The switch triggering the invasion process: Lipid metabolism in the metastasis of hepatocellular carcinoma [0.03%]
肝细胞癌转移中触发侵袭过程的开关：脂质代谢
Jiaqian Zhang,Zhicheng Zhang,Zhangfan Wu et al.
Jiaqian Zhang et al.
In humans, the liver is a central metabolic organ with a complex and unique histological microenvironment. Hepatocellular carcinoma (HCC), which is a highly aggressive disease with a poor prognosis, accounts for most cases of primary liver ...
Secular trend and projection of overweight and obesity among Chinese children and adolescents aged 7-18 years from 1985 to 2019: Rural areas are becoming the focus of investment [0.03%]
中国农村地区7至18岁儿童青少年超重肥胖流行趋势及2019年估计预测分析：农村成为防控重点区域
Jiajia Dang,Yunfei Liu,Shan Cai et al.
Jiajia Dang et al.
Background: The urban-rural disparities in overweight and obesity among children and adolescents are narrowing, and there is a need for long-term and updated data to explain this inequality, understand the underlying mech...
Hearing loss prevalence and burden of disease in China: Findings from provincial-level analysis [0.03%]
中国听力损失流行率和疾病负担的省份层面分析结果
Yu Wang,Yang Xie,Minghao Wang et al.
Yu Wang et al.
Background: Without timely and effective rehabilitation, hearing loss may profoundly affect human life quality. China has a large population of hearing-impaired individuals, which imposes a heavy health burden on society....
Radiotherapy enhances efficacy of PD-1 inhibitors in advanced hepatocellular carcinoma: A propensity-matched real-world study [0.03%]
一项倾向匹配的现实世界研究：放射治疗可增强PD-1抑制剂在晚期肝细胞癌中的疗效
Shujung Hsu,Yencheng Chao,Yong Hu et al.
Shujung Hsu et al.
Background: To address the need for immunotherapy in patients with advanced primary hepatocellular carcinoma (HCC), combination with radiotherapy (RT) has emerged as a promising strategy. In preclinical studies, irradiate...
Role of maternal-fetal immune tolerance in the establishment and maintenance of pregnancy [0.03%]
母胎免疫耐受在妊娠建立和维持中的作用
Jingjing Wang,Tao Han,Xiaoming Zhu
Jingjing Wang
Normal pregnancy is a contradictory and complicated physiological process. Although the fetus carries the human leukocyte antigen (HLA) inherited from the paternal line, it does not cause maternal immune rejection. As the only exception to ...
SIRT3 protects endometrial receptivity in patients with polycystic ovary syndrome [0.03%]
SIRT3保护多囊卵巢综合征患者的子宫内膜容受性
Zhonghong Zeng,Hongying Shan,Mingmei Lin et al.
Zhonghong Zeng et al.
Background: The sirtuin family is well recognized for its crucial involvement in various cellular processes. Nevertheless, studies on its role in the human endometrium are limited. This study aimed to explore the expressi...
Direct reprogramming of fibroblasts into functional hepatocytes via CRISPRa activation of endogenous Gata4 and Foxa3 [0.03%]
利用CRISPRa激活Gata4和Foxa3内源基因直接将成纤维细胞重编程为具有功能的肝细胞
Jiacheng Li,Ruopu Li,Xue Bai et al.
Jiacheng Li et al.
Background: The ability to generate functional hepatocytes without relying on donor liver organs holds significant therapeutic promise in the fields of regenerative medicine and potential liver disease treatments. Cluster...
Comparing the effects of dual-task training and single-task training on walking, balance and cognitive functions in individuals with Parkinson's disease: A systematic review [0.03%]
对比任务训练和单一任务训练对帕金森病患者步行、平衡和认知功能影响的系统评价
Xiaoying Lin,Yanming Zhang,Xiaowei Zhang et al.
Xiaoying Lin et al.
Background: This systematic review aimed to examine whether dual-task (DT) training was superior to single-task (ST) training in improving DT walking, balance and cognitive functions for individuals with Parkinson's disea...
Consensus of Chinese experts on glioma multidisciplinary team management (2nd edition) [0.03%]
中国胶质瘤多学科诊治专家共识(2021年版)
Jinsong Wu,Zhirui Zhou,Zanyi Wu et al.
Jinsong Wu et al.
Circulating tumor DNA- and cancer tissue-based next-generation sequencing reveals comparable consistency in targeted gene mutations for advanced or metastatic non-small cell lung cancer [0.03%]
基于循环肿瘤DNA和癌症组织的下一代测序发现晚期或转移性非小细胞肺癌中靶向基因突变的一致性相当
Weijia Huang,Kai Xu,Zhenkun Liu et al.
Weijia Huang et al.
Background: Molecular subtyping is an essential complementarity after pathological analyses for targeted therapy. This study aimed to investigate the consistency of next-generation sequencing (NGS) results between circula...