Disease burden and economic impact of osteoarthritis in working-age individuals (aged 30-64 years): Insights from the Global Burden of Disease Study 2021 [0.03%]
全球疾病负担研究(2021)中的骨关节炎发病与经济负担:30至64岁劳动年龄人口的患病情况及经济影响
Zhongyu Luo,Xiaoying Zhong,Zhou Zhu et al.
Zhongyu Luo et al.
Background: Osteoarthritis (OA) in working-age individuals (aged 30-64 years) adversely affects health and reduces productivity. In this study, the disease burden and economic impact of OA on this demographic are examined...
Artificial intelligence in inflammatory bowel disease: From current evidence, clinical translation, and the road to precision medicine [0.03%]
人工智能在炎症性肠病中的应用:现状、临床转化和精准医学之路
Robert Hughes,Antonio Lo Bello,Raymond Fueng-Hin Liang et al.
Robert Hughes et al.
Artificial intelligence (AI) is rapidly transforming healthcare, supporting disease management and enabling outcome prediction across multiple clinical settings. Inflammatory bowel diseases (IBD) are complex, heterogeneous conditions whose ...
Tisotumab vedotin versus chemotherapy in Chinese patients with recurrent or metastatic cervical cancer with disease progression on or after systemic therapy [0.03%]
蒂索尼姆单抗 vedotin 治疗系统治疗后复发或转移性宫颈癌中国患者的疗效:随机、活性对照的 3 期临床试验
Lingying Wu,Lihong Chen,Dapeng Li et al.
Lingying Wu et al.
Anti-PD-1 monoclonal antibody suppresses hepatitis B virus in patients with hepatocellular carcinoma [0.03%]
抗PD-1单克隆抗体可抑制肝癌患者的乙肝病毒感染
Chuanhua Zhao,Yanqiao Zhang,Gang Wang et al.
Chuanhua Zhao et al.
Wenhui Liu,Baiyuan Fan,Yu Qian et al.
Wenhui Liu et al.
Nanoparticles derived from various sources have been widely investigated as biological therapeutic agents and drug carriers for cancer treatment. Among them, plant-derived vesicle-like nanoparticles (PDVLNs) have attracted considerable inte...
PI3K-Akt signaling network crosstalk in cerebral ischemia/reperfusion injury: Mechanisms and therapeutic implications [0.03%]
缺血/再灌注损伤中PI3K-Akt信号网络的互作机制及治疗意义研究进展
Wenzhe Yang,Qian Yang,Zhihui Wang et al.
Wenzhe Yang et al.
Cerebral ischemia (CI) is an acute central nervous system disorder resulting from the abrupt interruption of blood flow to brain tissue. The restoration of blood flow during treatment is frequently accompanied by cerebral ischemia/reperfusi...
Target trial emulation: A practical framework for credible real-world evidence of healthcare interventions [0.03%]
目标试验模拟:生成可靠的现实世界证据以评估医疗保健干预措施的实际框架
Yan Ren,Yulong Jia,Lingyan Liu et al.
Yan Ren et al.
Clinical study of pronase for improving visibility and safety in colonoscopy [0.03%]
关于派普酶提高结肠镜诊疗安全性和可靠性的临床研究
Bo Zhang,Tanzhou Chen,Yu Chen et al.
Bo Zhang et al.
Background: This is a multicenter, randomized, double-blind, placebo-controlled interventional clinical study to evaluate the efficacy and safety of pronase in improving visibility in colonoscopy and to evaluate whether p...
Insulin-like growth factor binding protein 4 (IGFBP4)high fibroblasts contribute to extracellular matrix degradation in rheumatoid arthritis [0.03%]
高胰岛素样生长因子结合蛋白4(IGFBP4)成纤维细胞在类风湿关节炎中促进基质金属蛋白酶的表达和细胞外基质降解
Yangyang Liang,Jing Xue,Zeqin Zhu et al.
Yangyang Liang et al.
Glucocorticoid steroids in outpatients with moderate COVID-19 and radiological signs of pneumonia: A cohort study [0.03%]
糖皮质激素治疗伴有影像学表现的普通门诊患者新冠肺炎中度病例:队列研究
Jiuyang Xu,Rongrong Song,Yeming Wang et al.
Jiuyang Xu et al.