered AI: Advancing Oncology Chatbots Through Large Language Models [0.03%]
以人为本的AI伦理考量：通过大型语言模型推进肿瘤学聊天机器人的发展
James C L Chow,Kay Li
James C L Chow
The integration of chatbots in oncology underscores the pressing need for human-centered artificial intelligence (AI) that addresses patient and family concerns with empathy and precision. Human-centered AI emphasizes ethical principles, em...
Correction: Mutations of SARS-CoV-2 Structural Proteins in the Alpha, Beta, Gamma, and Delta Variants: Bioinformatics Analysis [0.03%]
订正：SARS-CoV-2结构蛋白在Alpha、Beta、Gamma和Delta变异株中的突变：生物信息学分析
Saima Rehman Khetran,Roma Mustafa
Saima Rehman Khetran
[This corrects the article DOI: 10.2196/43906.]. ©Saima Rehman Khetran, Roma Mustafa. Originally published in JMIR Bioinformatics and Biotechnology (htt...
Published Erratum
JMIR bioinformatics and biotechnology. 2024 Aug 5:5:e64915. DOI:10.2196/64915 2024
Deep Learning-Based Identification of Tissue of Origin for Carcinomas of Unknown Primary Using MicroRNA Expression: Algorithm Development and Validation [0.03%]
基于深度学习的未知原发灶癌组织起源识别的微核糖核酸表达算法研发与验证
Ananya Raghu,Anisha Raghu,Jillian F Wise
Ananya Raghu
Background: Carcinoma of unknown primary (CUP) is a subset of metastatic cancers in which the primary tissue source of the cancer cells remains unidentified. CUP is the eighth most common malignancy worldwide, accounting ...
Molecular Docking Using Chimera and Autodock Vina Software for Nonbioinformaticians [0.03%]
面向生物信息学门外汉的分子对接（使用Chimera和Autodock Vina软件）
Sania Safdar Butt,Yasmin Badshah,Maria Shabbir et al.
Sania Safdar Butt et al.
In the field of drug discovery, many methods of molecular modeling have been employed to study complex biological and chemical systems. Experimental strategies are integrated with computational approaches for the identification, characteriz...
Nonfungible Tokens as a Blockchain Solution to Ethical Challenges for the Secondary Use of Biospecimens: Viewpoint [0.03%]
基于区块链的非同质化代币作为解决生物样本二次使用伦理挑战的观点方案
Marielle S Gross,Amelia J Hood,Robert C Miller Jr
Marielle S Gross
Henrietta Lacks' deidentified tissue became HeLa cells (the paradigmatic learning health platform). In this article, we discuss separating research on Ms Lacks' tissue from obligations to promote respect, beneficence, and justice for her as...
Novel Molecular Networks and Regulatory MicroRNAs in Type 2 Diabetes Mellitus: Multiomics Integration and Interactomics Study [0.03%]
2型糖尿病中的新型分子网络及其调控微小核糖核酸的组学研究
Manoj Khokhar,Dipayan Roy,Sojit Tomo et al.
Manoj Khokhar et al.
Background: Type 2 diabetes mellitus (T2DM) is a metabolic disorder with severe comorbidities. A multiomics approach can facilitate the identification of novel therapeutic targets and biomarkers with proper validation of ...
Decision of the Optimal Rank of a Nonnegative Matrix Factorization Model for Gene Expression Data Sets Utilizing the Unit Invariant Knee Method: Development and Evaluation of the Elbow Method for Rank Selection [0.03%]
基于肘部方法的秩选择的非负矩阵分解模型最优秩决策的制定与评估：用于基因表达数据集的单位不变膝部方法的发展和评估
Emine Guven
Emine Guven
Background: There is a great need to develop a computational approach to analyze and exploit the information contained in gene expression data. The recent utilization of nonnegative matrix factorization (NMF) in computati...
The Roles of NOTCH3 p.R544C and Thrombophilia Genes in Vietnamese Patients With Ischemic Stroke: Study Involving a Hierarchical Cluster Analysis [0.03%]
NOTCH3 p.R544C和血栓形成基因在越南缺血性卒中患者中的作用：一项分层聚类分析研究
Huong Thi Thu Bui,Quỳnh Nguyễn Thị Phương,Ho Cam Tu et al.
Huong Thi Thu Bui et al.
Background: The etiology of ischemic stroke is multifactorial. Several gene mutations have been identified as leading causes of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (C...