Jiannan Wang,Lijun Dai,Zhentao Zhang
Jiannan Wang
Neurodegenerative diseases constitute a group of chronic disorders characterized by the progressive loss of neurons. Major neurodegenerative conditions include Alzheimer's disease, Parkinson's disease, Huntington's disease, frontotemporal l...
Efficacy and safety of the triple combination cream in Chinese patients with moderate to severe melasma: A multi-center, randomized, double-blind, three-arm, parallel-group, placebo-controlled clinical trial [0.03%]
中国中重度黄褐斑患者三联复方霜剂疗效及安全性研究：一项多中心随机双盲平行对照安慰剂临床试验
Li Zhang,Geyao Xu,Quanzhong Liu et al.
Li Zhang et al.
Efficacy and safety of benvitimod 1% cream for atopic dermatitis in patients aged 2 years and older: A phase III randomized clinical trial [0.03%]
贝他司汀软膏治疗2岁（含）以上 atopice患者：III期随机临床试验
Yan Zhao,Zhu Wei,Yanyan Feng et al.
Yan Zhao et al.
Background: Benvitimod (tapinarof), an aryl hydrocarbon receptor (AhR) agonist approved for treating plaque psoriasis, is being investigated as a potential treatment for atopic dermatitis (AD). The aim of this study was t...
Li Zhang,Qingchun Diao,Xia Dou et al.
Li Zhang et al.
Single-cell analysis identifies PI3+S100A7+ keratinocytes in early cervical squamous cell carcinoma with HPV infection [0.03%]
单细胞分析鉴定出HPV感染早期宫颈鳞癌中的PI3+S100A7+角质形成细胞
Peiwen Fan,Danning Dong,Yaning Feng et al.
Peiwen Fan et al.
Background: Cervical squamous cell carcinoma (CESC), the most common subtype of cervical cancer, is primarily caused by the high-risk human papillomavirus (HPV) infection and genetic susceptibility. Single-cell RNA sequen...
H3K9 acetylation-dependent CHAC1 transcription in dihydroartemisinin-induced hepatic stellate cell ferroptosis [0.03%]
二氢青蒿素诱导的肝星状细胞铁死亡过程中组蛋白H3K9乙酰化依赖性的CHAC1转录激活作用
Min Shen,Wenshu Han,Liangliang Cai et al.
Min Shen et al.
Background: The activation of hepatic stellate cells (HSCs) plays a crucial role in the progression of liver fibrosis, and eliminating activated HSCs is regarded as an effective strategy for combating fibrosis. Ferroptosi...
Development and validation of a prediction score for subtype diagnosis of primary aldosteronism [0.03%]
原发性醛固酮增多症亚型诊断预测评分的建立和验证
Ping Liu,Wei Zhang,Jiao Wang et al.
Ping Liu et al.
Diabetic vascular calcification inhibited by soluble epoxide hydrolase gene deletion via regressing NID2-mediated IGF2-ERK1/2 signaling pathway [0.03%]
通过回归IGF2-ERK1 / 2信号通路介导的NID2抑制可溶性环氧化物水解酶基因删除的糖尿病血管钙化
Yueting Cai,Shuiqing Hu,Jingrui Liu et al.
Yueting Cai et al.
Background: Epoxyeicosatrienoic acids (EETs), which are metabolites of arachidonic acid catalyzed by cytochrome P450 epoxygenase, are degraded into inactive dihydroxyeicosatrienoic acids by soluble epoxide hydrolase (sEH)...
Association between gut microbiota and lymphomas: A bidirectional multivariable Mendelian randomization study [0.03%]
肠道微生物群与淋巴瘤的关联：一项双向多变量孟德尔随机化研究
Dahua Lan,Jingkang Xiong,Chaokun Hong et al.
Dahua Lan et al.
Isoxanthohumol inhibits MRGPRX2-mediated mast cell activation reducing inflammation in rosacea [0.03%]
异黄酮抑制MRGPRX2介导的肥大细胞活化从而减少玫瑰痤疮炎症
Kathy Z Wang,Tao Jia,Ruiqi Li et al.
Kathy Z Wang et al.