Daosong Wang,Jiayi Xie,Meng Zhao
Daosong Wang
Megakaryocytes (MKs) constitute a small portion of bone marrow cells and are primarily responsible for producing platelets, which are essential for hemostasis and wound healing. Recent studies have revealed that MKs and platelets perform di...
Hui Cheng
Hui Cheng
Jia Yu,Fang Wang
Jia Yu
Pre-transplantation levels of lysine (K)-specific methyltransferase 2A (KMT2A) partial tandem duplications can predict relapse of acute myeloid leukemia patients following haploidentical donor hematopoietic stem cell transplantation [0.03%]
移植前组蛋白甲基转移酶KMT2A偏位串联重复水平能够预测单倍型相合移植后急性髓系白血病患者复发风险
Dao-Xing Deng,Xiao-Hang Ma,Ze-Hua Wu et al.
Dao-Xing Deng et al.
We aimed to identify dynamic changes of lysine (K)-specific methyltransferase 2A partial tandem duplications (KMT2A-PTD) before and after haploidentical donor hematopoietic stem cell transplantation (HID HSCT) and explore the prognostic val...
Grzegorz K Przybylski,Julia Przybylska,Yangqiu Li
Grzegorz K Przybylski
The zinc finger transcription factor B-cell CLL/lymphoma 11B gene (BCL11B, CTIP2) plays a crucial role in T-cell development, but its role in T-cell malignancies has not yet been definitively clarified. In the literature, 2 contradictory hy...
Epigenetic modifications in hematopoietic ecosystem: a key tuner from homeostasis to acute myeloid leukemia [0.03%]
造血生态系统中的表观遗传学修饰：从稳态到急性髓系白血病的关键调节因素
Shuxin Yao,Rongxia Guo,Wen Tian et al.
Shuxin Yao et al.
Hematopoietic stem cells (HSCs) maintain homeostasis in the hematopoietic ecosystem, which is tightly regulated at multiple layers. Acute myeloid leukemia (AML) is a severe hematologic malignancy driven by genetic and epigenetic changes tha...
Ao Zhang,Wenbing Liu,Shaowei Qiu
Ao Zhang
Leukemias are a group of heterogeneous hematological malignancies driven by diverse genetic variations, and the advent of genomic sequencing technologies facilitates the investigation of genetic abnormalities in leukemia. However, these seq...
Zhidong Xie,Jing Liao,Jun Chen
Zhidong Xie
Adult megakaryopoiesis: when taking a short-cut results in a different final destination [0.03%]
成人巨核细胞生成：走捷径的结果不同终点
Wenxu Zhu,Gavin Tjin,Louise E Purton
Wenxu Zhu