Acupoint transplantation versus non-acupoint transplantation using autologous peripheral blood mononuclear cells in treating peripheral arterial disease [0.03%]
自体外周血单核细胞用于治疗周围动脉疾病的 acupuncture 移植与非 acupuncture 移植的比较研究
Wenjing Guo,Ling Pan,Ruiyu Yang et al.
Wenjing Guo et al.
Numerous studies have discussed the therapeutic outcomes of using cell therapy or acupuncture to treat peripheral artery disease (PAD). However, there are no long-term studies on the safety and efficacy of transplanting peripheral blood mon...
Immune checkpoint expression patterns on T cell subsets in light-chain amyloidosis: VISTA, PD-1, and TIGIT as potential therapeutic targets [0.03%]
轻链型淀粉样变性T细胞亚群中的免疫检查点表达模式:VISTA,PD-1和TIGIT作为潜在的治疗靶标
Jinghua Wang,Yujie Zhao,Pengjun Liao et al.
Jinghua Wang et al.
Amyloid light chain (AL) amyloidosis is a rare plasma cell dyscrasia with dismal prognosis. This study aims to investigate the T-cell immune checkpoint expression patterns in systemic AL amyloidosis and its relationship with clinicobiologic...
Efficacy and safety of letermovir prophylaxis for cytomegalovirus infection after hematopoietic stem cell transplantation [0.03%]
造血干细胞移植后预防性使用来特莫韦防治巨细胞病毒感染的有效性和安全性
Wen-Wen Li,Yong-Mei Zhang,Meng-Zhu Shen et al.
Wen-Wen Li et al.
Letermovir is a specific inhibitor of cytomegalovirus (CMV) terminase complex. Several studies have reported that letermovir can effectively prevent CMV activation after allogeneic hematopoietic stem cell transplantation (allo-HSCT). We aim...
Hematopoietic stem cell heterogeneity in non-human primates revealed by five-lineage output bias analysis [0.03%]
五系谱偏向分析揭示非人灵长类的造血干细胞异质性
Man Zhang,Di Liu,Yu Lan et al.
Man Zhang et al.
Understanding hematopoietic stem cell (HSC) heterogeneity is crucial for treating malignant blood disorders. Compared with mice, we have limited knowledge of the heterogeneity of human HSCs. Fortunately, non-human primates (NHPs) have becom...
The eighth International Forum on Stem Cells: virtual meeting, October 20-21, 2022 [0.03%]
第八届国际干细胞论坛:2022年10月20日至21日线上举行
Brian Eyden,Xiaochen Wang
Brian Eyden
Acute intestinal GVHD following donor-derived CD7-CAR-T-cell infusion in a child with Omicron COVID-19 [0.03%]
新冠奥密克戎株感染患儿输注CD7-CAR-T细胞后发生急性肠道移植物抗宿主病
Yu Lian,Zhilin Gao,Juanjuan Ti et al.
Yu Lian et al.
Targeting P21-activated kinase suppresses proliferation and enhances chemosensitivity in T-cell lymphoblastic lymphoma [0.03%]
靶向P21活化激酶可抑制T细胞淋巴母细胞瘤的增殖并增强其化疗敏感性
Ning Su,Yu Fang,Xu Chen et al.
Ning Su et al.
T-cell lymphoblastic lymphoma (T-LBL) is a highly aggressive non-Hodgkin lymphoma with a poor prognosis. P21-activated kinase (PAK) is a component of the gene expression-based classifier that can predict the prognosis of T-LBL. However, the...
Jia-Yi Wang,Liang Wang
Jia-Yi Wang
Chimeric antigen receptor (CAR)-T-cell therapies have exhibited remarkable efficacy in the treatment of hematologic malignancies, with 9 CAR-T-cell products currently available. Furthermore, CAR-T cells have shown promising potential for ex...