Caffeic acid tablets plus high-dose dexamethasone versus placebo plus high-dose dexamethasone in patients with newly diagnosed immune thrombocytopenia: A multicenter, double-blind, randomized, controlled, phase 2 trial [0.03%]
Newly诊断免疫性血小板减少症患者使用咖啡酸片联合大剂量地塞米松与安慰剂联合大剂量地塞米松的比较:一项多中心、双盲、随机对照II期临床试验
Ruting Wang,Yang Liu,Ruixue Wang et al.
Ruting Wang et al.
Background: Standard initial therapy with intensive glucocorticoids requires further optimization due to high relapse rates and unsatisfying long-term outcomes in patients with primary immune thrombocytopenia (ITP). Caffe...
Optimization of biosafety laboratory management via an AI-driven intelligent system [0.03%]
基于人工智能的生物安全实验室智能化管理系统优化研究
Chang Qi,Anqi Lin,Anghua Li et al.
Chang Qi et al.
Erianin induces GSDMD-dependent pyroptosis and synergistically enhances doxorubicin efficacy via the PI3K/AKT signaling pathway in diffuse large B-cell lymphoma [0.03%]
依里那宁通过PI3K / AKT信号通路诱导GSDMD依赖性细胞焦亡并协同增强弥漫性大B细胞淋巴瘤的阿霉素疗效
Hanwei Mei,Minghan Qiu,Ruxue Liu et al.
Hanwei Mei et al.
Background: Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma and is characterized by high aggressiveness and rapid growth. Erianin, a natural compound derived from the Chinese herb Den...
Ling Zhou,Meng Peng,Yuming Chen et al.
Ling Zhou et al.
Xuefeng Luo,Guangchuan Wang,Li Yang et al.
Xuefeng Luo et al.
The Baveno Cooperation is a consortium of internationally renowned experts committed to setting standards for the clinical management of patients with advanced chronic liver disease, with a particular emphasis on complications related to po...
Novel paradigms in KRAS targeting: Unveiling strategies to combat drug resistance [0.03%]
KRAS靶向的新范式:揭示克服药物抵抗的策略
Xiyuan Luo,Feihan Zhou,Yuemeng Tang et al.
Xiyuan Luo et al.
The Kirsten rat sarcoma viral oncogene homolog (KRAS) mutation is one of the most prevalent activating alterations in cancer. It indicates a poor overall prognosis due to its highly invasive nature. Although several KRAS inhibitors have bee...
Causal relationship between gastroesophageal reflux disease and pneumoconiosis: Evidence from a clinical retrospective study and two-sample Mendelian randomization [0.03%]
基于临床回顾性研究和两样本孟德尔随机化的胃食管反流病与尘肺病因果关系证据分析
Fengyuan Yu,Qianqian Xu,Jin He et al.
Fengyuan Yu et al.
GSTP1-mediated inhibition of ACSL4-dependent ferroptosis via JNK pathway in DOX-induced cardiomyopathy [0.03%]
GSTP1通过JNK途径介导抑制ACSL4依赖性铁死亡在多柔比星诱导的心肌病中的作用
Mingbo Wu,Ye Zhao,Dong Li et al.
Mingbo Wu et al.
Background: Doxorubicin hydrochloride (DOX) is extensively used in the treatment of various tumors. However, its clinical application is limited due to dose-dependent cardiotoxicity. Currently, few effective strategies ex...
Histopathological images-based deep-learning for risk stratification of uveal melanoma [0.03%]
基于深度学习的脉络膜黑色素瘤风险分层(英语)
Qi Wan,Chen Hou,Ran Wei et al.
Qi Wan et al.