Dietary tryptophan supplementation prevents sepsis by enhancing macrophage bacterial defense through GPR37 activation [0.03%]
色氨酸通过活化GPR37增强巨噬细胞细菌防御功能从而预防脓毒症
Shihao Xie,Fengyuan Lyu,Kai Gao et al.
Shihao Xie et al.
Background: Sepsis, a critical and life-threatening condition, is one of the most common causes of death among inpatients. Emerging evidence suggests that active metabolites derived from gut microbe-associated metabolism ...
Conversion surgery after immunotherapy and chemotherapy for gastric cancer with peritoneal metastasis or positive peritoneal cytology: A retrospective cohort study [0.03%]
胃癌腹膜转移或腹腔细胞学阳性的患者接受免疫及化疗后转手术治疗的回顾性队列研究
Huayuan Liang,Hailun Huang,Qing Xie et al.
Huayuan Liang et al.
Background: The efficacy of conversion therapy for gastric cancer with peritoneal metastasis (P1) and/or positive peritoneal lavage cytology (CY1) treated with immunotherapy remains unclear. This study aimed to clarify cl...
National and regional lifetime risks of developing and dying from digestive system cancers in China: Findings of the Global Burden of Disease Study 2023 [0.03%]
中国消化系统癌症终身发病和死亡风险:全球疾病负担研究(2023)结果
Qian Mao,Zhenping Zhao,Jiangmei Liu et al.
Qian Mao et al.
Background: Digestive system cancers are a leading cause of death in China, with a growing projected burden. Yet, data on the lifetime risk (LTR) of these cancers remain limited. We aimed to estimate the LTR of digestive ...
Association of long-term exposure to lower low-density lipoprotein cholesterol with neuroimaging metrics: A population-based cohort study [0.03%]
长期暴露于较低低密度脂蛋白胆固醇与神经影像学指标的关系:一项基于人群的队列研究
Jing Sun,Ying Hui,Jing Li et al.
Jing Sun et al.
Background: Limited evidence exists regarding the relationship between long-term exposure to low concentrations of low-density lipoprotein cholesterol (LDL-C) and brain structural integrity. This study aimed to examine th...
Guideline for the diagnosis and treatment of arthropathic psoriasis (psoriatic arthritis) (2026 edition) [0.03%]
银屑病关节炎(附有关节型银屑病)诊断与治疗指南(2026版)
Yuling Shi,Shengming Dai,Zhuoli Zhang et al.
Yuling Shi et al.
Tiantian Wang,Zhen Hong
Tiantian Wang
Sarcopenia, characterized by the age-related decline in skeletal muscle mass, strength, and function, is associated with high healthcare costs and significant health risks, including falls, fractures, functional decline, and mortality. Desp...
Synopsis of the 2025 guideline for the diagnosis and management of adult primary immune thrombocytopenia [0.03%]
2025年成人原发免疫性血小板减少症诊疗指南概要
Xinguang Liu,Yu Hu,Ming Hou
Xinguang Liu
Life's Essential 8 and the incidence and progression trajectory of chronic lung diseases: A multistate analysis of a prospective cohort study [0.03%]
生命八大基本要素与慢性肺疾病的发病及进展轨迹:前瞻性队列研究的多状态分析
Yanqiu Zou,Li Zhang,Yanjun Li et al.
Yanqiu Zou et al.
Background: The association of Life's Essential 8 (LE8) with the development of first chronic lung disease (FCLD), progression to chronic lung multimorbidity (CLM), and subsequent mortality remains inconclusive. In additi...
XBP1-mediated mitochondrial damage activates the mtDNA/STING/NLRP3 pathway to delay diabetic wound healing [0.03%]
XBP1介导的线粒体损伤通过mtDNA/STING/NLRP3通路延迟糖尿病创面修复
Min Yi,Wei Yan,Liying Tu et al.
Min Yi et al.
Background: Diabetic wounds (DBW) are characterized by high levels of reactive oxygen species (ROS) and pro-inflammatory factors; reducing inflammation is therefore a key strategy in the treatment of chronic diabetic woun...
Effect of cytoreductive chemotherapy on the incidence of differentiation syndrome in patients with newly diagnosed acute promyelocytic leukemia [0.03%]
根除性化疗对新诊断的急性早幼粒细胞白血病患者分化综合征发病率的影响
Huijuan Lou,Hailang Xu,Huanxin Zhang et al.
Huijuan Lou et al.