Therapeutic role of miR-26a on cardiaorenal injury in mice model of angiotensin-II induced chronic kidney disease through inhibition of LIMS1/ILK pathway [0.03%]
miR-26a通过抑制LIMS1/ILK通路对ANG II诱导的慢性肾病小鼠模型的心肾损伤的治疗作用
Weijie Ni,Yajie Zhao,Jinxin Shen et al.
Weijie Ni et al.
Background: Chronic kidney disease (CKD) is associated with common pathophysiological processes, such as inflammation and fibrosis, in both the heart and the kidney. However, the underlying molecular mechanisms that drive...
Development of a droplet digital polymerase chain reaction assay for the sensitive detection of total and integrated HIV-1 DNA [0.03%]
用于敏感检测总HIV-1和整合型HIV-1 DNA的数字PCR检测方法的建立
Lin Yuan,Zhiying Liu,Xin Zhang et al.
Lin Yuan et al.
Background: Total human immunodeficiency virus (HIV) DNA and integrated HIV DNA are widely used markers of HIV persistence. Droplet digital polymerase chain reaction (ddPCR) can be used for absolute quantification without...
Clinical treatment procedure and experience of six gene-edited pig-rhesus monkey heterotopic heart xenotransplantation [0.03%]
六例基因编辑猪心异种移植于恒河猴的临床治疗流程和经验分享
Bing Zhang,Pengfei Ji,Langang Peng et al.
Bing Zhang et al.
Granulomatosis with polyangiitis presented as multiple cutaneous abscesses after hysterectomy [0.03%]
子宫切除术后出现的多发性皮肤脓肿的肉芽肿性多血管炎
Xiaoting Song,Mengrui Li,Yinggai Song et al.
Xiaoting Song et al.
Incidence, prevalence, and causes of spinal injuries in China, 1990-2019: Findings from the Global Burden of Disease Study 2019 [0.03%]
中国1990年至2019年脊柱损伤的发生率、流行率和原因：来自全球疾病负担研究2019年的发现
Chenjun Liu,Tingling Xu,Weiwei Xia et al.
Chenjun Liu et al.
Background: Spinal injuries are an urgent public health priority; nevertheless, no China-wide studies of these injuries exist. This study measured the incidence, prevalence, causes, regional distribution, and annual trend...
Associations of demographics, aggravating factors, comorbidities, and treatments with atopic dermatitis severity in China: A national cross-sectional study [0.03%]
中国中人口统计学特征、诱发因素、合并症和治疗与特应性皮炎严重程度的关联性研究：一次全国横断面调查研究
Jiahui Zhao,Zhixin Zhang,Hongguang Chen et al.
Jiahui Zhao et al.
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disorder impacting populations worldwide, although its clinical characteristics and patient demographics remain uncharacterized in China. The aim of this s...
Neoadjuvant therapy with immune checkpoint inhibitors in combination with chemotherapy vs . chemotherapy alone in HER2(-) locally advanced gastric cancer: A propensity score-matched cohort study [0.03%]
免疫检查点抑制剂联合化疗对比单用化疗新辅助治疗HER2（-）局部晚期胃癌：一项倾向评分匹配队列研究
Gehan Xu,Tianjiao Liu,Jingyi Shen et al.
Gehan Xu et al.
Background: This study aims to compare the efficacy between neoadjuvant immune checkpoint inhibitors (ICIs) plus chemotherapy vs . chemotherapy, and neoadjuvant triplet vs . doublet chemotherapeutic regimens in locally ad...
Effect of long-acting polyethylene glycol recombinant human growth hormone dosages in pediatric practice: A pooled analysis of two phase IV randomized controlled trials [0.03%]
长链聚乙二醇重组人生长激素在儿科实践中的剂量效果：两项四期随机对照试验的综合分析
Ling Hou,Xuefeng Chen,Hongwei Du et al.
Ling Hou et al.
Diagnosis and treatment of gallbladder polypoid lesions: Current practices and future prospects [0.03%]
胆囊息肉样病变的诊断和治疗：现状与前景
Kun Wang,Qingpeng Xu,Lu Xia et al.
Kun Wang et al.
Gallbladder polypoid lesions (GPLs) refer to any elevated lesion of the mucosal surface of the gallbladder wall, and the prevalence is estimated to be between 0.9% and 12.1%. GPLs include benign polyps and malignant polyps. Benign polyps ar...
Driving effect of P16 methylation on telomerase reverse transcriptase-mediated immortalization and transformation of normal human fibroblasts [0.03%]
P16甲基化对正常人成纤维细胞衰老逆转及转化的驱动作用机制研究
Xuehong Zhang,Paiyun Li,Ying Gan et al.
Xuehong Zhang et al.
Background: P16 inactivation is frequently accompanied by telomerase reverse transcriptase (TERT) amplification in human cancer genomes. P16 inactivation by DNA methylation often occurs automatically during immortalizatio...