Impact of joint effect of parental anthropometrics on fetal growth trajectories: A national multicenter cohort study [0.03%]
父母体格指标联合作用对胎儿生长轨迹的影响——一项全国多中心队列研究
Yu Liu,Jun Ma,Jinmin Wang et al.
Yu Liu et al.
Yixuan Yin,Jianing Gao,Kezhong Zhang et al.
Yixuan Yin et al.
Parkinson's disease (PD) is a progressive neurodegenerative disorder associated with a rapidly rising global disease burden and a substantial decline in patients' quality of life. Although currently approved therapies offer symptomatic reli...
Incidence, DALYs, and death rates of chronic kidney disease in China, 1990-2023: Results from the Global Burden of Disease Study 2023 [0.03%]
中国慢性肾脏疾病发病、伤残调整寿命年和死亡率的变化（1990年至2023年）：全球疾病负担研究（2023年）结果
Jinwei Wang,Minghui Zhao,Luxia Zhang
Jinwei Wang
Background: Chronic kidney disease (CKD) is a global public health concern that causes a remarkable disease burden. Although the prevalence of CKD in China has been investigated by previous national surveys, the incidence...
Reclassifying renal cell carcinoma with pathologic lymph node metastasis: An approach to refining prognostic stratification in patients with AJCC III and IV stages [0.03%]
病理上有淋巴结转移的肾细胞癌的再分类：一种改善AJCC III和IV期患者预后分层的方法
Xu Bai,Tongyu Jia,Houming Zhao et al.
Xu Bai et al.
Background: Lymph node metastasis is a well-established prognostic factor in renal cell carcinoma (RCC); however, the prognosis varies among patients with nodal metastases. Subclassification by T category may improve the ...
Prevalence, trends, and maternal-fetal outcomes in pregnant women with polycystic ovary syndrome in Chinese mainland [0.03%]
中国大陆多囊卵巢综合征孕妇的患病率、趋势及母儿结局研究
Yanping Zhang,Yanxia Xie,Yi Mu et al.
Yanping Zhang et al.
Background: Epidemiological data and the impact of China's fertility policies on pregnant women with polycystic ovary syndrome (PCOS) are limited. This study aims to investigate the prevalence, trends, and maternal-fetal ...
Niraparib treatment patterns and outcomes in first-line maintenance therapy for ovarian cancer: The RENI-1 study [0.03%]
尼拉帕利一线维持治疗卵巢癌的用药模式和疗效：雷妮一研究
Jing Zuo,Ke Wang,Zhumei Cui et al.
Jing Zuo et al.
Background: Prospective real-world data on poly(adenosine diphosphate-ribose [ADP]-ribose) polymerase inhibitors (PARPi) as first-line maintenance therapy (1LMT) for ovarian cancer are limited. This study was conducted to...
Zhengzhao Liu,Wenbao Hu,Lin Sun et al.
Zhengzhao Liu et al.
Mitochondria are central to cellular energy metabolism, and their functional integrity is essential for maintaining cellular homeostasis and life processes. Mitochondrial quality control (MQC) encompasses a complex network of mechanisms-inc...
Circulating circRNAs at the frontier of cancer detection, prognosis, and therapy [0.03%]
循环circRNA在癌症检测、预后和治疗方面的前沿研究
Yue Zhang,Guanxuan Chen,Zhaoyun Liu et al.
Yue Zhang et al.
Circular RNAs (circRNAs) are distinguished from other noncoding RNAs by their unique loop structure, without 5' polar ends and 3' polyadenylated tails. They are stable and abundant in a wide range of eukaryotic taxa and exert functions via ...
Feng Guo,Yi Song,Guijun Qin
Feng Guo
The increasing global prevalence of diabetes mellitus (DM) necessitates the development of innovative therapeutic strategies that effectively address its symptoms and alleviate its enduring pathological consequences. Stem cells (SCs), which...
A selective BRG1 inhibitor targeting bromodomain sensitizes hepatocellular carcinoma to chemoradiotherapy by disrupting the DNA damage response [0.03%]
选择性BRG1溴结构域抑制剂通过破坏DNA损伤反应增强肝细胞癌化放疗敏感性
Qing Tao,Ziqi Zhu,Yuwei Chen et al.
Qing Tao et al.
Background: The poor response to ionizing radiation and chemotherapies remains a significant clinical challenge for unresectable hepatocellular carcinoma (HCC). BRG1, the core ATPase subunit of switch/sucrose non-fermenta...