Xiaojie Wang,Yujia Li,Qingqing Chu et al.
Xiaojie Wang et al.
Cellular senescence, stable cell cycle arrest that can be triggered in normal cells in response to various intrinsic and extrinsic stressors, has been highlighted as one of the most important mechanisms involved in kidney diseases. It not o...
Transposable elements in health and disease: Molecular basis and clinical implications [0.03%]
可移动元件与健康和疾病:分子基础及临床意义
Yaqiang Hong,Nian Liu
Yaqiang Hong
Transposable elements (TEs), once considered genomic "junk", are now recognized as critical regulators of genome function and human disease. These mobile genetic elements-including retrotransposons (long interspersed nuclear elements [LINE-...
Sa Guo,Jiangling Luo,Cen Wu et al.
Sa Guo et al.
Advances in understanding the etiology and pathogenesis of chronic pancreatitis [0.03%]
慢性胰腺炎发病机制与病因研究进展
Siying Liu,Yongjun Wang,Wei Jiang
Siying Liu
Global, regional, and national burdens of shoulder dislocation in adolescents and young adults, 1990-2021: A population-based study [0.03%]
1990年至2021年青少年和年轻人肩关节脱位的全球、区域和国家负担:基于人群的研究
Hongfu Jin,Guoxu Zhang,Sijie Chen et al.
Hongfu Jin et al.
CRISPR/Cas9-engineered universal CD123/B7-H3 tandem CAR-T cell for the treatment of acute myeloid leukemia [0.03%]
基于CRISPR/Cas9编辑的通用型CD123/B7-H3双靶点CAR-T细胞治疗急性髓系白血病
Hexian Li,Qizhong Lu,Zhengyu Yu et al.
Hexian Li et al.
Background: Autologous chimeric antigen receptor T (CAR-T) cell therapy has demonstrated efficacy in the treatment of acute myeloid leukemia (AML). Nevertheless, the intrinsic characteristics of autologous therapy, such a...
Vitamin E supplementation and increased risk of gestational hypertension and preeclampsia in women undergoing assisted reproductive technologies [0.03%]
维生素E补充与辅助生殖技术妊娠期高血压和子痫前期风险增加的关系
Xiaolin Yang,Yuanyan Dou,Lingmin Hu et al.
Xiaolin Yang et al.
Background: Existing literature regarding the influence of vitamin E (VE) supplementation on the risk of gestational hypertension (GH) and preeclampsia (PE) remains controversial. Our study aimed to assess the association...
Off-the-shelf human umbilical cord mesenchymal stromal cell product in acute-on-chronic liver failure: A multicenter phase I/II clinical trial [0.03%]
胎盘脐带间充质干细胞治疗急性-on-慢性肝衰竭的临床研究:I/II期多中心临床试验
Lina Cui,Huaibin Zou,Shaoli You et al.
Lina Cui et al.
SMUG1 promotes the progression of pancreatic cancer via AKT signaling pathway through binding with FOXQ1 [0.03%]
SMUG1通过与FOXQ1结合促进胰腺癌的进展的AKT信号通路中发挥作用
Zijian Wu,Wei Wang,Jie Hua et al.
Zijian Wu et al.
Background: Pancreatic cancer is a lethal malignancy prone to gemcitabine resistance. The single-strand selective monofunctional uracil DNA glycosylase (SMUG1), which is responsible for initiating base excision repair, ha...
Aging and perioperative brain health: Mechanisms, management, and future [0.03%]
围手术期老年人脑健康:机制、管理与未来展望
Peilin Cong,Qian Chen,Qianqian Wu et al.
Peilin Cong et al.
Globally, over 300 million surgeries are performed each year, and more than 50% of surgeries involve patients aged 65 and older. Aging poses significant challenges to perioperative brain health, as the deterioration of brain structure and f...