Pre-existing low-frequency resistance mutations increase the risk of antiretroviral treatment failure in HIV-1 naïve patients [0.03%]
人免疫缺陷病毒(HIV)初治患者中预先存在的低频抗药性突变增加抗逆转录病毒治疗失败风险
Yifan Su,Rentian Cai,Yinyin Zhu et al.
Yifan Su et al.
Efficacy and safety profiles of dolutegravir plus lamivudine vs . bictegravir/emtricitabine/tenofovir alafenamide in therapy-naïve adults with HIV-1 [0.03%]
多替拉韦联合拉米夫定与比克替拉韦/恩曲他滨/ tenofovir alafenamide治疗HIV-1初治成人患者的有效性和安全性：随机、双盲、III期临床试验四十八周结果分析
Yinghua Wei,Jin Li,Ruhong Xu et al.
Yinghua Wei et al.
Background: Dual regimen dolutegravir (DTG) plus lamivudine (3TC) has demonstrated non-inferior efficacy compared to DTG-based three-drug regimens (3DRs), yet directly comparative data regarding the efficacy and safety of...
Multicenter Study
Chinese medical journal. 2023 Nov 20;136(22):2677-2685. DOI:10.1097/CM9.0000000000002907 2023
Dietary vitamins modified the association of dietary iron with type 2 diabetes: the National Health and Nutrition Examination Survey, 2003-2014 [0.03%]
饮食维生素改变了饮食铁与2型糖尿病的关系：2003-2014年全国健康和营养检查调查数据的证据
Xiaoyan Wu,Jian Gao,Lin Zhu et al.
Xiaoyan Wu et al.
An atlas of immune cell transcriptomes in human immunodeficiency virus-infected immunological non-responders identified marker genes that control viral replication [0.03%]
人免疫缺陷病毒(HIV)感染免疫无应答者中免疫细胞转录组的图谱鉴定出控制病毒复制的标记基因
Yahong Chen,Xin Li,Shuran Liu et al.
Yahong Chen et al.
Background: Previous studies have examined the bulk transcriptome of peripheral blood immune cells in acquired immunodeficiency syndrome patients experiencing immunological non-responsiveness. This study aimed to investig...
Hu Wang,Siqi Xu,Shuang Li et al.
Hu Wang et al.
Over the past few years, the human virome and its complex interactions with microbial communities and the immune system have gained recognition as a crucial factor in human health. Individuals with compromised immune function encounter dist...
Zhicheng Hu,Ligang Ding,Yan Yao
Zhicheng Hu
Atrial fibrillation (AF), the most common sustained arrhythmia, is associated with a range of symptoms, including palpitations, cognitive impairment, systemic embolism, and increased mortality. It places a significant burden on healthcare s...
Consistent efficacy of B/F/TAF in treatment-naïve HIV patients across different baseline HIV-1 RNA levels at week 48 [0.03%]
B/F/TAF治疗初治HIV患者时，在不同基线HIV-1 RNA水平受试者中的疗效一致：第48周结果
Kun He,Yihong Zhou,Honghong Yang et al.
Kun He et al.
Li Ye,Chuan Tian,Ye Li et al.
Li Ye et al.
Aging is accompanied by significant inhibition of hematopoietic and immune system function and disruption of bone marrow structure. Aging-related alterations in the inflammatory response, immunity, and stem cell niches are at the root of he...
Associations between parental adherence to healthy lifestyles and cognitive performance in offspring: A prospective cohort study in China [0.03%]
中国父母的健康生活方式与后代认知表现之间的关联：一项前瞻性队列研究
Rongxia Lv,Yuhui Huang,Siyi Huang et al.
Rongxia Lv et al.
Background: Previous studies have reported associations of specific maternal and paternal lifestyle factors with offspring's cognitive development during early childhood. This study aimed to investigate the prospective as...
Safety and efficacy of PD-1 inhibitors in HIV-infected patients with severe comorbidities: a prospective observational cohort study [0.03%]
HIV合并严重并发症患者中PD-1抑制剂的安全性及疗效：前瞻性观察队列研究
Xueling Zhu,Xiang Liu,Zhikai Wan et al.
Xueling Zhu et al.
Observational Study
Chinese medical journal. 2023 Nov 20;136(22):2750-2752. DOI:10.1097/CM9.0000000000002883 2023